Search Results - "Windle, JJ"

Paget disease of bone by Roodman, G. David, Windle, Jolene J.

“…Paget disease of bone (PD) is characterized by excessive bone resorption in focal areas followed by abundant new bone formation, with eventual replacement of…”
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Paget disease of bone by Roodman, G David, Windle, Jolene J

“…Paget disease of bone (PD) is characterized by excessive bone resorption in focal areas followed by abundant new bone formation, with eventual replacement of…”
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Ras Protein Farnesyltransferase: A Strategic Target for Anticancer Therapeutic Development by ROWINSKY, E. K, WINDLE, J. J, VON HOFF, D. D

“…Ras proteins are guanine nucleotide-binding proteins that play pivotal roles in the control of normal and transformed cell growth and are among the most…”
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Expression of Measles Virus Nucleocapsid Protein in Osteoclasts Induces Paget's Disease‐Like Bone Lesions in Mice by Kurihara, Noriyoshi, Zhou, Hua, Reddy, Sakamuri V, Palacios, Veronica Garcia, Subler, Mark A, Dempster, David W, Windle, Jolene J, Roodman, G David

“…We targeted the MVNP gene to the OCL lineage in transgenic mice. These mice developed abnormal OCLs and bone lesions similar to those found in Paget's…”
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Establishment of an Osteocyte‐like Cell Line, MLO‐Y4 by Kato, Yoichi, Windle, Jolene J., Koop, Barbara A., Mundy, Gregory R., Bonewald, Lynda F.

“…Although osteocytes are the most abundant cells in bone, their functional role remains unclear. In part, this is due to lack of availability of osteocyte cell…”
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Immortalization of pituitary cells at discrete stages of development by directed oncogenesis in transgenic mice by Alarid, E T, Windle, J J, Whyte, D B, Mellon, P L

“…Targeted expression of oncogenes in transgenic mice can immortalize specific cell types to serve as valuable cultured model systems. Utilizing promoter regions…”
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Employing a Transgenic Animal Model to Obtain Cementoblasts In Vitro by D'Errico, John A., Berry, Janice E., Ouyang, Hongjiao, Strayhorn, Christopher L., Windle, Jolene J., Somerman, Martha J.

“…Background: Proper formation of cementum, a mineralized tissue lining the tooth root surface, is required for development of a functional periodontal ligament…”
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Differential effects of p21(WAF1/CIP1) deficiency on MMTV-ras and MMTV-myc mammary tumor properties by Bearss, David J, Lee, Richard J, Troyer, Dean A, Pestell, Richard G, Windle, Jolene J

“…p21(WAF1/CIP1) (p21) functions as a cyclin-dependent kinase (CDK) inhibitor and is a key mediator of p53-dependent growth arrest. However, its role in cell…”
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Reciprocal regulation of neu tyrosine kinase activity and caveolin-1 protein expression in vitro and in vivo. Implications for human breast cancer by Engelman, J A, Lee, R J, Karnezis, A, Bearss, D J, Webster, M, Siegel, P, Muller, W J, Windle, J J, Pestell, R G, Lisanti, M P

“…Neu (c-erbB2) is a proto-oncogene product that encodes an epidermal growth factor-like receptor tyrosine kinase. Amplification of wild-type c-Neu and…”
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Rubber particles from four different species, examined by transmission electron microscopy and electron-paramagnetic-resonance spin labeling, are found to consist of a homogeneous rubber core enclosed by a contiguous, monolayer biomembrane by Cornish, K, Wood, D.F, Windle, J.J

“…The physical characteristics of rubber particles from the four rubber (cis-1,4-polyisoprene) producing species Euphorbia lactiflua Phil., Ficus elastica Roxb.,…”
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Combretastatin A-4 Prodrug in the Treatment of a Murine Model of Retinoblastoma by Escalona-Benz, Erika, Jockovich, Maria-Elena, Murray, Timothy G, Hayden, Brandy, Hernandez, Eleut, Feuer, William, Windle, Jolene J

