Search Results - "Windebank, Anthony J."

Chemotherapy‐induced peripheral neuropathy: A current review by Staff, Nathan P., Grisold, Anna, Grisold, Wolfgang, Windebank, Anthony J.

“…Chemotherapy‐induced peripheral neuropathy (CIPN) is a common dose‐limiting side effect experienced by patients receiving treatment for cancer. Approximately…”
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Incidence and disease burden of chemotherapy-induced peripheral neuropathy in a population-based cohort by Shah, Arya, Hoffman, E Matthew, Mauermann, Michelle L, Loprinzi, Charles L, Windebank, Anthony J, Klein, Christopher J, Staff, Nathan P

“…ObjectiveTo assess disease burden of chemotherapy-induced peripheral neuropathy (CIPN), which is a common dose-limiting side effect of neurotoxic chemotherapy…”
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Chemotherapy-induced neuropathy by Windebank, Anthony J., Grisold, Wolfgang

“…Neurotoxic side effects of cancer therapy are second in frequency to hematological toxicity. Unlike hematological side effects that can be treated with…”
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CELLTOP Clinical Trial: First Report From a Phase 1 Trial of Autologous Adipose Tissue–Derived Mesenchymal Stem Cells in the Treatment of Paralysis Due to Traumatic Spinal Cord Injury by Bydon, Mohamad, Dietz, Allan B., Goncalves, Sandy, Moinuddin, F M, Alvi, Mohammed Ali, Goyal, Anshit, Yolcu, Yagiz, Hunt, Christine L., Garlanger, Kristin L., Del Fabro, Anna S., Reeves, Ronald K., Terzic, Andre, Windebank, Anthony J., Qu, Wenchun

“…Spinal cord injury (SCI) is a devastating condition with limited pharmacological treatment options to restore function. Regenerative approaches have recently…”
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Cisplatin induced Mitochondrial DNA damage in dorsal root ganglion neurons by Podratz, Jewel L, Knight, Andrew M, Ta, Lauren E, Staff, Nathan P, Gass, Jennifer M, Genelin, Konstantin, Schlattau, Alexander, Lathroum, Liselle, Windebank, Anthony J

“…Abstract Cisplatin is a platinum-based chemotherapeutic agent that induces peripheral neuropathy in 30% of patients. Peripheral neuropathy is the dose limiting…”
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A randomized placebo‐controlled phase 3 study of mesenchymal stem cells induced to secrete high levels of neurotrophic factors in amyotrophic lateral sclerosis by Cudkowicz, Merit E., Lindborg, Stacy R., Goyal, Namita A., Miller, Robert G., Burford, Matthew J., Berry, James D., Nicholson, Katharine A., Mozaffar, Tahseen, Katz, Jonathan S., Jenkins, Liberty J., Baloh, Robert H., Lewis, Richard A., Staff, Nathan P., Owegi, Margaret A., Berry, Donald A., Gothelf, Yael, Levy, Yossef S., Aricha, Revital, Kern, Ralph Z., Windebank, Anthony J., Brown, Robert H.

“…Introduction/Aims Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative illness with great unmet patient need. We aimed to evaluate whether…”
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Comprehensive immune profiling reveals substantial immune system alterations in a subset of patients with amyotrophic lateral sclerosis by Gustafson, Michael P, Staff, Nathan P, Bornschlegl, Svetlana, Butler, Greg W, Maas, Mary L, Kazamel, Mohamed, Zubair, Adeel, Gastineau, Dennis A, Windebank, Anthony J, Dietz, Allan B

“…Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with a median lifespan of 2-3 years after diagnosis. There are few meaningful…”
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Intrathecal delivery of adipose-derived mesenchymal stem cells in traumatic spinal cord injury: Phase I trial by Bydon, Mohamad, Qu, Wenchun, Moinuddin, F. M., Hunt, Christine L., Garlanger, Kristin L., Reeves, Ronald K., Windebank, Anthony J., Zhao, Kristin D., Jarrah, Ryan, Trammell, Brandon C., El Sammak, Sally, Michalopoulos, Giorgos D., Katsos, Konstantinos, Graepel, Stephen P., Seidel-Miller, Kimberly L., Beck, Lisa A., Laughlin, Ruple S., Dietz, Allan B.

“…Intrathecal delivery of autologous culture-expanded adipose tissue-derived mesenchymal stem cells (AD-MSC) could be utilized to treat traumatic spinal cord…”
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Controlling dispersion of axonal regeneration using a multichannel collagen nerve conduit by Yao, Li, de Ruiter, Godard C.W, Wang, Huan, Knight, Andrew M, Spinner, Robert J, Yaszemski, Michael J, Windebank, Anthony J, Pandit, Abhay

“…Abstract Single channel conduits are used clinically in nerve repair as an alternative to the autologous nerve graft. Axons regenerating across single channel…”
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Intrathecal administration of autologous mesenchymal stem cells in multiple system atrophy by Singer, Wolfgang, Dietz, Allan B, Zeller, Anita D, Gehrking, Tonette L, Schmelzer, James D, Schmeichel, Ann M, Gehrking, Jade A, Suarez, Mariana D, Sletten, David M, Minota Pacheco, Karla V, Coon, Elizabeth A, Sandroni, Paola, Benarroch, Eduardo E, Fealey, Robert D, Matsumoto, Joseph Y, Bower, James H, Hassan, Anhar, McKeon, Andrew, Windebank, Anthony J, Mandrekar, Jay N, Low, Phillip A

“…OBJECTIVEThis phase I/II study sought to explore intrathecal administration of mesenchymal stem cells (MSCs) as therapeutic approach to multiple system atrophy…”
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Segment-Specific Orientation of the Dorsal and Ventral Roots for Precise Therapeutic Targeting of Human Spinal Cord by Mendez, Alan, Islam, Riazul, Latypov, Timur, Basa, Prathima, Joseph, Ogeneitsega J., Knudsen, Bruce, Siddiqui, Ahad M., Summer, Priska, Staehnke, Luke J., Grahn, Peter J., Lachman, Nirusha, Windebank, Anthony J., Lavrov, Igor A.

