Search Results - "Wing, Kristof"

Single-cell eQTL mapping identifies cell type-specific genetic control of autoimmune disease by Yazar, Seyhan, Alquicira-Hernandez, Jose, Wing, Kristof, Senabouth, Anne, Gordon, M Grace, Andersen, Stacey, Lu, Qinyi, Rowson, Antonia, Taylor, Thomas R P, Clarke, Linda, Maccora, Katia, Chen, Christine, Cook, Anthony L, Ye, Chun Jimmie, Fairfax, Kirsten A, Hewitt, Alex W, Powell, Joseph E

“…The human immune system displays substantial variation between individuals, leading to differences in susceptibility to autoimmune disease. We present…”
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Comparison of CRISPR/Cas Endonucleases for in vivo Retinal Gene Editing by Li, Fan, Wing, Kristof, Wang, Jiang-Hui, Luu, Chi D., Bender, James A., Chen, Jinying, Wang, Qi, Lu, Qinyi, Nguyen Tran, Minh Thuan, Young, Kaylene M., Wong, Raymond C. B., Pébay, Alice, Cook, Anthony L., Hung, Sandy S. C., Liu, Guei-Sheung, Hewitt, Alex W.

“…CRISPR/Cas has opened the prospect of direct gene correction therapy for some inherited retinal diseases. Previous work has demonstrated the utility of…”
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Deep Learning-Based Identification of Intraocular Pressure-Associated Genes Influencing Trabecular Meshwork Cell Morphology by Greatbatch, Connor J., Lu, Qinyi, Hung, Sandy, Tran, Son N., Wing, Kristof, Liang, Helena, Han, Xikun, Zhou, Tiger, Siggs, Owen M., Mackey, David A., Liu, Guei-Sheung, Cook, Anthony L., Powell, Joseph E., Craig, Jamie E., MacGregor, Stuart, Hewitt, Alex W.

“…Genome-wide association studies have recently uncovered many loci associated with variation in intraocular pressure (IOP). Artificial intelligence (AI) can be…”
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Building a national eye-care service in post-conflict Timor-Leste by Wing, Kristof, Low, Gwyn, Sharma, Manoj, De Jesus, Frenky, Jeronimo, Belmerio, Verma, Nitin

“…Violent conflict left Timor-Leste with a dismantled health-care workforce and infrastructure after 2001. The absence of existing health and tertiary education…”
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Discovery of a monoclonal, high‐affinity CD8+ T‐cell clone following natural hepatitis C virus infection by Cai, Curtis, Keoshkerian, Elizabeth, Wing, Kristof, Samir, Jerome, Effenberger, Manuel, Schober, Kilian, Bull, Rowena A, Lloyd, Andrew R, Busch, Dirk H, Luciani, Fabio

“…CD8+ T cells recognizing their cognate antigen are typically recruited as a polyclonal population consisting of multiple clonotypes with varying T‐cell…”
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High throughput functional profiling of genes at intraocular pressure loci reveals distinct networks for glaucoma by Greatbatch, Connor J, Lu, Qinyi, Hung, Sandy, Barnett, Alexander J, Wing, Kristof, Liang, Helena, Han, Xikun, Zhou, Tiger, Siggs, Owen M, Mackey, David A, Cook, Anthony L, Senabouth, Anne, Liu, Guei-Sheung, Craig, Jamie E, MacGregor, Stuart, Powell, Joseph E, Hewitt, Alex W

“…Primary open angle glaucoma (POAG) is a leading cause of blindness globally. Characterized by progressive retinal ganglion cell degeneration, the precise…”
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Use of CRISPR/Cas ribonucleoproteins for high throughput gene editing of induced pluripotent stem cells by Wang, Qi, Chear, Sueanne, Wing, Kristof, Stellon, David, Nguyen Tran, Minh Thuan, Talbot, Jana, Pébay, Alice, Hewitt, Alex W, Cook, Anthony L

“…•Optimized protocol for nucleofection of Cas9 ribonucleoproteins into human iPSCs.•Alternative strategies for generation of clonal iPSC lines following gene…”
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The molecular characteristics of non‐small cell lung cancer in the Northern Territory's Top End by Downton, Teesha Dzu Fun, Wing, Kristof, Cosentino, Stevie Brooke, Karanth, Narayan V

“…Aim Indigenous Australians with lung cancer have poorer survival than non‐Indigenous Australians. The reasons for the disparity are not fully understood and…”
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Utility of Self-Destructing CRISPR/Cas Constructs for Targeted Gene Editing in the Retina by Li, Fan, Hung, Sandy S C, Mohd Khalid, Mohd Khairul Nizam, Wang, Jiang-Hui, Chrysostomou, Vicki, Wong, Vickie H Y, Singh, Vikrant, Wing, Kristof, Tu, Leilei, Bender, James A, Pébay, Alice, King, Anna E, Cook, Anthony L, Wong, Raymond C B, Bui, Bang V, Hewitt, Alex W, Liu, Guei-Sheung

“…Safe delivery of CRISPR/Cas endonucleases remains one of the major barriers to the widespread application of genome editing. We previously reported the utility…”
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Comparative performance of the BGI and Illumina sequencing technology for single-cell RNA-sequencing by Senabouth, Anne, Andersen, Stacey, Shi, Qianyu, Shi, Lei, Jiang, Feng, Zhang, Wenwei, Wing, Kristof, Daniszewski, Maciej, Lukowski, Samuel W, Hung, Sandy S C, Nguyen, Quan, Fink, Lynn, Beckhouse, Anthony, Pébay, Alice, Hewitt, Alex W, Powell, Joseph E

“…Abstract The libraries generated by high-throughput single cell RNA-sequencing (scRNA-seq) platforms such as the Chromium from 10× Genomics require…”
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