Search Results - "Wine, Robert N"

Intra- and inter-molecular regulation by intrinsically-disordered regions governs PUF protein RNA binding by Qiu, Chen, Zhang, Zihan, Wine, Robert N., Campbell, Zachary T., Zhang, Jun, Hall, Traci M. Tanaka

“…PUF proteins are characterized by globular RNA-binding domains. They also interact with partner proteins that modulate their RNA-binding activities…”
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divergent Pumilio repeat protein family for pre-rRNA processing and mRNA localization by Qiu, Chen, McCann, Kathleen L., Wine, Robert N., Baserga, Susan J., Hall, Traci M. Tanaka

“…Pumilio/feminization of XX and XO animals (fem)-3 mRNA-binding factor (PUF) proteins bind sequence specifically to mRNA targets using a single-stranded…”
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A crystal structure of a collaborative RNA regulatory complex reveals mechanisms to refine target specificity by Qiu, Chen, Bhat, Vandita D, Rajeev, Sanjana, Zhang, Chi, Lasley, Alexa E, Wine, Robert N, Campbell, Zachary T, Hall, Traci M Tanaka

“…In the germline, Binding Factor (FBF) partners with LST-1 to maintain stem cells. A crystal structure of an FBF-2/LST-1/RNA complex revealed that FBF-2…”
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Tumor necrosis factor p55 and p75 receptors are involved in chemical-induced apoptosis of dentate granule neurons by Harry, G. Jean, Lefebvre d'Hellencourt, Christian, McPherson, Christopher A, Funk, Jason A, Aoyama, Mineyoshi, Wine, Robert N

“…Localized tumor necrosis factor-α (TNFα) elevation has diverse effects in brain injury often attributed to signaling via TNFp55 or TNFp75 receptors. Both…”
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IGF-1 and pAKT Signaling Promote Hippocampal CA1 Neuronal Survival Following Injury to Dentate Granule Cells by Wine, Robert N., McPherson, Christopher A., Harry, G. Jean

“…Insulin-like growth factor-1 (IGF-1) protects neurons from apoptosis and in vivo offers neuroprotective support to hippocampal CA1 pyramidal neurons following…”
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Bipartite interaction sites differentially modulate RNA-binding affinity of a protein complex essential for germline stem cell self-renewal by Qiu, Chen, Wine, Robert N, Campbell, Zachary T, Hall, Traci M Tanaka

“…Abstract In C. elegans, PUF proteins promote germline stem cell self-renewal. Their functions hinge on partnerships with two proteins that are redundantly…”
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Nop9 recognizes structured and single-stranded RNA elements of preribosomal RNA by Zhang, Jun, Teramoto, Takamasa, Qiu, Chen, Wine, Robert N, Gonzalez, Lauren E, Baserga, Susan J, Tanaka Hall, Traci M

“…Nop9 is an essential factor in the processing of preribosomal RNA. Its absence in yeast is lethal, and defects in the human ortholog are associated with breast…”
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Protein Kinase Activity Is Central to Rat Germ Cell Apoptosis Induced by Methoxyacetic Acid by Jindo, Toshimasa, Wine, Robert N., Li, Ling-Hong, Chapin, Robert E.

“…Methoxyacetic acid (MAA) is a major metabolite of ethylene glycol monomethyl ether (EGME). Previous investigations of the testicular lesion induced by EGME…”
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Rat brain arachidonic acid metabolism is increased by a 6‐day intracerebral ventricular infusion of bacterial lipopolysaccharide by Rosenberger, Thad A., Villacreses, Nelly E., Hovda, Jonathan T., Bosetti, Francesca, Weerasinghe, Gayani, Wine, Robert N., Harry, G. Jean, Rapoport, Stanley I.

