Search Results - "Windhagen, A."

Physical capacity and quality of life in patients with multiple sclerosis by Kerling, A, Keweloh, K, Tegtbur, U, Kück, M, Grams, L, Horstmann, H, Windhagen, A

“…Physical capacity (PC) and quality of life (QoL) are both reduced in multiple sclerosis (MS). Aim of our study was to investigate limitations in PC and QoL in…”
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Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions by Windhagen, A, Newcombe, J, Dangond, F, Strand, C, Woodroofe, M N, Cuzner, M L, Hafler, D A

“…Resting autoreactive T cells are present in the circulation of normal individuals without pathologic consequences. In autoimmune animal models, stimulation of…”
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Interferon‐β up‐regulates the expression of co‐stimulatory molecules CD80, CD86 and CD40 on monocytes: significance for treatment of multiple sclerosis by MARCKMANN, S., WIESEMANN, E., HILSE, R., TREBST, C., STANGEL, M., WINDHAGEN, A.

“…SUMMARY Interferon (IFN)‐β reduces the biological activity of multiple sclerosis (MS), a presumably T cell‐mediated autoimmune disease of central nervous…”
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Correlation of serum IL‐13 and IL‐5 levels with clinical response to Glatiramer acetate in patients with multiple sclerosis by WIESEMANN, E., KLATT, J., WENZEL, C., HEIDENREICH, F., WINDHAGEN, A.

“…SUMMARY Glatiramer acetate (GA) is effective in the treatment of Multiple Sclerosis (MS) presumably by the induction of an immunoregulatory T‐cell response. We…”
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Paraneoplastic autoimmune encephalitis associated with CV2/CRMP-5 IgG antineuronal antibodies in a patient with thymoma by Werry, C., Götz, F., Wurster, U., Stangel, M., Giess, R., Heidenreich, F., Windhagen, A.

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Altered CD45 isoform expression in C77G carriers influences cytokine responsiveness and adhesion properties of T cells by Windhagen, A, Sönmez, D, Hornig-Do, H.T, Kalinowsky, A, Schwinzer, R

“…The C77G polymorphism in exon A of the human CD45 gene occurs with low frequency in healthy individuals. An enhanced frequency of C77G individuals has been…”
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Expression of chemokine receptors on peripheral blood mononuclear cells of patients with immune-mediated neuropathies treated with intravenous immunoglobulins by Trebst, C., Brunhorn, K., Lindner, M., Windhagen, A., Stangel, M.

“…Intravenous immunoglobulin (IVIg) is an efficacious treatment for immune‐mediated neuropathies like Guillain–Barré syndrome (GBS), chronic inflammatory…”
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Mx proteins in blood leukocytes for monitoring interferon beta-1b therapy in patients with MS by KRACKE, A, VON WUSSOW, P, AL-MASRI, A. N, DALLEY, G, WINDHAGEN, A, HEIDENREICH, F

“…To correlate Mx protein (Mx) levels in lysed blood leukocytes with the clinical response to interferon (IFN) beta-1b (IFNbeta-1b) in relapsing-remitting MS…”
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276 EFFECT OF GLOBUS PALLIDUS INTERNUS (GPI) AND/OR PEDUNCULOPONTINE NUCLEUS (PPN) DBS ON POSTURE AND GAIT IGNITION IN ADVANCED PARKINSON'S DISEASE by Schrader, C, Capelle, H, Dressler, D, Windhagen, A, Krauss, J, Seehaus, F

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Cytokine secretion of myelin basic protein reactive T cells in patients with multiple sclerosis by Windhagen, A., E. Anderson, D., Carrizosa, A., Balashov, K., L. Weiner, H., A. Hafler, D.

“…The objective of this study was to determine whether autoreactive T cells in patients with multiple sclerosis (MS) are polarized and committed in their…”
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Lymphadenopathy in patients with multiple sclerosis undergoing treatment with glatiramer acetate by WINDHAGEN, A, MANIAK, S, MARCKMANN, S, WILKENING, A, LINDERT, R-B, HEIDENREICH, F, BLASCZYK, R

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Variable immortalizing potential and frequent virus latency in blood-derived T-cell clones infected with human T-cell leukemia virus type I by RICHARDSON, J. H, HÖLLSBERG, P, WINDHAGEN, A, CHILD, L. A, HAFLER, D. A, LEVER, A. M. L

“…Human T-cell leukemia virus type I (HTLV-I)-infected T cells expanded in vitro by single-cell cloning provide a unique system for investigating virus-cell…”
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Exostosis of the internal auditory canal in a patient with myotonic dystrophy by Arnoldner, C, Stöver, T, Bartling, S H, Windhagen, A, Durisin, M, Averbeck, T, Lenarz, T

“…A 53-year-old patient with myotonic dystrophy presented to our clinic with progressive bilateral hearing loss. The ENT status and particularly the otological…”
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Human polymorphonuclear neutrophils express a B7-1-like molecule by Windhagen, Anja, Maniak, Susanna, Gebert, Andreas, Ferger, Isabel, Wurster, Ulrich, Heidenreich, Fedor

“…Polymorphonuclear neutrophils (PMN) are part of the innate immune system and are first‐line effector cells in acute inflammatory responses. On activation PMNs…”
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Effects of interferon-β on co-signaling molecules: upregulation of CD40, CD86 and PD-L2 on monocytes in relation to clinical response to interferon-β treatment in patients with multiple sclerosis by Wiesemann, Elke, Deb, Milani, Trebst, Corinna, Hemmer, Bernhard, Stangel, Martin, Windhagen, Anja

“…Interferon-beta (IFN-β) reduces disease activity in a subgroup of patients with relapsing remitting multiple sclerosis (MS). The mechanism of action as well as…”
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The 77C->G Mutation in the Human CD45 (PTPRC) Gene Leads to Increased Intensity of TCR Signaling in T Cell Lines from Healthy Individuals and Patients with Multiple Sclerosis by Do, Hue-Tran, Baars, Wiebke, Borns, Katja, Windhagen, Anja, Schwinzer, Reinhard

“…The 77C-->G mutation in exon A of the human CD45 gene occurs with low frequency in healthy individuals. An enhanced frequency of 77C-->G individuals has been…”
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Early identification of interferon-beta responders by ex vivo testing in patients with multiple sclerosis by Wiesemann, Elke, Deb, Milani, Hemmer, Bernhard, Radeke, Heinfried H, Windhagen, Anja

“…Abstract Interferon-beta (IFN-β) is an effective treatment for a subgroup of patients with multiple sclerosis (MS). The mechanism of action as well as the…”
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Gross muscle pseudohypertrophy in myeloma-associated light chain amyloidosis by WINDHAGEN, Anja, BUFLER, Johannes, NEUDECKER, Stefan

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Modulation of cytokine patterns of human autoreactive T cell clones by a single amino acid substitution of their peptide ligand by Windhagen, Anja, Schooz, Christian, Höllsberg, Per, Fukaura, Hikoaki, Sette, Alessandro, Hafler, David A.

“…We demonstrate that cognate peptide ligands altered at T call receptor (TCR) contact residues and bound to class II major histocompetability complex can change…”
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Interferon-β increases the stimulatory capacity of monocyte-derived dendritic cells to induce IL-13, IL-5 and IL-10 in autologous T-cells by Wiesemann, Elke, Sönmez, Daniela, Heidenreich, Fedor, Windhagen, Anja

“…Dendritic cells (DCs) are key regulators of immune responses and have been associated with autoimmunity in animal models and human disease. The effects of…”
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