Search Results - "Wins, P"

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    Thiamine triphosphate and thiamine triphosphatase activities: from bacteria to mammals by Makarchikov, A F, Lakaye, B, Gulyai, I E, Czerniecki, J, Coumans, B, Wins, P, Grisar, T, Bettendorff, L

    “…In most organisms, the main form of thiamine is the coenzyme thiamine diphosphate. Thiamine triphosphate (ThTP) is also found in low amounts in most vertebrate…”
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  2. 2

    Mechanism of thiamine transport in neuroblastoma cells. Inhibition of a high affinity carrier by sodium channel activators and dependence of thiamine uptake on membrane potential and intracellular ATP by BETTENDORFF, L, WINS, P

    Published in The Journal of biological chemistry (20-05-1994)
    “…Nerve cells are particularly sensitive to thiamine deficiency. We studied thiamine transport in mouse neuroblastoma (Neuro 2a) cells. At low external…”
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    Neuronal localization of the 25-kDa specific thiamine triphosphatase in rodent brain by Czerniecki, J, Chanas, G, Verlaet, M, Bettendorff, L, Makarchikov, A.F, Leprince, P, Wins, P, Grisar, T, Lakaye, B

    Published in Neuroscience (2004)
    “…Thiamine triphosphate (ThTP) is found in small amounts in most organisms from bacteria to mammals, but little is known about its physiological role. In…”
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  4. 4

    Thiamine deficiency in cultured neuroblastoma cells: effect on mitochondrial function and peripheral benzodiazepine receptors by Bettendorff, L, Goessens, G, Sluse, F, Wins, P, Bureau, M, Laschet, J, Grisar, T

    Published in Journal of neurochemistry (01-05-1995)
    “…When neuroblastoma cells were transferred to a medium of low (6 nM) thiamine concentration, a 16-fold decrease in total intracellular thiamine content occurred…”
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    Paradoxical sleep deprivation increases the content of glutamate and glutamine in rat cerebral cortex by Bettendorff, L, Sallanon-Moulin, M, Touret, M, Wins, P, Margineanu, I, Schoffeniels, E

    Published in Sleep (New York, N.Y.) (01-01-1996)
    “…We investigated the influence of the sleep/waking cycle, the effects of paradoxical sleep deprivation (PSD) and of the vigilance-promoting drug modafinil on…”
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  6. 6

    Determination of thiamin and its phosphate esters in cultured neurons and astrocytes using an ion-pair reversed-phase high-performance liquid chromatographic method by Bettendorff, L, Peeters, M, Jouan, C, Wins, P, Schoffeniels, E

    Published in Analytical biochemistry (01-10-1991)
    “…A sensitive method, based on fluorescence detection, for the determination of thiamin derivatives after precolumn derivatization is described. The separation…”
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  7. 7

    Metabolism of thiamine triphosphate in rat brain: correlation with chloride permeability by Bettendorff, L, Peeters, M, Wins, P, Schoffeniels, E

    Published in Journal of neurochemistry (01-02-1993)
    “…Our results show that a net synthesis of thiamine triphosphate (TTP) can be demonstrated in vitro using rat brain extracts. The total homogenate was…”
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  8. 8

    Thiamine deficiency--induced partial necrosis and mitochondrial uncoupling in neuroblastoma cells are rapidly reversed by addition of thiamine by Bettendorff, L, Sluse, F, Goessens, G, Wins, P, Grisar, T

    Published in Journal of neurochemistry (01-11-1995)
    “…Culture of neuroblastoma cells in a medium of low-thiamine concentration (6 nM) and in the presence of the transport inhibitor amprolium leads to the…”
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  9. 9

    Thiamin and derivatives as modulators of rat brain chloride channels by Bettendorff, L, Hennuy, B, Wins, P, Schoffeniels, E

    Published in Neuroscience (01-02-1993)
    “…Several membrane fractions were prepared from rat brain by differential and sucrose density gradient centrifugation. Most fractions took up 36Cl- rapidly at a…”
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  10. 10

    Low Thiamine Diphosphate Levels in Brains of Patients with Frontal Lobe Degeneration of the Non‐Alzheimer's Type by Bettendorff, L., Mastrogiacomo, F., Wins, P., Kish, S. J., Grisar, T., Ball, M. J.

    Published in Journal of neurochemistry (01-11-1997)
    “…: We compared the thiamine and thiamine phosphate contents in the frontal, temporal, parietal, and occipital cortex of six patients with frontal lobe…”
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  11. 11

    An Atypical Anion Transporter Functioning at Acid pH in Neuroblastoma Cells by Bettendorff, L., Margineanu, I., Wins, P., Grisar, T.

    “…At pH 7.4, 36Cl − uptake by neuroblastoma cells was Na +-independent, saturable and blocked by submicromolar concentrations of DIDS. This suggests that at this…”
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    Thiamine Triphosphate, a New Signal Required for Optimal Growth of Escherichia coli during Amino Acid Starvation by Lakaye, Bernard, Wirtzfeld, Barbara, Wins, Pierre, Grisar, Thierry, Bettendorff, Lucien

    Published in The Journal of biological chemistry (23-04-2004)
    “…Thiamine triphosphate (ThTP) is present in low amounts in most organisms from bacteria to humans, but its biological role remains unknown. Escherichia coli…”
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    A general method for the chemical synthesis of gamma-P-32-labeled or unlabeled nucleoside 5 '-triphosphates and thiamine triphosphate by Bettendorff, Lucien, Nghiem, Hoang O, Wins, Pierre, Lakaye, Bernard

    Published 15-11-2003
    “…Several methods for the chemical synthesis of gamma-P-32-labeled and unlabeled nucleoside 5'-triphosphates and thiamine triphosphate (ThTP) have been…”
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  16. 16

    A general method for the chemical synthesis of gamma - super(32)P-labeled or unlabeled nucleoside 5 super(')-triphosphates and thiamine triphosphate by Bettendorff, L, Nghiem, H-O, Wins, P, Lakaye, B

    Published in Analytical biochemistry (01-11-2003)
    “…Several methods for the chemical synthesis of gamma - super(32)P-labeled and unlabeled nucleoside 5 super(')-triphosphates and thiamine triphosphate (ThTP)…”
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  17. 17

    Pig tissues express a catalytically inefficient 25-kDa thiamine triphosphatase: Insight in the catalytic mechanisms of this enzyme by Szyniarowski, Piotr, Lakaye, Bernard, Czerniecki, Jan, Makarchikov, Alexander F., Wins, Pierre, Margineanu, Ilca, Coumans, Bernard, Grisar, Thierry, Bettendorff, Lucien

    Published in Biochimica et biophysica acta (30-08-2005)
    “…Thiamine triphosphate (ThTP) is found in most organisms and may be an intracellular signal molecule produced in response to stress. We have recently cloned the…”
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    Molecular Characterization of a Specific Thiamine Triphosphatase Widely Expressed in Mammalian Tissues by Lakaye, Bernard, Makarchikov, Alexander F., Antunes, Adelio Fernandes, Zorzi, Willy, Coumans, Bernard, De Pauw, Edwin, Wins, Pierre, Grisar, Thierry, Bettendorff, Lucien

    Published in The Journal of biological chemistry (19-04-2002)
    “…Thiamine triphosphate (ThTP) is found at low concentrations in most animal tissues, and recent data suggest that it may act as a phosphate donor for the…”
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