Search Results - "Winskill, Peter"
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Estimates of the severity of coronavirus disease 2019: a model-based analysis
Published in The Lancet infectious diseases (01-06-2020)“…In the face of rapidly changing data, a range of case fatality ratio estimates for coronavirus disease 2019 (COVID-19) have been produced that differ…”
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Estimated impact of RTS,S/AS01 malaria vaccine allocation strategies in sub-Saharan Africa: A modelling study
Published in PLoS medicine (30-11-2020)“…The RTS,S/AS01 vaccine against Plasmodium falciparum malaria infection completed phase III trials in 2014 and demonstrated efficacy against clinical malaria of…”
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Systematic review of indoor residual spray efficacy and effectiveness against Plasmodium falciparum in Africa
Published in Nature communications (26-11-2018)“…Indoor residual spraying (IRS) is an important part of malaria control. There is a growing list of insecticide classes; pyrethroids remain the principal…”
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Estimating the burden of severe malarial anaemia and access to hospital care in East Africa
Published in Nature communications (14-09-2023)“…Severe malarial anaemia can be fatal if not promptly treated. Hospital studies may under-represent the true burden because cases often occur in settings with…”
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The potential of gene drives in malaria vector species to control malaria in African environments
Published in Nature communications (17-10-2024)“…Gene drives are a promising means of malaria control with the potential to cause sustained reductions in transmission. In real environments, however, their…”
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Prioritizing the scale-up of interventions for malaria control and elimination
Published in Malaria journal (08-04-2019)“…A core set of intervention and treatment options are recommended by the World Health Organization for use against falciparum malaria. These are treatment,…”
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Long-term vaccination strategies to mitigate the impact of SARS-CoV-2 transmission: A modelling study
Published in PLoS medicine (28-11-2023)“…Vaccines have reduced severe disease and death from Coronavirus Disease 2019 (COVID-19). However, with evidence of waning efficacy coupled with continued…”
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Estimating long-term vaccine effectiveness against SARS-CoV-2 variants: a model-based approach
Published in Nature communications (19-07-2023)“…With the ongoing evolution of the SARS-CoV-2 virus updated vaccines may be needed. We fitted a model linking immunity levels and protection to vaccine…”
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Strategies for tackling Taenia solium taeniosis/cysticercosis: A systematic review and comparison of transmission models, including an assessment of the wider Taeniidae family transmission models
Published in PLoS neglected tropical diseases (01-04-2019)“…The cestode Taenia solium causes the neglected (zoonotic) tropical disease cysticercosis, a leading cause of preventable epilepsy in endemic low and…”
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Analysis of the potential for a malaria vaccine to reduce gaps in malaria intervention coverage
Published in Malaria journal (17-11-2021)“…The RTS,S/AS01 malaria vaccine is currently being evaluated in a cluster-randomized pilot implementation programme in three African countries. This study seeks…”
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Modeling resource allocation strategies for insecticide-treated bed nets to achieve malaria eradication
Published in eLife (08-02-2024)“…Large reductions in the global malaria burden have been achieved, but plateauing funding poses a challenge for progressing towards the ultimate goal of malaria…”
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Health inequities and clustering of fever, acute respiratory infection, diarrhoea and wasting in children under five in low- and middle-income countries: a Demographic and Health Surveys analysis
Published in BMC medicine (24-06-2021)“…Pneumonia, diarrhoea and malaria are responsible for over one third of all deaths in children under the age of 5 years in low and middle sociodemographic index…”
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Projected health impact of post-discharge malaria chemoprevention among children with severe malarial anaemia in Africa
Published in Nature communications (25-01-2023)“…Children recovering from severe malarial anaemia (SMA) remain at high risk of readmission and death after discharge from hospital. However, a recent trial…”
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The US President's Malaria Initiative, Plasmodium falciparum transmission and mortality: A modelling study
Published in PLoS medicine (21-11-2017)“…Although significant progress has been made in reducing malaria transmission globally in recent years, a large number of people remain at risk and hence the…”
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Dispersal of Engineered Male Aedes aegypti Mosquitoes
Published in PLoS neglected tropical diseases (01-11-2015)“…Aedes aegypti, the principal vector of dengue fever, have been genetically engineered for use in a sterile insect control programme. To improve our…”
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Modelling the impact of vaccine hesitancy in prolonging the need for Non-Pharmaceutical Interventions to control the COVID-19 pandemic
Published in Communications medicine (10-02-2022)“…Background Vaccine hesitancy – a delay in acceptance or refusal of vaccines despite availability – has the potential to threaten the successful roll-out of…”
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False-negative malaria rapid diagnostic test results and their impact on community-based malaria surveys in sub-Saharan Africa
Published in BMJ global health (01-07-2019)“…Surveillance and diagnosis of Plasmodium falciparum malaria relies predominantly on rapid diagnostic tests (RDT). However, false-negative (FN) RDT results are…”
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Global variation in force-of-infection trends for human Taenia solium taeniasis/cysticercosis
Published in eLife (19-08-2022)“…Infection by Taenia solium poses a major burden across endemic countries. The World Health Organization (WHO) 2021–2030 Neglected Tropical Diseases roadmap has…”
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Modelling population-level impact to inform target product profiles for childhood malaria vaccines
Published in BMC medicine (13-07-2018)“…The RTS,S/AS01 vaccine for Plasmodium falciparum malaria demonstrated moderate efficacy in 5-17-month-old children in phase 3 trials, and from 2018, the…”
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Malaria risk factors in north-east Tanzania
Published in Malaria journal (20-04-2011)“…Understanding the factors which determine a household's or individual's risk of malaria infection is important for targeting control interventions at all…”
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