Search Results - "Winborn, Christina S."

Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations by Alami, Nael H, Smith, Rebecca B, Carrasco, Monica A, Williams, Luis A, Winborn, Christina S, Han, Steve S W, Kiskinis, Evangelos, Winborn, Brett, Freibaum, Brian D, Kanagaraj, Anderson, Clare, Alison J, Badders, Nisha M, Bilican, Bilada, Chaum, Edward, Chandran, Siddharthan, Shaw, Christopher E, Eggan, Kevin C, Maniatis, Tom, Taylor, J Paul

“…The RNA-binding protein TDP-43 regulates RNA metabolism at multiple levels, including transcription, RNA splicing, and mRNA stability. TDP-43 is a major…”
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Prominin-1 Is a Novel Regulator of Autophagy in the Human Retinal Pigment Epithelium by Bhattacharya, Sujoy, Yin, Jinggang, Winborn, Christina S, Zhang, Qiuhua, Yue, Junming, Chaum, Edward

“…Prominin-1 (Prom1) is a transmembrane glycoprotein, which is expressed in stem cell lineages, and has recently been implicated in cancer stem cell survival…”
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Polymicrobial sepsis influences NK-cell-mediated immunity by diminishing NK-cell-intrinsic receptor-mediated effector responses to viral ligands or infections by Jensen, Isaac J, Winborn, Christina S, Fosdick, Micaela G, Shao, Peng, Tremblay, Mikaela M, Shan, Qiang, Tripathy, Sandeep Kumar, Snyder, Christopher M, Xue, Hai-Hui, Griffith, Thomas S, Houtman, Jon C, Badovinac, Vladimir P

“…The sepsis-induced cytokine storm leads to severe lymphopenia and reduced effector capacity of remaining/surviving cells. This results in a prolonged state of…”
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Sensitization of Calcitonin Gene-Related Peptide Receptors by Receptor Activity-Modifying Protein-1 in the Trigeminal Ganglion by Zhang, Zhongming, Winborn, Christina S, Marquez de Prado, Blanca, Russo, Andrew F

“…The neuropeptide calcitonin gene-related peptide (CGRP) from the trigeminal ganglion has been established as a key player in the pathogenesis of migraine. In…”
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Genomic regulation of senescence and innate immunity signaling in the retinal pigment epithelium by Chaum, Edward, Winborn, Christina S., Bhattacharya, Sujoy

“…The tumor suppressor p53 is a major regulator of genes important for cell cycle arrest, senescence, apoptosis, and innate immunity, and has recently been…”
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Acute reorganization of postsynaptic GABAA receptors reveals the functional impact of molecular nanoarchitecture at inhibitory synapses by Olah, Samantha S., Kareemo, Dean J., Buchta, William C., Sinnen, Brooke L., Miller, Carley N., Actor-Engel, Hannah S., Gookin, Sara E., Winborn, Christina S., Kleinjan, Mason S., Crosby, Kevin C., Aoto, Jason, Smith, Katharine R., Kennedy, Matthew J.

“…Neurotransmitter receptors partition into nanometer-scale subdomains within the postsynaptic membrane that are precisely aligned with presynaptic…”
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Diverse CD8 T Cell Responses to Viral Infection Revealed by the Collaborative Cross by Martin, Matthew D., Sompallae, Ramakrishna, Winborn, Christina S., Harty, John T., Badovinac, Vladimir P.

“…Enhanced host protection against re-infection requires generation of memory T cells of sufficient quantity and functional quality. Unlike well-studied inbred…”
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zapERtrap: A light-regulated ER release system reveals unexpected neuronal trafficking pathways by Bourke, Ashley M, Schwartz, Samantha L, Bowen, Aaron B, Kleinjan, Mason S, Winborn, Christina S, Kareemo, Dean J, Gutnick, Amos, Schwarz, Thomas L, Kennedy, Matthew J

“…Here we introduce zapalog-mediated endoplasmic reticulum trap (zapERtrap), which allows one to use light to precisely trigger forward trafficking of diverse…”
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Sepsis-Induced State of Immunoparalysis Is Defined by Diminished CD8 T Cell-Mediated Antitumor Immunity by Danahy, Derek B, Kurup, Samarchith P, Winborn, Christina S, Jensen, Isaac J, Harty, John T, Griffith, Thomas S, Badovinac, Vladimir P

“…Patients who survive sepsis experience long-term immunoparalysis characterized by numerical and/or functional lesions in innate and adaptive immunity that…”
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Regulation of cargo exocytosis by a Reps1-Ralbp1-RalA module by Wang, Shifeng, Chen, Xu, Crisman, Lauren, Dou, Ximing, Winborn, Christina S, Wan, Chun, Puscher, Harrison, Yin, Qian, Kennedy, Matthew J, Shen, Jingshi

“…Surface levels of membrane proteins are determined by a dynamic balance between exocytosis-mediated surface delivery and endocytosis-dependent retrieval from…”
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Precision Mapping of Amyloid-β Binding Reveals Perisynaptic Localization and Spatially Restricted Plasticity Deficits by Actor-Engel, Hannah S, Schwartz, Samantha L, Crosby, Kevin C, Sinnen, Brooke L, Prikhodko, Olga, Ramsay, Harrison J, Bourne, Jennifer N, Winborn, Christina S, Lucas, Alexandra, Smith, Katharine R, Dell'Acqua, Mark L, Kennedy, Matthew J

“…Secreted amyloid-β (Aβ) peptide forms neurotoxic oligomeric assemblies thought to cause synaptic deficits associated with Alzheimer's disease (AD). Soluble Aβ…”
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Sepsis-induced state of immunoparalysis is defined by diminished CD8 T cell-mediated anti-tumor immunity1 by Danahy, Derek B, Kurup, Samarchith P, Winborn, Christina S, Jensen, Isaac J, Harty, John T, Griffith, Thomas S, Badovinac, Vladimir P

“…Patients who survive sepsis experience long-term immunoparalysis characterized by numerical and/or functional lesions in innate and adaptive immunity that…”
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Acute reorganization of postsynaptic GABA A receptors reveals the functional impact of molecular nanoarchitecture at inhibitory synapses by Olah, Samantha S, Kareemo, Dean J, Buchta, William C, Sinnen, Brooke L, Miller, Carley N, Actor-Engel, Hannah S, Gookin, Sara E, Winborn, Christina S, Kleinjan, Mason S, Crosby, Kevin C, Aoto, Jason, Smith, Katharine R, Kennedy, Matthew J

“…Neurotransmitter receptors partition into nanometer-scale subdomains within the postsynaptic membrane that are precisely aligned with presynaptic…”
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Axonal transport of TDP-43 mRNA granules in neurons is impaired by ALS-causing mutations by Alami, Nael H., Smith, Rebecca B., Carrasco, Monica A., Williams, Luis A., Winborn, Christina S., Han, Steve S. W., Kiskinis, Evangelos, Winborn, Brett, Freibaum, Brian D., Kanagaraj, Anderson, Clare, Alison J., Badders, Nisha M., Bilican, Bilada, Chaum, Edward, Chandran, Siddharthan, Shaw, Christopher E., Eggan, Kevin C., Maniatis, Tom, Taylor, J. Paul

“…The RNA binding protein TDP-43 regulates RNA metabolism at multiple levels, including transcription, RNA splicing, and mRNA stability. TDP-43 is a major…”
Get full text