Search Results - "Winch, Chad"

Temozolomide and seizure outcomes in a randomized clinical trial of elderly glioblastoma patients by Climans, Seth A., Brandes, Alba A., Cairncross, J. Gregory, Ding, Keyue, Fay, Michael, Laperriere, Normand, Menten, Johan, Nishikawa, Ryo, O’Callaghan, Christopher J., Perry, James R., Phillips, Claire, Roa, Wilson, Wick, Wolfgang, Winch, Chad, Mason, Warren P.

“…Introduction Tumor-related epilepsy may respond to chemotherapy. In a previously-published multi-centre randomized clinical trial of 562 elderly glioblastoma…”
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The Future Is Now-Prospective Study of Radiosurgery for More Than 4 Brain Metastases to Start in 2018 by Roberge, David, Brown, Paul D, Whitton, Anthony, O'Callaghan, Chris, Leis, Anne, Greenspoon, Jeffrey, Smith, Grace Li, Hu, Jennifer J, Nichol, Alan, Winch, Chad, Chan, Michael D

“…Stereotactic radiosurgery (SRS) has replaced whole brain radiotherapy (WBRT) as standard therapy for most patients with four or fewer brain metastases due to…”
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Short-Course Radiation plus Temozolomide in Elderly Patients with Glioblastoma by Perry, James R, Laperriere, Normand, O’Callaghan, Christopher J, Brandes, Alba A, Menten, Johan, Phillips, Claire, Fay, Michael, Nishikawa, Ryo, Cairncross, J. Gregory, Roa, Wilson, Osoba, David, Rossiter, John P, Sahgal, Arjun, Hirte, Hal, Laigle-Donadey, Florence, Franceschi, Enrico, Chinot, Olivier, Golfinopoulos, Vassilis, Fariselli, Laura, Wick, Antje, Feuvret, Loic, Back, Michael, Tills, Michael, Winch, Chad, Baumert, Brigitta G, Wick, Wolfgang, Ding, Keyue, Mason, Warren P

“…Older patients with glioblastoma appear to benefit more from treatment combining a shorter course (3 weeks rather than 6 weeks) of radiotherapy together with…”
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A randomized trial of ibrutinib and R-GDP prior to stem cell transplant in relapsed diffuse large B-cell lymphoma by Kuruvilla, John, Rushton, Christopher, Villa, Diego, Aslam, Muhammad, Prica, Anca, Abdel Samad, Nizar, Doucet, Stephane, Dudebout, Jill, Fleury, Isabelle, Fraser, Graeme, Larouche, Jean-Francois, Shafey, Mona, Skrabek, Pamela, Skamene, Tanya, Morin, Ryan D, Alcaide, Miguel, Ben-Neriah, Susana, Lee, David, Winch, Chad, Shepherd, Lois E, Scott, David W, Crump, Michael, Chen, Bingshu E, Hay, Annette E

“…In the LY.17 randomized phase II clinical trial, adults with relapsed and refractory diffuse large B-cell lymphoma treated with ibrutinib-R-GDP (IR-GDP) for up…”
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Impact of lymphopenia on survival for elderly patients with glioblastoma: A secondary analysis of the CCTG CE.6 (EORTC 26062-22061, TROG03.01) randomized clinical trial by Song, Andrew Jehyun, Ding, Keyue, Laperriere, Normand, Perry, James R., Mason, Warren P., Winch, Chad, O'Callaghan, Christopher J., Menten, Johan, Brandes, Alba Ariela, Phillips, Claire, Fay, Michael F., Nishikawa, Ryo, Osoba, David, Cairncross, Gregory, Roa, Wilson, Wick, Wolfgang, Shi, Wenyin

“…Abstract only 2547 Background: Lymphopenia (LMP) may lead to worse outcomes for patients with glioblastoma (GBM). This study is a secondary analysis of the…”
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Temozolomide does not meaningfully reduce seizure frequency in elderly glioblastoma patients (614) by Climans, Seth, Brandes, Alba, Cairncross, J. Greg, Ding, Keyue, Fay, Michael, Laperriere, Normand, Menten, Johan, Nishikawa, Ryo, O’Callaghan, Christopher, Osoba, David, Perry, James, Phillips, Claire, Roa, Wilson, Winch, Chad, Mason, Warren

“…Abstract only…”
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A phase I study of romidepsin, gemcitabine, dexamethasone and cisplatin combination therapy in the treatment of peripheral T-cell and diffuse large B-cell lymphoma; the Canadian cancer trials group LY.15 study by Reiman, Tony, Savage, Kerry J., Crump, Michael, Cheung, Matthew C., MacDonald, David, Buckstein, Rena, Couban, Stephen, Piliotis, Eugenia, Imrie, Kevin, Spaner, David, Shivakumar, Sudeep, Kuruvilla, John, Villa, Diego, Shepherd, Lois E., Skamene, Tanya, Winch, Chad, Chen, Bingshu E., Hay, Annette E.

