Search Results - "Winer, Ira S"

Miniaturized phased-array ultrasound and photoacoustic endoscopic imaging system by Basij, Maryam, Yan, Yan, Alshahrani, Suhail S., Helmi, Hamid, Burton, Timothy K., Burmeister, Jay W., Dominello, Michael M., Winer, Ira S., Mehrmohammadi, Mohammad

“…Visualization and detection of early-stage gynecological malignancies represents a challenge for imaging due to limiting factors including tissue…”
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ONC201 induces the unfolded protein response (UPR) in high‐ and low‐grade ovarian carcinoma cell lines and leads to cell death regardless of platinum sensitivity by Rumman, Marufa, Buck, Steven, Polin, Lisa, Dzinic, Sijana, Boerner, Julie, Winer, Ira S.

“…Objectives Treatment of both platinum resistant high grade (HG) and low‐grade (LG) ovarian cancer (OVCA) poses significant challenges as neither respond well…”
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Management of squamous cell vulvar cancer: A review by Deppe, Gunter, Mert, Ismail, Winer, Ira S.

“…Squamous cell vulvar cancer is a rare gynecologic malignancy. Standard treatment for early stage disease consists of wide radical excision of the primary tumor…”
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Merkel cell carcinoma in a patient with noninvasive vulvar Paget's disease by Winer, Ira S., MD, PhD, Lonardo, Fulvio, MD, Johnson, Samuel C., MD, Deppe, Gunter, MD

“…We present the first case of inguinal Merkel cell carcinoma of unknown primary origin in a patient with vulvar Paget's disease. Correlation with immune…”
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Berzosertib plus gemcitabine versus gemcitabine alone in platinum-resistant high-grade serous ovarian cancer: a multicentre, open-label, randomised, phase 2 trial by Konstantinopoulos, Panagiotis A, Cheng, Su-Chun, Wahner Hendrickson, Andrea E, Penson, Richard T, Schumer, Susan T, Doyle, L Austin, Lee, Elizabeth K, Kohn, Elise C, Duska, Linda R, Crispens, Marta A, Olawaiye, Alexander B, Winer, Ira S, Barroilhet, Lisa M, Fu, Siqing, McHale, Michael T, Schilder, Russell J, Färkkilä, Anniina, Chowdhury, Dipanjan, Curtis, Jennifer, Quinn, Roxanne S, Bowes, Brittany, D'Andrea, Alan D, Shapiro, Geoffrey I, Matulonis, Ursula A

“…High-grade serous ovarian cancers show increased replication stress, rendering cells vulnerable to ATR inhibition because of near universal loss of the G1/S…”
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Immune checkpoint expression, microsatellite instability, and mutational burden: Identifying immune biomarker phenotypes in uterine cancer by Jones, Nathaniel L., Xiu, Joanne, Rocconi, Rodney P., Herzog, Thomas J., Winer, Ira S.

“…Increasing grade of endometrioid endometrial cancer (EEC) is associated with aggressive behavior and poor prognosis. The traditional classification system is…”
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A Phase III Study of Pafolacianine Injection (OTL38) for Intraoperative Imaging of Folate Receptor-Positive Ovarian Cancer (Study 006) by Tanyi, Janos L, Randall, Leslie M, Chambers, Setsuko K, Butler, Kristina A, Winer, Ira S, Langstraat, Carrie L, Han, Ernest S, Vahrmeijer, Alexander L, Chon, Hye Sook, Morgan, Mark A, Powell, Matthew A, Tseng, Jill H, Lopez, Alexis S, Wenham, Robert M

“…The adjunctive use of intraoperative molecular imaging (IMI) is gaining acceptance as a potential means to improve outcomes for surgical resection of…”
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Molecular profiles of endometrial cancer tumors among Black patients by Wilhite, Annelise M., Baca, Yasmine, Xiu, Joanne, Paladugu, Rajesh, ElNaggar, Adam C., Brown, Jubilee, Winer, Ira S., Morris, Robert, Erickson, Britt K., Olawaiye, Alexander B., Powell, Matthew, Korn, W. Michael, Rocconi, Rodney P., Khabele, Dineo, Jones, Nathaniel L.

