Search Results - "Windham, Ian"
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1
The cell biology of APOE in the brain
Published in Trends in cell biology (01-04-2024)“…Apolipoprotein E (APOE) mediates multiple aspects of brain lipid homeostasis in both physiological and pathological contexts.Evidence points to defects in…”
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2
Lipid droplets go through a (liquid crystalline) phase
Published in The Journal of cell biology (07-11-2022)“…Lipid droplets (LDs) are key organelles for fat storage and trafficking. In this issue, Rogers et al. (2022. J. Cell…”
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3
Helicobacter pylori Biofilm Formation and Its Potential Role in Pathogenesis
Published in Microbiology and molecular biology reviews (01-06-2018)“…Despite decades of effort, infections remain difficult to treat. Over half of the world's population is infected by , which is a major cause of duodenal and…”
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Interplay between Amoxicillin Resistance and Osmotic Stress in Helicobacter pylori
Published in Journal of bacteriology (17-05-2022)“…Rising antibiotic resistance rates are a growing concern for all pathogens, including Helicobacter pylori. We previously examined the association of specific…”
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5
Nuclear Movement in Growing Arabidopsis Root Hairs Involves Both Actin Filaments and Microtubules
Published in Journal of experimental botany (12-09-2022)“…The migration of nuclei during growth and development processes is a conserved phenomenon among man karyotic species. In Arabidopsis thaliana, the movement of…”
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6
In vitro antibacterial activity of nimbolide against Helicobacter pylori
Published in Journal of ethnopharmacology (01-03-2022)“…Nimbolide is one of hundreds of phytochemicals that have been identified within the neem tree (Azadirachta indica A. Juss). As an evergreen tree native to the…”
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7
Helicobacter pylori Biofilm Formation Is Differentially Affected by Common Culture Conditions, and Proteins Play a Central Role in the Biofilm Matrix
Published in Applied and environmental microbiology (15-07-2018)“…The concept of biofilm formation is relatively new. To help provide a foundation for future biofilm studies, we characterized the biofilm formation ability of…”
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APOE traffics to astrocyte lipid droplets and modulates triglyceride saturation and droplet size
Published in The Journal of cell biology (01-04-2024)“…The E4 variant of APOE strongly predisposes individuals to late-onset Alzheimer's disease. We demonstrate that in response to lipogenesis, apolipoprotein E…”
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9
Analysis of fitness costs associated with metronidazole and amoxicillin resistance in Helicobacter pylori
Published in Helicobacter (Cambridge, Mass.) (01-10-2020)“…Background Increasing rates of antibiotic resistance are a major concern for all pathogens, including H. pylori. However, increased resistance often coincides…”
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10
A Circle RNA Regulatory Axis Promotes Lung Squamous Metastasis via CDR1-Mediated Regulation of Golgi Trafficking
Published in Cancer research (Chicago, Ill.) (15-11-2020)“…Lung squamous carcinoma (LUSC) is a highly metastatic disease with a poor prognosis. Using an integrated screening approach, we found that miR-671-5p reduces…”
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11
CidR and CcpA Synergistically Regulate Staphylococcus aureus cidABC Expression
Published in Journal of bacteriology (01-12-2019)“…The death and lysis of a subpopulation of cells during biofilm development benefit the whole bacterial population through the release of an important component…”
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ArsRS-Dependent Regulation of homB Contributes to Helicobacter pylori Biofilm Formation
Published in Frontiers in microbiology (02-08-2018)“…One elusive area in the field is an understanding of why some infections result in gastric cancer, yet others persist asymptomatically for the life-span of the…”
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13
SrrAB Modulates Staphylococcus aureus Cell Death through Regulation of cidABC Transcription
Published in Journal of bacteriology (01-04-2016)“…The death and lysis of a subpopulation in Staphylococcus aureus biofilm cells are thought to benefit the surviving population by releasing extracellular DNA, a…”
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