“…We investigated GDP (gemcitabine, 1000 mg/m 2 IV d1, d8; dexamethasone, 40 mg po d1-4; cisplatin, 75 mg/m 2 IV d1) combined with romidepsin on days 1 and 8…”
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A Phase I Study of Romidepsin, Gemcitabine, Dexamethasone and Cisplatin Combination Therapy in the Treatment of Peripheral T-Cell and Diffuse Large B-Cell Lymphoma: Canadian Cancer Trials Group Study LY.15 by Reiman, Tony, Savage, Kerry J., Crump, Michael, Cheung, Matthew, MacDonald, David A., Buckstein, Rena, Couban, Stephen, Piliotis, Eugenia, Imrie, Kevin R, Spaner, David, Shivakumar, Sudeep, Kuruvilla, John, Villa, Diego, Shepherd, Lois E., Skamene, Tanya, Winch, Chad, Chen, Bingshu E, Hay, Annette E

“…Background: The outcome of peripheral T-cell lymphomas (PTCLs) remains poor and improved therapies are needed. Retrospective data suggest that integration of…”
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Impact of lymphopenia on survival for elderly patients with glioblastoma: A secondary analysis of the CCTG CE.6 (EORTC 26062-22061, TROG03.01) randomized clinical trial by Song, Andrew J, Ding, Keyue, Alnahhas, Iyad, Laperriere, Normand J, Perry, James, Mason, Warren P, Winch, Chad, O'Callaghan, Chris J, Menten, Johan J, Brandes, Alba A, Phillips, Claire, Fay, Michael F, Nishikawa, Ryo, Osoba, David, Cairncross, J Gregory, Roa, Wilson, Wick, Wolfgang, Shi, Wenyin

“…Lymphopenia may lead to worse outcomes for glioblastoma patients. This study is a secondary analysis of the CCTG CE.6 trial evaluating the impact of…”
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OV21/PETROC: A randomized Gynecologic Cancer Intergroup (GCIG) phase II study of intraperitoneal (IP) versus intravenous (IV) chemotherapy following neoadjuvant chemotherapy and optimal debulking surgery in epithelial ovarian cancer (EOC) by Mackay, Helen, Gallagher, Christopher J., Parulekar, Wendy R., Ledermann, Jonathan A., Armstrong, Deborah Kay, Gourley, Charlie, Romero, Ignacio, Feeney, Amanda, Bessette, Paul, Hall, Marcia, Weberpals, Johanne Ingrid, Hall, Geoff, Lau, Susie K, Gauthier, Philippe, Fung-Kee-Fung, Michael, Eisenhauer, Elizabeth A., Winch, Chad, Tu, Dongsheng, Provencher, Diane M.

“…Abstract only LBA5503 Background: The aim of this 2 stage randomized trial was to evaluate whether women undergoing neoadjuvant IV chemotherapy followed by…”
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A phase III randomized controlled trial of short-course radiotherapy with or without concomitant and adjuvant temozolomide in elderly patients with glioblastoma (CCTG CE.6, EORTC 26062-22061, TROG 08.02, NCT00482677) by Perry, James R., Laperriere, Normand, O'Callaghan, Christopher J., Brandes, Alba Ariela, Menten, Johan, Phillips, Claire, Fay, Michael F., Nishikawa, Ryo, Cairncross, J. Gregory, Roa, Wilson, Osoba, David, Sahgal, Arjun, Hirte, Hal W., Wick, Wolfgang, Laigle-Donadey, Florence, Franceschi, Enrico, Chinot, Olivier L., Winch, Chad, Ding, Keyue, Mason, Warren P.

