Search Results - "Winslow, John W."

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    Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes by Peralta, Ernest G, Ashkenazi, Avi, Winslow, John W, Ramachandran, J, Capon, Daniel J

    Published in Nature (London) (04-08-1988)
    “…Muscarinic acetylcholine receptors (mAChRs), like many other neurotransmitter and hormone receptors, transduce agonist signals by activating G proteins to…”
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    Journal Article
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    Protein targeting in the analysis of learning and memory : a potential alternative to gene targeting by GERLAI, R, WILLIAMS, S. P, CAIRNS, B, VAN BRUGGEN, N, MORAN, P, SHIH, A, CARAS, I, SAUER, H, PHILLIPS, H. S, WINSLOW, J. W

    Published in Experimental brain research (01-11-1998)
    “…Gene targeting using homologous recombination in embryonic stem (ES) cells offers unprecedented precision with which one may manipulate single genes and…”
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    Conference Proceeding Journal Article
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    Cloning of AL-1, a ligand for an Eph-related tyrosine kinase receptor involved in axon bundle formation by Winslow, John W, Moran, Paul, Valverde, Janet, Shih, Ai, Yuan, Jean O, Wong, Suzy C, Tsai, Siao Ping, Goddard, Audrey, Henzel, William J, Hefti, Franz, Beck, Klaus D, Caras, Ingrid W

    Published in Neuron (Cambridge, Mass.) (1995)
    “…REK7 is an Eph-related tyrosine kinase receptor expressed exclusively in the nervous system, predominantly in hippocampus and cortex. A soluble REK7-IgG fusion…”
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    Journal Article
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    Widespread Expression of BDNF But Not NT3 by Target Areas of Basal Forebrain Cholinergic Neurons by Phillips, Heidi S., Hains, Jeanne M., Laramee, Gary R., Rosenthal, Arnon, Winslow, John W.

    “…Brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT3) are homologs of the well-known neurotrophic factor nerve growth factor. The three members of…”
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    Journal Article
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    AL-1-induced Growth Cone Collapse of Rat Cortical Neurons is Correlated with REK7 Expression and Rearrangement of the Actin Cytoskeleton by Meima, Leonie, Kljavin, Ivar J., Moran, Paul, Shih, Ai, Winslow, John W., Caras, Ingrid W.

    Published in The European journal of neuroscience (01-01-1997)
    “…Previous experiments identified AL‐1 as a glycosylphosphatidylinositol (GPI)‐linked ligand for the Eph‐related receptor, REK7, and showed that a REK7‐IgG…”
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    Journal Article
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    Neurotrophin-3 reverses experimental cisplatin-induced peripheral sensory neuropathy by Gao, W Q, Dybdal, N, Shinsky, N, Murnane, A, Schmelzer, C, Siegel, M, Keller, G, Hefti, F, Phillips, H S, Winslow, J W

    Published in Annals of neurology (01-07-1995)
    “…Cisplatin, a widely used chemotherapeutic agent, induces a sensory neuropathy with selective loss of vibration sense and proprioception. Here we demonstrate…”
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    Journal Article
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    Abstract 3612: Elevated TGFa levels in chronic mylogenous leukemia (CML) patient plasma measured by a highly sensitive single molecule array immunoassay by Chenna, Ahmed, Cai, Li, Petropoulos, Christos, Winslow, John W.

    Published in Cancer research (Chicago, Ill.) (01-07-2018)
    “…Abstract Introduction: Recent reports suggest that cytokine and growth factor profiling are prognostic in myelodisplasias and CML. TGF-α and IL-6 plasma levels…”
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    Journal Article
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    Functionally distinct G proteins selectively couple different receptors to PI hydrolysis in the same cell by Ashkenazi, A, Peralta, E G, Winslow, J W, Ramachandran, J, Capon, D J

    Published in Cell (10-02-1989)
    “…The number of G proteins identified by molecular cloning exceeds the number of known G protein functions. Here we show that a cell can possess multiple G…”
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    Journal Article
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    An M2 Muscarinic Receptor Subtype Coupled to Both Adenylyl Cyclase and Phosphoinositide Turnover by Ashkenazi, Avi, Winslow, John W., Peralta, Ernest G., Peterson, Gary L., Schimerlik, Michael I., Capon, Daniel J., Ramachandran, Janakiraman

    “…To investigate whether a particular receptor subtype can be coupled to multiple effector systems, recombinant M2 muscarinic receptors were expressed in cells…”
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    Journal Article
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    Primary structure and biochemical properties of an M2 muscarinic receptor by PERALTA, E. G, WINSLOW, J. W, PETERSON, G. L, SMITH, D. H, ASHKENAZI, A, RAMACHANDRAN, J, SCHIMERLIK, M. I, CAPON, D. J

    “…A partial amino acid sequence obtained for porcine atrial muscarinic acetylcholine receptor was used to isolate complementary DNA clones containing the…”
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    Journal Article