Search Results - "Windemuth, Sophia"

Dynamic Gene Expression Mitigates Mutational Escape in Lysis-Driven Bacteria Cancer Therapy by Liguori, Filippo, Pellicciotta, Nicola, Milanetti, Edoardo, Xi Windemuth, Sophia, Ruocco, Giancarlo, Di Leonardo, Roberto, Danino, Tal

“…Engineered bacteria have the potential to deliver therapeutic payloads directly to tumors, with synthetic biology enabling precise control over therapeutic…”
Get full text

Iron-Tannin Coating Reduces Clearance and Increases Tumor Colonization of Systemically Delivered Bacteria by Windemuth, Sophia, Hahn, Jaeseung, You, Jicheng, Wang, Zihan, Ding, Suwan, Tarrab, Stephanie, Coker, Courtney, Leong, Kam W., Danino, Tal

“…Engineered bacteria offer a novel approach to targeted cancer therapy, but challenges remain in delivering enough bacteria safely for effective treatment…”
Get full text

SYST-31 PROBIOTIC DELIVERY TO ORTHOTOPIC GLIOBLASTOMA MULTIFORME MODELS AS AN IMMUNOTHERAPY by Windemuth, Sophia, Ali, Alessandra, Molotkov, Andrei, Hahn, Jaeseung, Danino, Tal, Leong, Kam, Mintz, Akiva

“…Abstract Therapeutic bacteria have been shown to be effective as an immunotherapy in several types of solid tumors because of their inherent immunogenicity and…”
Get full text