“…Disparate outcomes exist between Black and White patients with endometrial cancer (EC). One contributing factor is the disproportionately low representation of…”
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HER2 in Uterine Serous Carcinoma: Testing platforms and implications for targeted therapy by Klc, Tenley R., Wu, Sharon, Wilhite, Annelise M., Jones, Nathaniel L., Powell, Matthew A., Olawaiye, Alex, Girda, Eugenia, Brown, Jubilee, Puechl, Allison, Ali-Fehmi, Rouba, Winer, Ira S., Herzog, Thomas J., Korn, W. Michael, Erickson, Britt K.

“…HER2 is an important prognostic and therapeutic target in uterine serous carcinoma (USC). Optimal HER2 testing platforms have not been defined and guidelines…”
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Hysteroscopic Morcellation in Endometrial Cancer Diagnosis: Increased Risk? by Kelly, Rebeca A., Contos, George T., Walker, Christopher A., Ayoola-Adeola, Martins, Kim, Seongho, Winer, Ira S.

“…Operative hysteroscopy requires elevated intrauterine pressures, which could lead to the spread of malignant cells into the peritoneal cavity. Currently, there…”
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Health Disparities among Patients with Cancer Who Received Molecular Testing for Biomarker-Directed Therapy by Heath, Elisabeth, Dyson, Gregory, Ribeiro, Jennifer R, Xiu, Joanne, Poorman, Kelsey, Mamdani, Hirva, Al-Hallak, Mohammed N, Shields, Anthony F, Elayoubi, Jailan A, Winer, Ira S, Cackowski, Frank C, Puckrein, Gary A, Lopes, Gilberto de Lima, Jones, Nathaniel, Hauke, Ralph J, Kareff, Samuel A, Radovich, Milan, Sledge, George W, Spetzler, David B, Vidal, Gregory A, Marshall, John L

“…Health disparities present a barrier to successful oncology treatment. The potential for precision oncology to reduce health disparities has not previously…”
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Lysine Residues Lys-19 and Lys-49 of β-Catenin Regulate Its Levels and Function in T Cell Factor Transcriptional Activation and Neoplastic Transformation by Winer, Ira S., Bommer, Guido T., Gonik, Nathan, Fearon, Eric R.

“…Wnt signaling regulates cell fate determination, proliferation, and survival, among other processes. Certain Wnt ligands stabilize the β-catenin protein,…”
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Chemotherapy of vulvar cancer: a review by Deppe, Gunter, Mert, Ismail, Belotte, Jimmy, Winer, Ira S.

“…Summary Squamous cell carcinoma of the vulva is a rare disease with good prognosis if diagnosed early. The standard primary therapy is surgery. Neoadjuvant…”
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Clinical and Pathologic Characteristics of Serous Carcinoma Confined to the Endometrium: A Multi-institutional Study by Semaan, Assaad, Mert, Ismail, Munkarah, Adnan R, Bandyopadhyay, Sudeshna, Mahdi, Haider S, Winer, Ira S, Nucci, Marisa R, Hussein, Yaser, Quershi, Faisal, Hayek, Kinda, Tabassum, Farah, Alosh, Baraa, Schultz, Daniel S, Cote, Michele L, Vijver, Koen K. Van de, Morris, Robert T, Oliva, Esther, Ali-Fehmi, Rouba

“…The objective of this study was to analyze the clinical and pathologic factors in patients with uterine serous carcinoma confined to the endometrium. A total…”
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A Phase III Study of Pafolacianine Injection (OTL38) for Intraoperative Imaging of Folate Receptor–Positive Ovarian Cancer (Study 006) by Tanyi, Janos L., Randall, Leslie M., Chambers, Setsuko K., Butler, Kristina A., Winer, Ira S., Langstraat, Carrie L., Han, Ernest S., Vahrmeijer, Alexander L., Chon, Hye Sook, Morgan, Mark A., Powell, Matthew A., Tseng, Jill H., Lopez, Alexis S., Wenham, Robert M.

“…(Abstracted from J Clin Oncol 2022;41:276–284 Complete resection of macroscopic disease remains a key focus of cytoreductive surgery for the treatment of…”
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Lysine Residues Lys-19 and Lys-49 of β-Catenin Regulate Its Levels and Function in T Cell Factor Transcriptional Activation and Neoplastic Transformation by Ira S. Winer, Guido T. Bommer, Nathan Gonik, Eric R. Fearon

“…Wnt signaling regulates cell fate determination, proliferation, and survival, among other processes. Certain Wnt ligands stabilize the β-catenin protein,…”
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