Search Results - "Winston, J. H"

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    Neurological and cellular regulation of visceral hypersensitivity induced by chronic stress and colonic inflammation in rats by Chen, J, Winston, J.H, Sarna, S.K

    Published in Neuroscience (17-09-2013)
    “…Highlights • Novel findings on visceral hypersensitivity, inflammation and stress. • Chronic stress exacerbates hypersensitivity in the presence of…”
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    Journal Article
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    Role of brain‐derived neurotrophic factor in the pathogenesis of distention‐associated abdominal pain in bowel obstruction by Fu, Y., Lin, Y. M., Winston, J. H., Radhakrishnan, R., Huang, L.‐Y. M., Shi, X. Z.

    Published in Neurogastroenterology and motility (01-10-2018)
    “…Background Previous studies found that visceral sensitivity is increased in bowel obstruction (BO). We hypothesized that mechanical stress‐induced expression…”
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    The Proteinase-Activated Receptor 2 Is Involved in Nociception by Hoogerwerf, W. A, Zou, L, Shenoy, M, Sun, D, Micci, M. A, Lee-Hellmich, H, Xiao, S. Y, Winston, J. H, Pasricha, P. J

    Published in The Journal of neuroscience (15-11-2001)
    “…The proteinase-activated receptor 2 is expressed on a subset of primary afferent neurons and may participate in the neurogenic component of inflammation. We…”
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    P2X receptor-mediated visceral hyperalgesia in a rat model of chronic visceral hypersensitivity by Xu, G-Y, Shenoy, M, Winston, J H, Mittal, S, Pasricha, P J

    Published in Gut (01-09-2008)
    “…Irritable bowel syndrome (IBS) is a common gastrointestinal disorder characterised by abdominal pain and bloating in association with altered bowel movements…”
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    Neonatal immune challenge followed by adult immune challenge induces epigenetic‐susceptibility to aggravated visceral hypersensitivity by Aguirre, J. E., Winston, J. H., Sarna, S. K.

    Published in Neurogastroenterology and motility (01-09-2017)
    “…Background Abdominal pain is one of the major symptoms of inflammatory Bowel Disease (IBD). The inflammatory mediators released by colon inflammation are known…”
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    Chronic prenatal stress epigenetically modifies spinal cord BDNF expression to induce sex‐specific visceral hypersensitivity in offspring by Winston, J. H., Li, Q., Sarna, S. K.

    Published in Neurogastroenterology and motility (01-05-2014)
    “…Background Irritable bowel syndrome (IBS) is a heterogeneous disorder with abdominal pain as one of the primary symptoms. The etiology of IBS remains unknown…”
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    Auricular vagal nerve stimulation ameliorates burn‐induced gastric dysmotility via sympathetic‐COX‐2 pathways in rats by Li, H., Yin, J., Zhang, Z., Winston, J. H., Shi, X.‐Z., Chen, J. D. Z.

    Published in Neurogastroenterology and motility (01-01-2016)
    “…Background Severe burn injury has been demonstrated to delay gastric emptying. The aim of this study was to investigate effects and cellular mechanisms of…”
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    Electroacupuncture attenuates visceral hyperalgesia and inhibits the enhanced excitability of colon specific sensory neurons in a rat model of irritable bowel syndrome by Xu, G.‐y., Winston, J. H., Chen, J. D. Z.

    Published in Neurogastroenterology and motility (01-12-2009)
    “…The causes of irritable bowel syndrome remain elusive and there are few effective treatments for pain in this syndrome. Electroacupunture (EA) is used…”
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    Ameliorating effects of mirtazapine on visceral hypersensitivity in rats with neonatal colon sensitivity by Yin, J., Wang, W., Winston, J. H., Zhang, R., Chen, J. D. Z.

    Published in Neurogastroenterology and motility (01-09-2010)
    “…Background  The aim was to investigate the effects of mirtazapine on visceral hypersensitivity and gastric emptying in an established rodent model of colonic…”
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    5' flanking sequences of the murine adenosine deaminase gene direct expression of a reporter gene to specific prenatal and postnatal tissues in transgenic mice by Winston, J H, Hanten, G R, Overbeek, P A, Kellems, R E

    Published in The Journal of biological chemistry (05-07-1992)
    “…Adenosine deaminase (ADA), an enzyme of purine metabolism, is highly expressed in four tissues of the mouse: the maternal decidua, the fetal placenta, the…”
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    Trypsin mediates nociception via the proteinase-activated receptor 2: A potentially novel role in pancreatic pain by Hoogerwerf, Willemijntje A., Shenoy, Mohan, Winston, John H., Xiao, Shu-Yuan, He, Zhijun, Pasricha, Pankaj J.

    Published in Gastroenterology (New York, N.Y. 1943) (01-09-2004)
    “…Background & Aims: The pathogenesis of pain in pancreatitis remains poorly understood. We hypothesized that trypsin, a key inflammatory mediator in this…”
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    Diverse Genetic Regulatory Motifs Required for Murine Adenosine Deaminase Gene Expression in the Placenta by Shi, Daqing, Winston, John H., Blackburn, Michael R., Datta, Surjit K., Hanten, Gerri, Kellems, Rodney E.

    Published in The Journal of biological chemistry (24-01-1997)
    “…Murine adenosine deaminase (ADA) is a ubiquitous purine catabolic enzyme whose expression is subject to developmental and tissue-specific regulation. ADA is…”
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    Rat trehalase: cDNA cloning and mRNA expression in adult rat tissues and during intestinal ontogeny by Oesterreicher, T J, Nanthakumar, N N, Winston, J H, Henning, S J

    Published in The American journal of physiology (01-05-1998)
    “…A partial rat trehalase cDNA has been cloned and used to examine trehalase mRNA expression. Northern blotting with total RNA from 11 adult rat tissues showed a…”
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    Regulation of Forestomach-specific Expression of the Murine Adenosine Deaminase Gene by Xu, P A, Winston, J H, Datta, S K, Kellems, R E

    Published in The Journal of biological chemistry (09-04-1999)
    “…The maturation of stratified squamous epithelium of the upper gastrointestinal tract is a highly ordered process of development and differentiation…”
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