Search Results - "Winston, Brent"

Safety of cell therapy with mesenchymal stromal cells (SafeCell): a systematic review and meta-analysis of clinical trials by Lalu, Manoj M, McIntyre, Lauralyn, Pugliese, Christina, Fergusson, Dean, Winston, Brent W, Marshall, John C, Granton, John, Stewart, Duncan J

“…Mesenchymal stromal cells (MSCs, "adult stem cells") have been widely used experimentally in a variety of clinical contexts. There is interest in using these…”
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Metabolomics as a Novel Approach for Early Diagnosis of Pediatric Septic Shock and Its Mortality by MICKIEWICZ, Beata, VOGEL, Hans J, WONG, Hector R, WINSTON, Brent W

“…Septic shock is a significant cause of morbidity and mortality in the pediatric population. Early recognition of septic shock and appropriate treatment…”
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Integration of metabolic and inflammatory mediator profiles as a potential prognostic approach for septic shock in the intensive care unit by Mickiewicz, Beata, Tam, Patrick, Jenne, Craig N, Leger, Caroline, Wong, Josee, Winston, Brent W, Doig, Christopher, Kubes, Paul, Vogel, Hans J

“…Septic shock is a major life-threatening condition in critically ill patients and it is well known that early recognition of septic shock and expedient…”
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Cellular Immunotherapy for Septic Shock. A Phase I Clinical Trial by McIntyre, Lauralyn A, Stewart, Duncan J, Mei, Shirley H J, Courtman, David, Watpool, Irene, Granton, John, Marshall, John, Dos Santos, Claudia, Walley, Keith R, Winston, Brent W, Schlosser, Kenny, Fergusson, Dean A

“…In septic animal models mesenchymal stem (stromal) cells (MSCs) modulate inflammation, enhance tissue repair and pathogen clearance, and reduce death. To…”
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Metabolomics in severe traumatic brain injury: a scoping review by Fedoruk, Riley Page, Lee, Chel Hee, Banoei, Mohammad Mehdi, Winston, Brent W

“…Abstract Background Diagnosis and prognostication of severe traumatic brain injury (sTBI) continue to be problematic despite years of research efforts. There…”
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Using metabolomics to predict severe traumatic brain injury outcome (GOSE) at 3 and 12 months by Banoei, Mohammad M, Lee, Chel Hee, Hutchison, James, Panenka, William, Wellington, Cheryl, Wishart, David S, Winston, Brent W

“…Prognostication is very important to clinicians and families during the early management of severe traumatic brain injury (sTBI), however, there are no gold…”
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Burn Wound Infections by CHURCH, Deirdre, ELSAYED, Sameer, REID, Owen, WINSTON, Brent, LINDSAY, Robert

“…Classifications Services CMR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Effects of Mesenchymal Stem Cell Treatment on Systemic Cytokine Levels in a Phase 1 Dose Escalation Safety Trial of Septic Shock Patients by Schlosser, Kenny, Wang, Jia-Pey, dos Santos, Claudia, Walley, Keith R., Marshall, John, Fergusson, Dean A., Winston, Brent W., Granton, John, Watpool, Irene, Stewart, Duncan J., McIntyre, Lauralyn A., Mei, Shirley H. J.

“…OBJECTIVES:Cellular Immunotherapy for Septic Shock is the first-in-human clinical trial evaluating allogeneic mesenchymal stem/stromal cells in septic shock…”
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On becoming a clinician-scientist: The importance of mentorship and role models by Winston, Brent W

“…Brent graduated from medicine (with distinction) from the University of Alberta in 1984, and subsequently trained in Internal Medicine at the University of…”
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Plasma lipid profiling for the prognosis of 90-day mortality, in-hospital mortality, ICU admission, and severity in bacterial community-acquired pneumonia (CAP) by Banoei, Mohammad M, Vogel, Hans J, Weljie, Aalim M, Yende, Sachin, Angus, Derek C, Winston, Brent W

“…Pneumonia is the most common cause of mortality from infectious diseases, the second leading cause of nosocomial infection, and the leading cause of mortality…”
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Plasma metabolomics for the diagnosis and prognosis of H1N1 influenza pneumonia by Banoei, Mohammad M, Vogel, Hans J, Weljie, Aalim M, Kumar, Anand, Yende, Sachin, Angus, Derek C, Winston, Brent W

“…Metabolomics is a tool that has been used for the diagnosis and prognosis of specific diseases. The purpose of this study was to examine if metabolomics could…”
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Metabolomic and metallomic profile differences between Veterans and Civilians with Pulmonary Sarcoidosis by Banoei, Mohammad Mehdi, Iupe, Isabella, Bazaz, Reza Dowlatabadi, Campos, Michael, Vogel, Hans J., Winston, Brent W., Mirsaeidi, Mehdi