“…In a rat model of acute neuroinflammation, produced by a 6‐day intracerebral ventricular infusion of bacterial lipopolysaccharide (LPS), we measured brain…”
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p38 mitogen-activated protein kinase interacts with vinculin at focal adhesions during fatty acid-stimulated cell adhesion by George, Margaret D, Wine, Robert N, Lackford, Brad, Kissling, Grace E, Akiyama, Steven K, Olden, Kenneth, Roberts, John D

“…Arachidonic acid stimulates cell adhesion by activating α2β1 integrins in a process that depends on protein kinases, including p38 mitogen activated protein…”
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Alterations in cyclin A, B, and D1 in mouse dentate gyrus following TMT-induced hippocampal damage by McPherson, Christopher A, Kubik, Julie, Wine, Robert N, D'Hellencourt, Christian Lefebvre, Harry, G Jean

“…The interactions of glia and neurons during injury and subsequent neurodegeneration are a subject of interest both in disease and chemical-induced brain…”
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Reproductive Toxicity of Di-n-Butylphthalate in a Continuous Breeding Protocol in Sprague-Dawley Rats by Wine, Robert N., Li, Ling-Hong, Barnes, Leta Hommel, Gulati, Dushyant K., Chapin, Robert E.

“…The phthalate ester di-n-butylphthalate (DBP) is used extensively in the manufacture of plastics; its reproductive toxicity was tested in rats by the National…”
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Inhibition of the enzymatic activity of prostate-specific antigen by boric acid and 3-nitrophenyl boronic acid by Gallardo-Williams, Maria T., Maronpot, Robert R., Wine, Robert N., Brunssen, Susan H., Chapin, Robert E.

“…BACKGROUND Prostate specific antigen (PSA) is a well‐established marker of prostate cancer, but it can also degrade extracellular matrix proteins such as…”
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Identification of Components of Protein Complexes Using a Fluorescent Photo-Cross-Linker and Mass Spectrometry by Wine, Robert N, Dial, John M, Tomer, Kenneth B, Borchers, Christoph H

“…This study describes a novel method for improving the specific recognition, detection, and identification of proteins involved in multiprotein complexes. The…”
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Trimethyltin-induced neurogenesis in the murine hippocampus by Harry, G. Jean, McPherson, Christopher A., Wine, Robert N., Atkinson, Kelly, d'Hellencourt, Christian Lefebvre

“…Neurogenesis continues to occur in the mature rodent brain with one of the most prominent sources for new neurons being the subgranular layer (SGL) of the…”
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Trimethyltin-induced neurogenesis in the murine hippocampus by Harry, G Jean, McPherson, Christopher A, Wine, Robert N, Atkinson, Kelly, Lefebvre d'Hellencourt, Christian

“…Neurogenesis continues to occur in the mature rodent brain with one of the most prominent sources for new neurons being the subgranular layer (SGL) of the…”
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Structure and Control of a Cell‐Cell Adhesion Complex Associated With Spermiation in Rat Seminiferous Epithelium by CHAPIN, ROBERT E., WINE, ROBERT N., HARRIS, MARTHA W., BORCHERS, CRISTOPH H., HASEMAN, JOSEPH K.

“…Spermiation, the release of late spermatids from the Sertoli cell, is disrupted by a number of toxicants. Control of the spermiation process, and the proteins…”
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Rat Testicular Src: Normal Distribution and Involvement in Ethylene Glycol Monomethyl Ether-Induced Apoptosis by Wang, Wei, Wine, Robert N., Chapin, Robert E.

“…Kinase activities were previously proposed to be central to germ cell apoptosis induced by ethylene glycol monomethyl ether (EGME) and its active metabolite…”
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THU559 3D Immuno-smFISH Reveals ER-responsive Cells At The Single-cell Level In ER+ Breast Cancer by Kammel, Laura G, Wine, Robert N, Rodriguez, Joseph

“…Disclosure: L.G. Kammel: None. R.N. Wine: None. J. Rodriguez: None. Abstract: The current guidelines by the American Society of Clinical Oncology/College of…”
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Nop9 recognizes structured and single-stranded RNA elements of preribosomal RNA by Zhang, Jun, Teramoto, Takamasa, Qiu, Chen, Wine, Robert N., Gonzalez, Lauren E., Baserga, Susan J., Hall, Traci M. Tanaka

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