“…To evaluate the effect of subconjunctival injections of combretastatin A-4 phosphate (CA-4P) prodrug treatment on tumor vasculature and growth in an animal…”
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Osteoclasts formed by measles virus-infected osteoclast precursors from hCD46 transgenic mice express characteristics of pagetic osteoclasts by Reddy, S V, Kurihara, N, Menaa, C, Landucci, G, Forthal, D, Koop, B A, Windle, J J, Roodman, G D

“…Pagetic osteoclasts (OCLs) are abnormal in size and contain paramyxoviral-like nuclear inclusions that cross-react with antibodies to measles virus (MV)…”
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Immortalization of hypothalamic GnRH neurons by genetically targeted tumorigenesis by Mellon, P L, Windle, J J, Goldsmith, P C, Padula, C A, Roberts, J L, Weiner, R I

“…By genetically targeting tumorigenesis to specific hypothalamic neurons in transgenic mice using the promoter region of the gonadotropin-releasing hormone…”
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Apoptosis or retinoblastoma : alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53 by HOWES, K. A, RANSOM, N, PAPERMASTER, D. S, LASUDRY, J. G. H, ALBERT, D. M, WINDLE, J. J

“…A transgenic mouse model for retinoblastoma was produced previously by directing SV40 T antigen expression to retinal photoreceptor cells using the promoter of…”
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Cyclin kinase inhibitor p21 potentiates bile acid–induced apoptosis in hepatocytes that is dependent on p53 by Qiao, Liang, McKinstry, Robert, Gupta, Seema, Gilfor, Donna, Windle, Jolene J., Hylemon, Philip B., Grant, Steven, Fisher, Paul B., Dent, Paul

“…Prolonged activation of the mitogen-activated protein kinase (MAPK) pathway enhances expression of the cyclin kinase inhibitor p21 that can promote growth…”
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A Farnesyltransferase Inhibitor Induces Tumor Regression in Transgenic Mice Harboring Multiple Oncogenic Mutations by Mediating Alterations in Both Cell Cycle Control and Apoptosis by Barrington, Rebecca E., Subler, Mark A., Rands, Elaine, Omer, Charles A., Miller, Patricia J., Hundley, Jeffrey E., Koester, Steven K., Troyer, Dean A., Bearss, David J., Conner, Michael W., Gibbs, Jackson B., Hamilton, Kelly, Koblan, Kenneth S., Mosser, Scott D., O'Neill, Timothy J., Schaber, Michael D., Senderak, Edith T., Windle, Jolene J., Oliff, Allen, Kohl, Nancy E.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cell lines of the pituitary gonadotrope lineage derived by targeted oncogenesis in transgenic mice by Windle, J J, Weiner, R I, Mellon, P L

“…Study of the molecular and cellular biology of the gonadotropin hormones would be greatly facilitated by the availability of immortalized anterior pituitary…”
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Genetic determinants of response to chemotherapy in transgenic mouse mammary and salivary tumors by Bearss, D J, Subler, M A, Hundley, J E, Troyer, D A, Salinas, R A, Windle, J J

“…Several transgenic mouse tumor models were utilized to explore how specific genetic alterations affect the tumor cell response to chemotherapeutic agents in…”
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Immortalized murine osteoblasts derived from BMP 2-T-antigen expressing transgenic mice by Ghosh-Choudhury, N, Windle, J J, Koop, B A, Harris, M A, Guerrero, D L, Wozney, J M, Mundy, G R, Harris, S E

“…Osteoblast cell lines capable of undergoing bone formation in vitro would provide useful models for understanding gene expression during bone cell…”
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Increased tumor proliferation and genomic instability without decreased apoptosis in MMTV-ras mice deficient in p53 by Hundley, Jeff E., Koester, Steven K., Troyer, Dean A., Hilsenbeck, Susan G., Subler, Mark A., Windle, Jolene J.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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