Search Results - "Winnok H. De, Vos"

Photothermal nanofibres enable safe engineering of therapeutic cells by Xiong, Ranhua, Hua, Dawei, Van Hoeck, Jelter, Berdecka, Dominika, Léger, Laurens, De Munter, Stijn, Fraire, Juan C., Raes, Laurens, Harizaj, Aranit, Sauvage, Félix, Goetgeluk, Glenn, Pille, Melissa, Aalders, Jeffrey, Belza, Joke, Van Acker, Thibaut, Bolea-Fernandez, Eduardo, Si, Ting, Vanhaecke, Frank, De Vos, Winnok H., Vandekerckhove, Bart, van Hengel, Jolanda, Raemdonck, Koen, Huang, Chaobo, De Smedt, Stefaan C., Braeckmans, Kevin

“…Nanoparticle-sensitized photoporation is an upcoming approach for the intracellular delivery of biologics, combining high efficiency and throughput with…”
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Single cell epigenetic visualization assay by Kint, Sam, Van Criekinge, Wim, Vandekerckhove, Linos, De Vos, Winnok H, Bomsztyk, Karol, Krause, Diane S, Denisenko, Oleg

“…Abstract Characterization of the epigenetic status of individual cells remains a challenge. Current sequencing approaches have limited coverage, and it is…”
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Comprehensive polar metabolomics and lipidomics profiling discriminates the transformed from the non-transformed state in colon tissue and cell lines by Rombouts, Caroline, De Spiegeleer, Margot, Van Meulebroek, Lieven, Vanhaecke, Lynn, De Vos, Winnok H.

“…Colorectal cancer (CRC) is the fourth most lethal disease worldwide. Despite an urgent need for therapeutic advance, selective target identification in a…”
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MYCN-induced nucleolar stress drives an early senescence-like transcriptional program in hTERT-immortalized RPE cells by Zanotti, Sofia, Vanhauwaert, Suzanne, Van Neste, Christophe, Olexiouk, Volodimir, Van Laere, Jolien, Verschuuren, Marlies, Van der Meulen, Joni, Mus, Liselot M., Durinck, Kaat, Tilleman, Laurentijn, Deforce, Dieter, Van Nieuwerburgh, Filip, Hogarty, Michael D., Decaesteker, Bieke, De Vos, Winnok H., Speleman, Frank

“…MYCN is an oncogenic driver in neural crest-derived neuroblastoma and medulloblastoma. To better understand the early effects of MYCN activation in a…”
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The cellular response to plasma membrane disruption for nanomaterial delivery by Houthaeve, Gaëlle, De Smedt, Stefaan C., Braeckmans, Kevin, De Vos, Winnok H.

“…Delivery of nanomaterials into cells is of interest for fundamental cell biological research as well as for therapeutic and diagnostic purposes. One way of…”
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Biopolymer-Based Structuring of Liquid Oil into Soft Solids and Oleogels Using Water-Continuous Emulsions as Templates by Patel, Ashok R, Rajarethinem, Pravin S, Cludts, Nick, Lewille, Benny, De Vos, Winnok H, Lesaffer, Ans, Dewettinck, Koen

“…Physical trapping of a hydrophobic liquid oil in a matrix of water-soluble biopolymers was achieved using a facile two-step process by first formulating a…”
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Non-viral delivery of RNA for therapeutic T cell engineering by Berdecka, Dominika, De Smedt, Stefaan C., De Vos, Winnok H., Braeckmans, Kevin

“…[Display omitted] Adoptive T cell transfer has shown great success in treating blood cancers, resulting in a growing number of FDA-approved therapies using…”
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Preparation and rheological characterization of shellac oleogels and oleogel-based emulsions by Patel, Ashok R., Schatteman, Domien, De Vos, Winnok H., Lesaffer, Ans, Dewettinck, Koen

“…Converting liquid oil into oleogel using shellac as a new oleogelator. [Display omitted] •Shellac gels oil at concentration as low as 2wt%.•These oleogels…”
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The Auxin-Regulated CrRLK1L Kinase ERULUS Controls Cell Wall Composition during Root Hair Tip Growth by Schoenaers, Sébastjen, Balcerowicz, Daria, Breen, Gordon, Hill, Kristine, Zdanio, Malgorzata, Mouille, Grégory, Holman, Tara J., Oh, Jaesung, Wilson, Michael H., Nikonorova, Natalia, Vu, Lam Dai, De Smet, Ive, Swarup, Ranjan, De Vos, Winnok H., Pintelon, Isabel, Adriaensen, Dirk, Grierson, Claire, Bennett, Malcolm J., Vissenberg, Kris

“…Root hairs facilitate a plant’s ability to acquire soil anchorage and nutrients. Root hair growth is regulated by the plant hormone auxin and dependent on…”
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Cellular senescence in neuroblastoma by Zanotti, Sofia, Decaesteker, Bieke, Vanhauwaert, Suzanne, De Wilde, Bram, De Vos, Winnok H., Speleman, Frank

“…Neuroblastoma is a tumour that arises from the sympathoadrenal lineage occurring predominantly in children younger than five years. About half of the patients…”
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Auranofin reveals therapeutic anticancer potential by triggering distinct molecular cell death mechanisms and innate immunity in mutant p53 non-small cell lung cancer by Freire Boullosa, Laurie, Van Loenhout, Jinthe, Flieswasser, Tal, De Waele, Jorrit, Hermans, Christophe, Lambrechts, Hilde, Cuypers, Bart, Laukens, Kris, Bartholomeus, Esther, Siozopoulou, Vasiliki, De Vos, Winnok H., Peeters, Marc, Smits, Evelien L.J., Deben, Christophe

