Search Results - "Winitz, S"
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Phosphorylation and activation of a high molecular weight form of phospholipase A2 by p42 microtubule-associated protein 2 kinase and protein kinase C
Published in The Journal of biological chemistry (25-01-1993)“…Phospholipase A2 (PLA2) is the enzyme regulating the release of arachidonic acid in most cell types. A high molecular mass, 85-kDa soluble form of PLA2 (cPLA2)…”
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Involvement of Ras and Raf in the Gi-coupled acetylcholine muscarinic m2 receptor activation of mitogen-activated protein (MAP) kinase kinase and MAP kinase
Published in The Journal of biological chemistry (15-09-1993)“…Stimulation of the acetylcholine muscarinic m2 receptor (m2R) expressed in Rat 1a fibroblasts results in the activation of the cytoplasmic mitogen-activated…”
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Mapping of sites on the Src family protein tyrosine kinases p55blk, p59fyn, and p56lyn which interact with the effector molecules phospholipase C-gamma 2, microtubule-associated protein kinase, GTPase-activating protein, and phosphatidylinositol 3-kinase
Published in Molecular and Cellular Biology (01-09-1993)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Acetylcholine muscarinic m1 receptor regulation of cyclic AMP synthesis controls growth factor stimulation of Raf activity
Published in Molecular and Cellular Biology (01-04-1994)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Epitope-tagged Gq alpha subunits: expression of GTPase-deficient alpha subunits persistently stimulates phosphatidylinositol-specific phospholipase C but not mitogen-activated protein kinase activity regulated by the M1 muscarinic acetylcholine receptor
Published in Proceedings of the National Academy of Sciences - PNAS (01-05-1993)“…Gq is the heterotrimeric guanine nucleotide-binding protein that activates the beta isoforms of phosphatidyl-inositol-specific phospholipase C (PI-PLC). The Gq…”
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Hormonal regulation of MAP kinase in cultured rat inner medullary collecting tubule cells
Published in The American journal of physiology (01-09-1994)“…Mitogen-activated protein (MAP) kinase is a widely expressed protein serine/threonine kinase that serves as a convergence point for many signaling pathways…”
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Myristoylation of the G alpha i2 polypeptide, a G protein alpha subunit, is required for its signaling and transformation functions
Published in Proceedings of the National Academy of Sciences - PNAS (15-10-1992)“…GTPase-inhibiting mutations of the alpha subunit (alpha i2) of the G protein, Gi2, result in constitutive activation of alpha i2 signal transduction functions…”
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Analysis of guanine nucleotides associated with protooncogene ras
Published in Methods in enzymology (1994)Get more information
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Expression of a mutant Gi2 alpha subunit inhibits ATP and thrombin stimulation of cytoplasmic phospholipase A2-mediated arachidonic acid release independent of Ca2+ and mitogen-activated protein kinase regulation
Published in The Journal of biological chemistry (21-01-1994)“…The 85-kDa cytoplasmic phospholipase A2 (cPLA2) is the major hormone and growth factor-regulated enzyme that catalyzes release of arachidonic acid in mammalian…”
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Construction of mutant and chimeric G-protein alpha subunits
Published in Methods in enzymology (1994)Get more information
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Mechanism-based inactivation of thromboxane A2 synthase
Published in Advances in prostaglandin, thromboxane, and leukotriene research (1991)Get more information
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The Regulation of Growth and Intracellular Signaling by Integrins
Published in Endocrine reviews (01-06-1996)“…I. Introduction INTEGRINS are a family of more than 20 different transmembrane receptors composed of noncovalently associated α- and β-subunit heterodimers…”
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How does the G protein, Gi2, transduce mitogenic signals?
Published in Journal of cellular biochemistry (01-04-1994)“…Serpentine receptors coupled to the heterotrimeric G protein, Gi2, are capable of stimulating DNA synthesis in a variety of cell types. A common feature of the…”
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Epitope-tagged G sub(q) alpha subunits: Expression of GTPase-deficient alpha subunits persistently stimulates phosphatidylinositol-specific phospholipase C but not mitogen-activated protein kinase activity regulated by the M sub(1) muscarinic acetylcholine receptor
Published in Proceedings of the National Academy of Sciences - PNAS (01-01-1993)“…G sub(q) is the heterotrimeric guanine nucleotide-binding protein that activates the beta isoforms of phosphatidylinositol-specific phospholipase C (PI-PLC)…”
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Myristoylation of the G alpha sub(i2) polypeptide, a G protein alpha subunit, is required for its signalling and transformation functions
Published in Proceedings of the National Academy of Sciences - PNAS (01-01-1992)“…GTPase-inhibiting mutations of the alpha subunit ( alpha sub(i2)) of the G protein, G sub(i2), result in constitutive activation of alpha sub(i2) signal…”
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Phosphorylation and activation of a high molecular weight form of phospholipase A sub(2) by p42 microtubule-associated protein 2 kinase and protein kinase C
Published in The Journal of biological chemistry (01-01-1993)“…Phospholipase A sub(2) (PLA sub(2)) is the enzyme regulating the release of arachidonic acid in most cell types. A high molecular mass, 85-kDa soluble form of…”
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Mapping of sites on the Src family protein tyrosine kinases p55blk, p59fyn, and p56lyn which interact with the effector molecules phospholipase C-γ2, microtubule-associated protein kinase, GTPase-activating protein, and phophatidylinositol 3-kinase
Published in Molecular and cellular biology (1993)Get full text
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Mapping of sites on the Src family protein tyrosine kinases p55 super(blk), p59 super(fyn), and p56 super(lyn) which interact with the effector molecules phospholipase C- gamma 2, microtubule-associated protein kinase, GTPase-activating protein, and phosphatidylinositol 3-kinase
Published in Molecular and cellular biology (01-01-1993)“…Engagement of the B-cell antigen receptor complex induces immediate activation of receptor-associated Src family tyrosine kinases including p55 super(blk), p59…”
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