“…To provide precise description of the dorsal and ventral roots orientation along with the main spinal cord anatomical measurements and their segment-specific…”
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Comparison and characterization of multiple biomaterial conduits for peripheral nerve repair by Daly, William T, Knight, Andrew M, Wang, Huan, de Boer, Ralph, Giusti, Guilherme, Dadsetan, Mahrokh, Spinner, Robert J, Yaszemski, Michael J, Windebank, Anthony J

“…Abstract Four biomaterial tubes, poly(lactic-co-glycolic acid) (PLGA), poly(caprolactone fumarate) (PCLF), a neutral oligo[(polyethylene glycol) fumarate]…”
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Designing ideal conduits for peripheral nerve repair by de Ruiter, Godard C W, Malessy, Martijn J A, Yaszemski, Michael J, Windebank, Anthony J, Spinner, Robert J

“…Nerve tubes, guides, or conduits are a promising alternative for autologous nerve graft repair. The first biodegradable empty single lumen or hollow nerve…”
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Author Correction: Intrathecal delivery of adipose-derived mesenchymal stem cells in traumatic spinal cord injury: Phase I trial by Bydon, Mohamad, Qu, Wenchun, Moinuddin, F. M., Hunt, Christine L., Garlanger, Kristin L., Reeves, Ronald K., Windebank, Anthony J., Zhao, Kristin D., Jarrah, Ryan, Trammell, Brandon C., El Sammak, Sally, Michalopoulos, Giorgos D., Katsos, Konstantinos, Graepel, Stephen P., Seidel-Miller, Kimberly L., Beck, Lisa A., Laughlin, Ruple S., Dietz, Allan B.

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Bortezomib alters microtubule polymerization and axonal transport in rat dorsal root ganglion neurons by Staff, Nathan P., Podratz, Jewel L., Grassner, Lukas, Bader, Miranda, Paz, Justin, Knight, Andrew M., Loprinzi, Charles L., Trushina, Eugenia, Windebank, Anthony J.

“…•We develop an in vitro model of bortezomib-induced neuropathy using rat dorsal root ganglia.•Bortezomib causes a sensory axonopathy based on whole explant…”
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Transient Receptor Potential Vanilloid 1 is Essential for Cisplatin-Induced Heat Hyperalgesia in Mice by Ta, Lauren E, Bieber, Allan J, Carlton, Susan M, Loprinzi, Charles L, Low, Philip A, Windebank, Anthony J

“…Background: Cisplatin is primarily used for treatment of ovarian and testicular cancer. Oxaliplatin is the only effective treatment for metastatic colorectal…”
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Candidate pathway-based genetic association study of platinum and platinum–taxane related toxicity in a cohort of primary lung cancer patients by Johnson, Cassandra, Pankratz, Vernon S, Velazquez, Ana I, Aakre, Jeremiah A, Loprinzi, Charles L, Staff, Nathan P, Windebank, Anthony J, Yang, Ping

“…Abstract Background Chemotherapy-induced peripheral neuropathy (CIPN) is a common toxicity secondary to chemotherapy. Genetic factors may be important in…”
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Development of Electrically Conductive Oligo(polyethylene glycol) Fumarate-Polypyrrole Hydrogels for Nerve Regeneration by Runge, M. Brett, Dadsetan, Mahrokh, Baltrusaitis, Jonas, Ruesink, Terry, Lu, Lichun, Windebank, Anthony J, Yaszemski, Michael J

“…Electrically conductive hydrogel composites consisting of oligo(polyethylene glycol) fumarate (OPF) and polypyrrole (PPy) were developed for applications in…”
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Open-Spaced Ridged Hydrogel Scaffolds Containing TiO2-Self-Assembled Monolayer of Phosphonates Promote Regeneration and Recovery Following Spinal Cord Injury by Siddiqui, Ahad M., Thiele, Frederic, Stewart, Rachel N., Rangnick, Simone, Weiss, Georgina J., Chen, Bingkun K., Silvernail, Jodi L., Strickland, Tammy, Nesbitt, Jarred J., Lim, Kelly, Schwarzbauer, Jean E., Schwartz, Jeffrey, Yaszemski, Michael J., Windebank, Anthony J., Madigan, Nicolas N.

“…The spinal cord has a poor ability to regenerate after an injury, which may be due to cell loss, cyst formation, inflammation, and scarring. A promising…”
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Material properties and electrical stimulation regimens of polycaprolactone fumarate–polypyrrole scaffolds as potential conductive nerve conduits by Moroder, Philipp, Runge, M. Brett, Wang, Huan, Ruesink, Terry, Lu, Lichun, Spinner, Robert J., Windebank, Anthony J., Yaszemski, Michael J.

“…The mechanical and electrical properties of polycaprolactone fumarate–polypyrrole (PCLF–PPy) scaffolds were studied under physiological conditions to evaluate…”
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