Search Results - "Winslow, John W."
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Role of antibodies, inflammatory markers, and echocardiographic findings in postacute cardiopulmonary symptoms after SARS-CoV-2 infection
Published in JCI insight (23-05-2022)“…Shortness of breath, chest pain, and palpitations occur as postacute sequelae of COVID-19, but whether symptoms are associated with echocardiographic…”
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Markers of Immune Activation and Inflammation in Individuals With Postacute Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 Infection
Published in The Journal of infectious diseases (01-12-2021)“…Abstract Background The biological processes associated with postacute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection…”
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Chronic viral coinfections differentially affect the likelihood of developing long COVID
Published in The Journal of clinical investigation (01-02-2023)“…BACKGROUNDThe presence and reactivation of chronic viral infections, such as EBV, CMV, and HIV, have been proposed as potential contributors to long COVID…”
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Postacute sequelae and adaptive immune responses in people with HIV recovering from SARS-COV-2 infection
Published in AIDS (London) (01-10-2022)“…Limited data are available on the long-term clinical and immunologic consequences of SARS-CoV-2 infection in people with HIV (PWH). We measured…”
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Reduced Exercise Capacity, Chronotropic Incompetence, and Early Systemic Inflammation in Cardiopulmonary Phenotype Long Coronavirus Disease 2019
Published in The Journal of infectious diseases (31-08-2023)“…Abstract Background Mechanisms underlying persistent cardiopulmonary symptoms after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection…”
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Early biological markers of post-acute sequelae of SARS-CoV-2 infection
Published in Nature communications (29-08-2024)“…To understand the roles of acute-phase viral dynamics and host immune responses in post-acute sequelae of SARS-CoV-2 infection (PASC), we enrolled 136…”
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Plasma Markers of Neurologic Injury and Inflammation in People With Self-Reported Neurologic Postacute Sequelae of SARS-CoV-2 Infection
Published in Neurology : neuroimmunology & neuroinflammation (01-09-2022)“…The biologic mechanisms underlying neurologic postacute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (PASC) are…”
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Markers of fungal translocation are elevated during post-acute sequelae of SARS-CoV-2 and induce NF-κB signaling
Published in JCI insight (08-08-2022)“…Long COVID, a type of post-acute sequelae of SARS-CoV-2 (PASC), has been associated with sustained elevated levels of immune activation and inflammation…”
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Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes
Published in Nature (London) (04-08-1988)“…Muscarinic acetylcholine receptors (mAChRs), like many other neurotransmitter and hormone receptors, transduce agonist signals by activating G proteins to…”
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Evaluation of Severe Acute Respiratory Syndrome Coronavirus 2 Nucleocapsid Antigen in the Blood as a Diagnostic Test for Infection and Infectious Viral Shedding
Published in Open forum infectious diseases (01-11-2022)“…SARS-CoV-2 nucleocapsid antigen can be detected in plasma, but little is known about its performance as a diagnostic test for acute SARS-CoV-2 infection or…”
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Markers of fungal translocation are elevated during post-acute sequelae of SARS-CoV-2 and induce NF-κB signaling
Published in JCI insight (22-09-2022)Get full text
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Protein targeting in the analysis of learning and memory : a potential alternative to gene targeting
Published in Experimental brain research (01-11-1998)“…Gene targeting using homologous recombination in embryonic stem (ES) cells offers unprecedented precision with which one may manipulate single genes and…”
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Cloning of AL-1, a ligand for an Eph-related tyrosine kinase receptor involved in axon bundle formation
Published in Neuron (Cambridge, Mass.) (1995)“…REK7 is an Eph-related tyrosine kinase receptor expressed exclusively in the nervous system, predominantly in hippocampus and cortex. A soluble REK7-IgG fusion…”
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Widespread Expression of BDNF But Not NT3 by Target Areas of Basal Forebrain Cholinergic Neurons
Published in Science (American Association for the Advancement of Science) (12-10-1990)“…Brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT3) are homologs of the well-known neurotrophic factor nerve growth factor. The three members of…”
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AL-1-induced Growth Cone Collapse of Rat Cortical Neurons is Correlated with REK7 Expression and Rearrangement of the Actin Cytoskeleton
Published in The European journal of neuroscience (01-01-1997)“…Previous experiments identified AL‐1 as a glycosylphosphatidylinositol (GPI)‐linked ligand for the Eph‐related receptor, REK7, and showed that a REK7‐IgG…”
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Neurotrophin-3 reverses experimental cisplatin-induced peripheral sensory neuropathy
Published in Annals of neurology (01-07-1995)“…Cisplatin, a widely used chemotherapeutic agent, induces a sensory neuropathy with selective loss of vibration sense and proprioception. Here we demonstrate…”
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Abstract 3612: Elevated TGFa levels in chronic mylogenous leukemia (CML) patient plasma measured by a highly sensitive single molecule array immunoassay
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Introduction: Recent reports suggest that cytokine and growth factor profiling are prognostic in myelodisplasias and CML. TGF-α and IL-6 plasma levels…”
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Functionally distinct G proteins selectively couple different receptors to PI hydrolysis in the same cell
Published in Cell (10-02-1989)“…The number of G proteins identified by molecular cloning exceeds the number of known G protein functions. Here we show that a cell can possess multiple G…”
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An M2 Muscarinic Receptor Subtype Coupled to Both Adenylyl Cyclase and Phosphoinositide Turnover
Published in Science (American Association for the Advancement of Science) (30-10-1987)“…To investigate whether a particular receptor subtype can be coupled to multiple effector systems, recombinant M2 muscarinic receptors were expressed in cells…”
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Primary structure and biochemical properties of an M2 muscarinic receptor
Published in Science (American Association for the Advancement of Science) (01-05-1987)“…A partial amino acid sequence obtained for porcine atrial muscarinic acetylcholine receptor was used to isolate complementary DNA clones containing the…”
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