“…Sarcoidosis is a disorder characterized by granulomatous inflammation of unclear etiology. In this study we evaluated whether veterans with sarcoidosis…”
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Cell therapy with intravascular administration of mesenchymal stromal cells continues to appear safe: An updated systematic review and meta-analysis by Thompson, Mary, Mei, Shirley H.J., Wolfe, Dianna, Champagne, Josée, Fergusson, Dean, Stewart, Duncan J., Sullivan, Katrina J., Doxtator, Emily, Lalu, Manoj, English, Shane W., Granton, John, Hutton, Brian, Marshall, John, Maybee, Alies, Walley, Keith R., Santos, Claudia Dos, Winston, Brent, McIntyre, Lauralyn

“…Characterization of the mesenchymal stromal cell (MSC) safety profile is important as this novel therapy continues to be evaluated in clinical trials for…”
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Evolution of ARDS biomarkers: Will metabolomics be the answer? by Metwaly, Sayed, Cote, Andreanne, Donnelly, Sarah J, Banoei, Mohammad M, Mourad, Ahmed I, Winston, Brent W

“…To date, there is no clinically agreed-upon diagnostic test for acute respiratory distress syndrome (ARDS): the condition is still diagnosed on the basis of a…”
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Longitudinal Plasma Proteomics Analysis Reveals Novel Candidate Biomarkers in Acute COVID-19 by Mohammed, Yassene, Goodlett, David R, Cheng, Matthew P, Vinh, Donald C, Lee, Todd C, Mcgeer, Allison, Sweet, David, Tran, Karen, Lee, Terry, Murthy, Srinivas, Boyd, John H, Singer, Joel, Walley, Keith R, Patrick, David M, Quan, Curtis, Ismail, Sara, Amar, Laetitia, Pal, Aditya, Bassawon, Rayhaan, Fesdekjian, Lara, Gou, Karine, Lamontagne, Francois, Marshall, John, Haljan, Greg, Fowler, Robert, Winston, Brent W, Russell, James A

“…The host response to COVID-19 pathophysiology over the first few days of infection remains largely unclear, especially the mechanisms in the blood compartment…”
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NMR-based metabolomic profiling can differentiate follicular lymphoma from benign lymph node tissues and may be predictive of outcome by Banoei, Mohammad Mehdi, Mahé, Etienne, Mansoor, Adnan, Stewart, Douglas, Winston, Brent W., Habibi, Hamid R., Shabani-Rad, Meer-Taher

“…Follicular lymphoma (FL) is a cancer of B-cells, representing the second most common type of non-Hodgkin lymphoma and typically diagnosed at advanced stage in…”
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Targeting inflammatory monocytes in sepsis-associated encephalopathy and long-term cognitive impairment by Andonegui, Graciela, Zelinski, Erin L, Schubert, Courtney L, Knight, Derrice, Craig, Laura A, Winston, Brent W, Spanswick, Simon C, Petri, Björn, Jenne, Craig N, Sutherland, Janice C, Nguyen, Rita, Jayawardena, Natalie, Kelly, Margaret M, Doig, Christopher J, Sutherland, Robert J, Kubes, Paul

“…Sepsis-associated encephalopathy manifesting as delirium is a common problem in critical care medicine. In this study, patients that had delirium due to sepsis…”
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Metabolomics: Applications and Promise in Mycobacterial Disease by Mirsaeidi, Mehdi, Banoei, Mohammad Mehdi, Winston, Brent W, Schraufnagel, Dean E

“…Until recently, the study of mycobacterial diseases was trapped in culture-based technology that is more than a century old. The use of nucleic acid…”
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A B1a-natural IgG-neutrophil axis is impaired in viral- and steroid-associated aspergillosis by Sarden, Nicole, Sinha, Sarthak, Potts, Kyle G, Pernet, Erwan, Hiroki, Carlos H, Hassanabad, Mortaza F, Nguyen, Angela P, Lou, Yuefei, Farias, Raquel, Winston, Brent W, Bromley, Amy, Snarr, Brendan D, Zucoloto, Amanda Z, Andonegui, Graciela, Muruve, Daniel A, McDonald, Braedon, Sheppard, Donald C, Mahoney, Douglas J, Divangahi, Maziar, Rosin, Nicole, Biernaskie, Jeff, Yipp, Bryan G

“…The lung naturally resists ( ) in healthy individuals, but multiple conditions can disrupt this resistance, leading to lethal invasive infections. Core…”
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Endotyping in ARDS: one step forward in precision medicine by Côté, Andréanne, Lee, Chel Hee, Metwaly, Sayed M, Doig, Christopher J, Andonegui, Graciela, Yipp, Bryan G, Parhar, Ken Kuljit S, Winston, Brent W

“…The Berlin definition of acute respiratory distress syndrome (ARDS) includes only clinical characteristics. Understanding unique patient pathobiology may allow…”
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