“…Auranofin (AF) is an FDA-approved antirheumatic drug with anticancer properties that acts as a thioredoxin reductase 1 (TrxR) inhibitor. The exact mechanisms…”
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Vapor nanobubble is the more reliable photothermal mechanism for inducing endosomal escape of siRNA without disturbing cell homeostasis by Fraire, Juan C., Houthaeve, Gaëlle, Liu, Jing, Raes, Laurens, Vermeulen, Lotte, Stremersch, Stephan, Brans, Toon, García-Díaz Barriga, Gerardo, De Keulenaer, Sarah, Van Nieuwerburgh, Filip, De Rycke, Riet, Vandesompele, Jo, Mestdagh, Pieter, Raemdonck, Koen, De Vos, Winnok H., De Smedt, Stefaan, Braeckmans, Kevin

“…Strategies for controlled delivery of therapeutic siRNA into living cells are in high demand as endosomal escape remains the most prominent bottleneck at the…”
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Delivery of macromolecules in unstimulated T cells by photoporation with polydopamine nanoparticles by Berdecka, Dominika, Harizaj, Aranit, Goemaere, Ilia, Punj, Deep, Goetgeluk, Glenn, De Munter, Stijn, De Keersmaecker, Herlinde, Boterberg, Veerle, Dubruel, Peter, Vandekerckhove, Bart, De Smedt, Stefaan C., De Vos, Winnok H., Braeckmans, Kevin

“…Ex vivo modification of T cells with exogenous cargo is a common prerequisite for the development of T cell therapies, such as chimeric antigen receptor…”
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High-throughput fabrication of vascularized spheroids for bioprinting by De Moor, Lise, Merovci, Idriz, Baetens, Sarah, Verstraeten, Julien, Kowalska, Paulina, Krysko, Dmitri V, De Vos, Winnok H, Declercq, Heidi

“…Overcoming the problem of vascularization remains the main challenge in the field of tissue engineering. As three-dimensional (3D) bioprinting is the rising…”
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Sustained synchronized neuronal network activity in a human astrocyte co-culture system by Kuijlaars, Jacobine, Oyelami, Tutu, Diels, Annick, Rohrbacher, Jutta, Versweyveld, Sofie, Meneghello, Giulia, Tuefferd, Marianne, Verstraelen, Peter, Detrez, Jan R., Verschuuren, Marlies, De Vos, Winnok H., Meert, Theo, Peeters, Pieter J., Cik, Miroslav, Nuydens, Rony, Brône, Bert, Verheyen, An

“…Impaired neuronal network function is a hallmark of neurodevelopmental and neurodegenerative disorders such as autism, schizophrenia, and Alzheimer’s disease…”
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Chemogenetic silencing of neurons in the mouse anterior cingulate area modulates neuronal activity and functional connectivity by Peeters, Lore M., Hinz, Rukun, Detrez, Jan R., Missault, Stephan, De Vos, Winnok H., Verhoye, Marleen, Van der Linden, Annemie, Keliris, Georgios A.

“…The anterior cingulate area (ACC) is an integral part of the prefrontal cortex in mice and supports cognitive functions, including attentional processes,…”
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S100A8‐enriched microglia populate the brain of tau‐seeded and accelerated aging mice by Gruel, Roxane, Bijnens, Baukje, Van Den Daele, Johanna, Thys, Sofie, Willems, Roland, Wuyts, Dirk, Van Dam, Debby, Verstraelen, Peter, Verboven, Rosanne, Roels, Jana, Vandamme, Niels, Mancuso, Renzo, Pita‐Almenar, Juan Diego, De Vos, Winnok H.

“…Long considered to fluctuate between pro‐ and anti‐inflammatory states, it has now become evident that microglia occupy a variegated phenotypic landscape with…”
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Transcriptional analysis through RNA sequencing of giant cells induced by Meloidogyne graminicola in rice roots by Ji, Hongli, Gheysen, Godelieve, Denil, Simon, Lindsey, Keith, Topping, Jennifer F., Nahar, Kamrun, Haegeman, Annelies, De Vos, Winnok H., Trooskens, Geert, Van Criekinge, Wim, De Meyer, Tim, Kyndt, Tina

“…One of the reasons for the progressive yield decline observed in aerobic rice production is the rapid build-up of populations of the rice root knot nematode…”
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Response Surface Methodology to Efficiently Optimize Intracellular Delivery by Photoporation by Goemaere, Ilia, Punj, Deep, Harizaj, Aranit, Woolston, Jessica, Thys, Sofie, Sterck, Karen, De Smedt, Stefaan C, De Vos, Winnok H, Braeckmans, Kevin

“…Photoporation is an up-and-coming technology for the gentle and efficient transfection of cells. Inherent to the application of photoporation is the…”
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Regional vulnerability and spreading of hyperphosphorylated tau in seeded mouse brain by Detrez, Jan R., Maurin, Hervé, Van Kolen, Kristof, Willems, Roland, Colombelli, Julien, Lechat, Benoit, Roucourt, Bart, Van Leuven, Fred, Baatout, Sarah, Larsen, Peter, Nuydens, Rony, Timmermans, Jean-Pierre, De Vos, Winnok H.

“…We have exploited whole brain microscopy to map the progressive deposition of hyperphosphorylated tau in intact, cleared mouse brain. We found that the…”
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