Search Results - "Winger, A"

The Role of LIN28- let-7 -ARID3B Pathway in Placental Development by Ali, Asghar, Bouma, Gerrit J, Anthony, Russell V, Winger, Quinton A

“…Placental disorders are a major cause of pregnancy loss in humans, and 40-60% of embryos are lost between fertilization and birth. Successful embryo…”
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MicroRNA-mRNA Networks in Pregnancy Complications: A Comprehensive Downstream Analysis of Potential Biomarkers by Ali, Asghar, Hadlich, Frieder, Abbas, Muhammad W, Iqbal, Muhammad A, Tesfaye, Dawit, Bouma, Gerrit J, Winger, Quinton A, Ponsuksili, Siriluck

“…Pregnancy complications are a major cause of fetal and maternal morbidity and mortality in humans. The majority of pregnancy complications initiate due to…”
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LIN28‐let‐7 axis regulates genes in immortalized human trophoblast cells by targeting the ARID3B‐complex by Ali, Asghar, Anthony, Russell V., Bouma, Gerrit J., Winger, Quinton A.

“…Abnormal placental development is one of the main etiological factors for intrauterine growth restriction (IUGR). Here, we show that LIN28A and LIN28B are…”
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Cell-secreted vesicles containing microRNAs as regulators of gamete maturation by da Silveira, Juliano C, de Ávila, Ana Clara F C M, Garrett, Hannah L, Bruemmer, Jason E, Winger, Quinton A, Bouma, Gerrit J

“…Mammalian gamete maturation requires extensive signaling between germ cells and their surrounding somatic cells. In the ovary, theca cells, mural granulosa…”
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Fetal Hypoglycemia Induced by Placental SLC2A3 -RNA Interference Alters Fetal Pancreas Development and Transcriptome at Mid-Gestation by Kennedy, Victoria C, Lynch, Cameron S, Tanner, Amelia R, Winger, Quinton A, Gad, Ahmed, Rozance, Paul J, Anthony, Russell V

“…Glucose, the primary energy substrate for fetal oxidative processes and growth, is transferred from maternal to fetal circulation down a concentration gradient…”
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Impact of Placental SLC2A3 Deficiency during the First-Half of Gestation by Lynch, Cameron S, Kennedy, Victoria C, Tanner, Amelia R, Ali, Asghar, Winger, Quinton A, Rozance, Paul J, Anthony, Russell V

“…In the ruminant placenta, glucose uptake and transfer are mediated by facilitative glucose transporters SLC2A1 (GLUT1) and SLC2A3 (GLUT3). SLC2A1 is located on…”
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Regulation of ACVR1 and ID2 by cell-secreted exosomes during follicle maturation in the mare by da Silveira, Juliano C, Carnevale, Elaine M, Winger, Quinton A, Bouma, Gerrit J

“…Ovarian follicle growth and maturation requires extensive communication between follicular somatic cells and oocytes. Recently, intercellular cell…”
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Shifting perspectives from "oncogenic" to oncofetal proteins; how these factors drive placental development by West, Rachel C, Bouma, Gerrit J, Winger, Quinton A

“…Early human placental development strongly resembles carcinogenesis in otherwise healthy tissues. The progenitor cells of the placenta, the cytotrophoblast,…”
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Assessment of tumor hypoxia in spontaneous canine tumors after treatment with OMX, a novel H-NOX oxygen carrier, with [ 18 F]FMISO PET/CT by Choen, Sangkyung, Kent, Michael S, Loucks, F Alexandra, Winger, Jonathan A, Zwingenberger, Allison L

“…Hypoxia is a detrimental factor in solid tumors, leading to aggressiveness and therapy resistance. OMX, a tunable oxygen carrier from the heme nitric…”
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CSH RNA Interference Reduces Global Nutrient Uptake and Umbilical Blood Flow Resulting in Intrauterine Growth Restriction by Tanner, Amelia R, Lynch, Cameron S, Kennedy, Victoria C, Ali, Asghar, Winger, Quinton A, Rozance, Paul J, Anthony, Russell V

“…Deficiency of the placental hormone chorionic somatomammotropin (CSH) can lead to the development of intrauterine growth restriction (IUGR). To gain insight…”
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HMGA2 is regulated by LIN28 and BRCA1 in human placental cells by West, R. C, McWhorter, E. S, Ali, A, Goetzman, L. N, Russ, J. E, Gonzalez-Berrios, C. L, Anthony, R. V, Bouma, G. J, Winger, Q. A

“…The chromatin associated transcription factor HMGA2 is a downstream target of let-7 miRNAs and binds to chromatin to regulate gene expression. Inhibition of…”
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A Novel Technique of Extracting UCN Decay Lifetime from Storage Chamber Measurements Dominated by Scattering Losses by Mohanmurthy, Prajwal, Formaggio, Joseph, Salvat, Daniel J., Winger, Jeff A.

