Search Results - "Wing, John P."

Drosophila Morgue is an F box/ubiquitin conjugase domain protein important for grim-reaper mediated apoptosis by Nambu, John R, Wing, John P, Schreader, Barbara A, Yokokura, Takakazu, Wang, Yiqin, Andrews, Paul S, Huseinovic, Neda, Dong, Carolyn K, Ogdahl, Justyne L, Schwartz, Lawrence M, White, Kristin

“…In Drosophila melanogaster, apoptosis is controlled by the integrated actions of the Grim-Reaper (Grim-Rpr) and Drosophila Inhibitor of Apoptosis (DIAP)…”
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Distinct cell killing properties of the Drosophila reaper, head involution defective, and grim genes by Wing, J P, Zhou, L, Schwartz, L M, Nambu, J R

“…The Drosophila reaper, head involution defective (hid), and grim genes play key roles in regulating the activation of programmed cell death. Two useful systems…”
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cul-1 Is Required for Cell Cycle Exit in C. elegans and Identifies a Novel Gene Family by Kipreos, Edward T, Lander, Lois E, Wing, John P, He, Wei Wu, Hedgecock, Edward M

“…The gene cul-1 (formerly lin-19) is a negative regulator of the cell cycle in C. elegans. Null mutations cause hyperplasia of all tissues. cul-1 is required…”
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Drosophila sickle Is a Novel grim-reaper Cell Death Activator by Wing, John P., Karres, Janina S., Ogdahl, Justyne L., Zhou, Lei, Schwartz, Lawrence M., Nambu, John R.

“…The Drosophila genes reaper, head involution defective (hid), and grim all reside at 75C on chromosome three and encode related proteins that have crucial…”
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ICE-LAP3, a Novel Mammalian Homologue of the Caenorhabditis elegans Cell Death Protein Ced-3 Is Activated during Fas- and Tumor Necrosis Factor-induced Apoptosis (∗) by Duan, Hangjun, Chinnaiyan, Arul M., Hudson, Peter L., Wing, John P., He, Wei-Wu, Dixit, Vishva M.

“…Members of the ICE/ced-3 gene family have been implicated as components of the cell death pathway. Based on similarities with the structural prototype…”
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The RHG motifs of Drosophila Reaper and Grim are important for their distinct cell death-inducing abilities by Wing, J P, Schwartz, L M, Nambu, J R

“…Reaper, Hid, and Grim are three Drosophila cell death activators that each contain a conserved NH(2)-terminal Reaper, Hid, Grim (RHG) motif. We have analyzed…”
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