Search Results - "Wingrove, James"
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Can face recognition be selectively preserved in some cases of amnesia? A cautionary tale
Published in Cortex (01-04-2024)“…Evidence suggests that some patients with isolated hippocampal damage appear to present with selective preservation of unfamiliar face recognition relative to…”
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A whole blood gene expression-based signature for smoking status
Published in BMC medical genomics (03-12-2012)“…Smoking is the leading cause of preventable death worldwide and has been shown to increase the risk of multiple diseases including coronary artery disease…”
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Development of a blood-based gene expression algorithm for assessment of obstructive coronary artery disease in non-diabetic patients
Published in BMC medical genomics (28-03-2011)“…Alterations in gene expression in peripheral blood cells have been shown to be sensitive to the presence and extent of coronary artery disease (CAD). A…”
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Lack of Association Between Adrenergic Receptor Genotypes and Survival in Heart Failure Patients Treated With Carvedilol or Metoprolol
Published in Journal of the American College of Cardiology (19-08-2008)“…Lack of Association Between Adrenergic Receptor Genotypes and Survival in Heart Failure Patients Treated With Carvedilol or Metoprolol Amy J. Sehnert, Susan E…”
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Multicenter Validation of the Diagnostic Accuracy of a Blood-Based Gene Expression Test for Assessing Obstructive Coronary Artery Disease in Nondiabetic Patients
Published in Annals of internal medicine (05-10-2010)“…Diagnosing obstructive coronary artery disease (CAD) in at-risk patients can be challenging and typically requires both noninvasive imaging methods and…”
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Coronary Atherosclerotic Plaque Detected by Computed Tomographic Angiography in Subjects with Diabetes Compared to Those without Diabetes
Published in PloS one (23-11-2015)“…Little data are available regarding coronary plaque composition and semi-quantitative scores in individuals with diabetes; the extent to which diabetes may…”
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Correlation of Peripheral-Blood Gene Expression With the Extent of Coronary Artery Stenosis
Published in Circulation. Cardiovascular genetics (01-10-2008)“…Correlation of Peripheral-Blood Gene Expression With the Extent of Coronary Artery Stenosis James A. Wingrove, PhD ; Susan E. Daniels, PhD ; Amy J. Sehnert, MD…”
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Rheumatoid arthritis complicates noninvasive whole blood gene expression testing for coronary artery disease
Published in The American heart journal (01-10-2017)“…Our objective was to evaluate an age- and sex-specific gene expression score (ASGES) previously validated to detect obstructive coronary artery disease (CAD)…”
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Developing Peripheral Blood Gene Expression-Based Diagnostic Tests for Coronary Artery Disease: a Review
Published in Journal of cardiovascular translational research (01-08-2015)“…The past 20 years has witnessed the development of technologies designed to measure changes in the expressed human genome, including the levels of RNA…”
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Peripheral blood gene expression signatures which reflect smoking and aspirin exposure are associated with cardiovascular events
Published in BMC medical genomics (12-01-2018)“…Cardiovascular disease and its sequelae are major causes of global mortality, and better methods are needed to identify patients at risk for future…”
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A peripheral blood gene expression score is associated with atherosclerotic Plaque Burden and Stenosis by cardiovascular CT-angiography: results from the PREDICT and COMPASS studies
Published in Atherosclerosis (01-03-2014)“…We previously validated a gene expression score (GES) based on age, sex and peripheral blood cell expression levels of 23 genes measured by quantitative…”
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Identification of factors contributing to variability in a blood-based gene expression test
Published in PloS one (03-07-2012)“…Corus CAD is a clinically validated test based on age, sex, and expression levels of 23 genes in whole blood that provides a score (1-40 points) proportional…”
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An age- and sex-specific gene expression score is associated with revascularization and coronary artery disease: Insights from the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial
Published in The American heart journal (01-02-2017)“…Identifying predictors of coronary artery disease (CAD)-related procedures and events remains a priority. We measured an age- and sex-specific gene expression…”
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Evaluation of a solid matrix for collection and ambient storage of RNA from whole blood
Published in BMC clinical pathology (13-05-2014)“…Whole blood gene expression-based molecular diagnostic tests are becoming increasingly available. Conventional tube-based methods for obtaining RNA from whole…”
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A peripheral blood gene expression score is associated with atherosclerotic Plaque Burden and Stenosis by cardiovascular CT-angiography
Published in Atherosclerosis (01-03-2014)“…Abstract Objective We previously validated a gene expression score (GES) based on age, sex and peripheral blood cell expression levels of 23 genes measured by…”
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Nitric Oxide Contributes to Behavioral, Cellular, and Developmental Responses to Low Oxygen in Drosophila
Published in Cell (09-07-1999)“…A nitric oxide (NO)/cyclic GMP (cGMP) signaling pathway is thought to play an important role in mammalian vasodilation during hypoxia. We show that Drosophila…”
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Identification of an Asymmetrically Localized Sensor Histidine Kinase Responsible for Temporally and Spatially Regulated Transcription
Published in Science (American Association for the Advancement of Science) (25-10-1996)“…Caulobacter crescentus undergoes asymmetric cell division, resulting in a stalked cell and a motile swarmer cell. The genes encoding external components of the…”
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