Search Results - "Winston, Gary W"
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Application of biomarkers for assessing the biological impact of dredged materials in the Mediterranean: the relationship between antioxidant responses and susceptibility to oxidative stress in the red mullet ( Mullus barbatus)
Published in Marine pollution bulletin (01-09-2002)“…In the period 1997–2000, approximately 1,800,000 m 3 of material dredged from the Port of Leghorn was discharged into a sea dumping site located 14 miles from…”
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Evaluation of the Total Peroxyl Radical-Scavenging Capacity of Flavonoids: Structure−Activity Relationships
Published in Journal of natural products (Washington, D.C.) (01-03-2000)“…The antioxidant activity of a series of flavonoids against peroxyl radicals generated from thermal homolysis of 2,2‘-azobis-amidinopropane was determined by…”
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Total oxidant scavenging capacity (TOSC) of microsomal and cytosolic fractions from Antarctic, Arctic and Mediterranean scallops: differentiation between three potent oxidants
Published in Aquatic toxicology (01-05-2000)“…The enhanced formation of reactive oxygen species (ROS) is a common pathway of toxicity induced by stressful environmental conditions. In polar environments,…”
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Beta carotene and its oxidation products have different effects on microsome mediated binding of benzo[a]pyrene to DNA
Published in Free radical biology & medicine (1999)“…The effects of β-carotene (βC) and its oxidation products on the binding of benzo[a]pyrene (BaP) metabolites to calf thymus DNA was investigated in the…”
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Quantification of Total Oxidant Scavenging Capacity of Antioxidants for Peroxynitrite, Peroxyl Radicals, and Hydroxyl Radicals
Published in Toxicology and applied pharmacology (15-04-1999)“…We have extended the application of our previously reported total oxidant scavenging capacity (TOSC) assay (Winstonet al., Free Radical Biol. Med.24, 480–493,…”
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Integrating enzymatic responses to organic chemical exposure with total oxyradical absorbing capacity and dna damage in the european eel Anguilla anguilla
Published in Environmental toxicology and chemistry (01-09-2003)“…In this work, susceptibility to oxidative stress was analyzed under laboratory conditions in the European eel Anguilla anguilla. Eels were treated with…”
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Antioxidants and total oxyradical scavenging capacity during grass shrimp, Palaemonetes pugio, embryogenesis
Published in Comparative biochemistry and physiology. Toxicology & pharmacology (01-12-2004)“…During embryogenesis in grass shrimp the capacity to scavenge oxyradicals increased as measured by the Total Oxyradical Scavenging Capacity (TOSC) assay. The…”
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8
Oxygen radical production in the sea anemone Anthopleura elegantissima and its endosymbiotic algae
Published in Journal of experimental biology (01-07-1992)“…ABSTRACT Host animals in algal-invertebrate endosymbiotic associations are exposed to photosynthetically generated hyperoxia while in sunlight, conditions…”
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A Rapid Gas Chromatographic Assay for Determining Oxyradical Scavenging Capacity of Antioxidants and Biological Fluids
Published in Free radical biology & medicine (01-02-1998)“…Herein, we report a new, rapid,and reliable method for measuring the protective antioxidant potential of pure antioxidant solutions or biological tissues…”
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Antioxidant defenses in killifish ( Fundulus heteroclitus) exposed to contaminated sediments and model prooxidants: short-term and heritable responses
Published in Aquatic toxicology (10-12-2003)“…A population of killifish ( Fundulus heteroclitus) inhabiting a Superfund site on the Elizabeth River (VA, USA) is tolerant of the acute toxicity of the…”
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Induction Time Course of Cytochromes P450 by Phenobarbital and 3-Methylcholanthrene Pretreatment in Liver Microsomes of Alligator mississippiensis
Published in Biochemical pharmacology (01-05-1998)“…Alligator mississippiensis has at least two classes of inducible hepatic microsomal cytochromes P450 (CYP): (1) those induced by 3-methylcholanthrene (3MC),…”
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Enzymatic and Nonenzymatic Production of Free Radicals from the Carcinogens 4-Nitroquinoline N-Oxide and 4-Hydroxylaminoquinoline N-Oxide
Published in Chemical research in toxicology (01-05-1999)“…The anion radicals of 4-nitroquinoline N-oxide (4-NQO) and 4-nitrosoquinoline N-oxide (4-NOQO) carcinogens were detected and characterized by electron spin…”
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13
Oxyradical scavenging capacity by the S9 fraction of Hexagenia spp. nymphs from the Western Basin of Lake Erie: neutralisation of three potent oxidants
Published in Chemistry and ecology (01-04-2010)“…Oxidative stress is a general response of aquatic organisms to environmental contamination. Metals and organic compounds capable of redox cycling cause…”
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Sex-related responses to oxidative stress in primary cultured hepatocytes of European flounder ( Platichthys flesus L. )
Published in Aquatic toxicology (01-04-2001)“…Effects of oxidative stress induced by xenobiotic compounds were studied in primary cultures of isolated hepatocytes of immature European flounder (…”
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Reactions of Peroxynitrite with Aldehydes as Probes for the Reactive Intermediates Responsible for Biological Nitration
Published in Chemical research in toxicology (01-12-1997)“…We have examined the reactions of peroxynitrite with short-chain aliphatic aldehydes to model the reaction of the peroxynitrite anion (ONOO-) with CO2…”
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Spectral analysis and catalytic activities of the microsomal mixed-function oxidase system of the sea anemone (phylum: Cnidaria)
Published in Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology (01-11-1998)“…Cnidarians are primarily marine organisms with a wide and diverse habitat worldwide. Previous studies from our laboratory demonstrated the presence of proteins…”
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Hepatic monooxygenase induction and promutagen activation in channel catfish from a contaminated river basin
Published in Ecotoxicology and environmental safety (01-12-1988)“…To better understand the etiology of cancer in fish from polluted waters, the impact of environmental contaminants on xenobiotic metabolism of channel catfish…”
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novel substrate for yeast alcohol dehydrogenase-p-nitroso-N,N-dimethylaniline
Published in Biotechnology letters (2002)“…Yeast alcohol dehydrogenase (EC 1.1.1.1) catalyzes the novel reduction of p-nitroso-N,N-dimethylaniline with NADH as a cofactor. Apparent kinetic constants for…”
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Aldehyde dismutase activity of yeast alcohol dehydrogenase
Published in Biotechnology letters (01-03-1999)“…Yeast alcohol dehydrogenase (EC 1.1.1.1) is able to catalyze the oxidation of acetaldehyde by NAD+ with a concomitant formation of ethanol, at pH 8.8 and pH…”
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Bioorganic Mechanisms of the Formation of Free Radicals Catalyzed by Glucose Oxidase
Published in Bioorganic chemistry (01-04-2002)“…In this communication, we have described the activation of several xenobiotics by glucose oxidase from Aspergillus niger. The following compounds are readily…”
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