“…Abstract only LBA2 Background: The EORTC (26981-22981)/NCIC CTG (CE.3) RCT in newly diagnosed glioblastoma (GB) showed increased overall survival (OS) with…”
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A phase III randomized controlled trial of short-course radiotherapy with or without concomitant and adjuvant temozolomide in elderly patients with glioblastoma (CCTG CE.6, EORTC 26062-22061, TROG 08.02, NCT00482677) by Perry, James R., Laperriere, Normand, O'Callaghan, Christopher J., Brandes, Alba Ariela, Menten, Johan, Phillips, Claire, Fay, Michael F., Nishikawa, Ryo, Cairncross, J. Gregory, Roa, Wilson, Osoba, David, Sahgal, Arjun, Hirte, Hal W., Wick, Wolfgang, Laigle-Donadey, Florence, Franceschi, Enrico, Chinot, Olivier L., Winch, Chad, Ding, Keyue, Mason, Warren P.

“…Abstract only…”
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OV21/PETROC: A randomized Gynecologic Cancer Intergroup (GCIG) phase II study of intraperitoneal (IP) versus intravenous (IV) chemotherapy following neoadjuvant chemotherapy and optimal debulking surgery in epithelial ovarian cancer (EOC) by Mackay, Helen, Gallagher, Christopher J., Parulekar, Wendy R., Ledermann, Jonathan A., Armstrong, Deborah Kay, Gourley, Charlie, Romero, Ignacio, Feeney, Amanda, Bessette, Paul, Hall, Marcia, Weberpals, Johanne Ingrid, Hall, Geoff, Lau, Susie K, Gauthier, Philippe, Fung-Kee-Fung, Michael, Eisenhauer, Elizabeth A., Winch, Chad, Tu, Dongsheng, Provencher, Diane M.

“…Abstract only…”
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Corrigendum to: Impact of lymphopenia on survival for elderly patients with glioblastoma: A secondary analysis of the CCTG CE.6 (EORTC 26062-22061, TROG 08.02) randomized clinical trial by Song, Andrew J, Ding, Keyue, Alnahhas, Iyad, Laperriere, Normand J, Perry, James, Mason, Warren P, Winch, Chad, O’Callaghan, Chris J, Menten, Johan J, Brandes, Alba A, Phillips, Claire, Fay, Michael F, Nishikawa, Ryo, Osoba, David, Cairncross, J Gregory, Roa, Wilson, Wick, Wolfgang, Shi, Wenyin

“…[This corrects the article DOI: 10.1093/noajnl/vdab153.]…”
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An Investigation and Review of Futility Analysis Methods in Phase III Oncology Trials by Winch, Chad

“…The general objective of this thesis was to improve understandings of design, conduct and analysis of randomized controlled trials (RCTs). The specific…”
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A phase III randomized controlled trial of short-course radiotherapy with or without concomitant and adjuvant temozolomide in elderly patients with glioblastoma (NCIC CTG CE.6, EORTC 26062-22061, TROG 08.02, NCT00482677) by Perry, James R., O'Callaghan, Christopher J, Ding, Keyue, Roa, Wilson, Mason, Warren P., Cairncross, J. Gregory, Brandes, Alba Ariela, Menten, Johan, Phillips, Claire, Fay, Michael F., Nishikawa, Ryo, Winch, Chad, Laperriere, Normand

“…Abstract only TPS2104 Background: The EORTC (26981-22981)/NCIC CTG (CE.3) RCT in newly diagnosed GBM found improved survival with concomitant and adjuvant…”
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A PHASE III RANDOMIZED CONTROLLED TRIAL OF SHORT-COURSE RADIOTHERAPY WITH OR WITHOUT CONCOMITANT AND ADJUVANT TEMOZOLOMIDE IN ELDERLY PATIENTS WITH GLIOBLASTOMA (NCIC CTG CE.6, EORTC 26062-22061, TROG 08.02, NCT00482677) by MD, J. R. P., O'Callaghan, C. J., Ding, K., Roa, W., Mason, W. P., Cairncross, J. G., Brandes, A. A., Menten, J., Phillips, C., Fay, M. F., Nishikawa, R., Winch, C., Laperriere, N.

“…BACKGROUND: The EORTC (26981-22981)/NCIC CTG (CE.3) RCT in newly diagnosed GBM showed increased survival with concomitant and adjuvant temozolomide (TMZ) added…”
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