“…The neutron’s lifetime is a critical parameter in the standard model. Its measurements, particularly measurements using both beamline and ultracold neutron…”
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A Search for Neutron to Mirror Neutron Oscillation Using Neutron Electric Dipole Moment Measurements by Mohanmurthy, Prajwal, Young, Albert R., Winger, Jeff A., Zsigmond, Geza

“…Baryon number violation is a key ingredient of baryogenesis. It has been hypothesized that there could also be a parity-conjugated copy of the standard model…”
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Trophectoderm-Specific Knockdown of LIN28 Decreases Expression of Genes Necessary for Cell Proliferation and Reduces Elongation of Sheep Conceptus by Ali, Asghar, Stenglein, Mark D, Spencer, Thomas E, Bouma, Gerrit J, Anthony, Russell V, Winger, Quinton A

“…LIN28 inhibits miRNA maturation which prevents cell differentiation and promotes proliferation. We hypothesized that the LIN28- axis regulates…”
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Proteomic Characterization of the Nucleolar Linker Histone H1 Interaction Network by Szerlong, Heather J., Herman, Jacob A., Krause, Christine M., DeLuca, Jennifer G., Skoultchi, Arthur, Winger, Quinton A., Prenni, Jessica E., Hansen, Jeffrey C.

“…To investigate the relationship between linker histone H1 and protein–protein interactions in the nucleolus, we used biochemical and proteomics approaches to…”
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Secretome analysis of the thermophilic xylanase hyper-producer Thermomyces lanuginosus SSBP cultivated on corn cobs by Winger, A. M, Heazlewood, J. L, Chan, L. J. G, Petzold, C. J, Permaul, K, Singh, S

“…Thermomyces lanuginosus is a thermophilic fungus known for its ability to produce industrially important enzymes including large amounts of xylanase, the key…”
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Preservation of myocardial contractility during acute hypoxia with OMX-CV, a novel oxygen delivery biotherapeutic by Boehme, Jason, Le Moan, Natacha, Kameny, Rebecca J, Loucks, Alexandra, Johengen, Michael J, Lesneski, Amy L, Gong, Wenhui, Goudy, Brian D., Davis, Tina, Tanaka, Kevin, Davis, Andrew, He, Youping, Long-Boyle, Janel, Ivaturi, Vijay, Gobburu, Jogarao V S, Winger, Jonathan A, Cary, Stephen P, Datar, Sanjeev A, Fineman, Jeffrey R, Krtolica, Ana, Maltepe, Emin

“…The heart exhibits the highest basal oxygen (O2) consumption per tissue mass of any organ in the body and is uniquely dependent on aerobic metabolism to…”
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Impact of Chorionic Somatomammotropin In Vivo RNA Interference Phenotype on Uteroplacental Expression of the IGF Axis by Hord, Taylor K, Tanner, Amelia R, Kennedy, Victoria C, Lynch, Cameron S, Winger, Quinton A, Rozance, Paul J, Anthony, Russell V

“…While fetal growth is dependent on many factors, optimal placental function is a prerequisite for a normal pregnancy outcome. The majority of fetal…”
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Dry skin and skin barrier in early infancy by Rehbinder, E.M., Winger, A.J., Landrø, L., Asarnoj, A., Berents, T.L., Carlsen, K.H., Hedlin, G., Jonassen, C.M., Nordlund, B., Sandvik, L., Skjerven, H.O., Söderhäll, C., Vettukattil, R., Carlsen, K.C.L.

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Identification of microRNAs in exosomes isolated from serum and umbilical cord blood, as well as placentomes of gestational day 90 pregnant sheep by Cleys, Ellane R., Halleran, Jennifer L., McWhorter, Erin, Hergenreder, Joanna, Enriquez, Vanessa A., da Silveira, Juliano C., Bruemmer, Jason E., Winger, Quinton A., Bouma, Gerrit J.

“…SUMMARY Despite reports that circulating levels of maternal serum exosomes increase during pregnancy and that placenta‐specific microRNAs (miRNAs) have been…”
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