Search Results - "Winberg, J. O."
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Medium- and short-chain dehydrogenase/reductase gene and protein families: Structure-function relationships in short-chain alcohol dehydrogenases
Published in Cellular and molecular life sciences : CMLS (01-12-2008)“… The structure-function relationships of alcohol dehydrogenases from the large family of short-chain dehydrogenase/reductase (SDR) enzymes are described. It…”
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Expression of TWEAK/Fn14 in neuroblastoma: Implications in tumorigenesis
Published in International journal of oncology (01-04-2013)“…Tumor necrosis factor-like weak inducer of apoptosis (TWEAK), a member of the tumor necrosis factor (TNF) family of cytokines, acts on responsive cells via…”
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S100A4 involvement in metastasis : Deregulation of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in osteosarcoma cells transfected with an anti-S100A4 ribozyme
Published in Cancer research (Chicago, Ill.) (15-09-1999)“…The biological function of the metastasis-associated gene S100A4 is not fully understood, although there is evidence indicating interactions between the gene…”
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The Role of Liver Alcohol Dehydrogenase Isoenzymes in the Oxidation of Glycolethers in Male and Female Rats
Published in Toxicology and applied pharmacology (01-05-1998)“…The glycolethers 2-methoxyethanol (2-ME), 2-ethoxyethanol (2-EE), and 2-butoxyethanol (2-BE) are used as solvents and have teratogenic, spermatotoxic, and…”
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Characterization and pro‐inflammatory responses of spore and hyphae samples from various mold species
Published in Indoor air (01-01-2018)“…Mold particles from Aspergillus fumigatus, Penicillium chrysogenum, Aspergillus versicolor, and Stachybotrys chartarum have been linked to respiratory‐related…”
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Structure-function relationships in short-chain alcohol dehydrogenases
Published in Cellular and molecular life sciences : CMLS (01-12-2008)Get full text
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Serglycin-binding proteins in activated macrophages and platelets
Published in Journal of leukocyte biology (01-04-1996)“…The major proteoglycan in macrophages and platelets is the chondroitin sulfate proteoglycan serglycin. To study the biological role of serglycin, its binding…”
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Modulation of Disease Severity of Dystrophic Epidermolysis Bullosa By a Splice Site Mutation in Combination with a Missense Mutation in the COL7A1 Gene
Published in Human molecular genetics (01-07-1997)“…Dystrophic epidermolysis bullosa (EBD) is a clinically heterogeneous skin disorder, characterized by abnormal anchoring fibrils (AF) and loss of…”
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Immunohistochemical and Mutation Analyses Demonstrate That Procollagen VII Is Processed to Collagen VII through Removal of the NC-2 Domain
Published in The Journal of cell biology (01-10-1995)“…Collagen VII is the major structural constituent of anchoring fibrils in the skin. It is synthesized as a procollagen that is larger than the collagen…”
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Inhibition of chemerin/CMKLR1 axis in neuroblastoma cells reduces clonogenicity and cell viability in vitro and impairs tumor growth in vivo
Published in Oncotarget (10-11-2017)“…Pro-inflammatory cells, cytokines, and chemokines are essential in promoting a tumor supporting microenvironment. Chemerin is a chemotactic protein and a…”
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Proteases in Plasma and Kidney of db/db Mice as Markers of Diabetes-Induced Nephropathy
Published in ISRN endocrinology (01-01-2011)“…Db/db mice are overweight, dyslipidemic and develop diabetic complications, relevant for similar complications in human type 2 diabetes. We have used db/db and…”
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Interleukin-1 alpha and basic fibroblast growth factor induction of matrix metalloproteinases and their inhibitors in osteosarcoma cells is modulated by the metastasis associated protein CAPL
Published in Anticancer research (01-09-1998)“…Several recent investigations have shown that the expression of the CAPL protein seems to be of importance in the metastatic potential in some types of cancer…”
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Drosophila melanogaster alcohol dehydrogenase: product-inhibition studies
Published in Biochemical journal (01-08-1994)“…The Drosophila melanogaster alleloenzymes Adh(S) and Adh(F) have been studied with respect to product inhibition by using the two substrate couples…”
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Drosophila melanogaster alcohol dehydrogenase: mechanism of aldehyde oxidation and dismutation
Published in Biochemical journal (01-02-1998)“…Drosophila alcohol dehydrogenase (Adh) catalyses the oxidation of both alcohols and aldehydes. In the latter case, the oxidation is followed by a reduction of…”
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An intact eight‐membered water chain in drosophilid alcohol dehydrogenases is essential for optimal enzyme activity
Published in The FEBS journal (01-08-2012)“…All drosophilid alcohol dehydrogenases contain an eight‐member water chain connecting the active site with the solvent at the dimer interface. A similar water…”
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Effect of adenosine analogues on the expression of matrix metalloproteinases and their inhibitors from human dermal fibroblasts
Published in Biochemical pharmacology (15-05-1997)“…The effect of the cytostatic and antiviral adenosine analogues 3-deazaadenosine (c 3Ado) and 3-deaza-(±)-aristeromycin ( c 3 Ari) on human skin fibroblasts was…”
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Junctional epidermolysis bullosa inversa (locus EBR2A) assigned to 1q31 by linkage and association to LAMC1
Published in Human molecular genetics (01-08-1994)“…Junctional epidermolysis bullosa inversa is an autosomal recessive blistering skin disease with an ultrastructural hemidesmosome defect similar to that of the…”
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Macrophages Secrete Matrix Metalloproteinase 9 Covalently Linked to the Core Protein of Chondroitin Sulphate Proteoglycans
Published in Journal of molecular biology (08-12-2000)“…Matrix metalloproteinases (MMPs) secreted from the leukemic macrophage cell-line THP-1 have been investigated. Under serum-free conditions, this cell-line…”
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Anchoring Fibrils, Collagen VII, and Neutral Metalloproteases in Recessive Dystrophic Epidermolysis Bullosa Inversa
Published in Journal of investigative dermatology (01-11-1992)“…Structure of the anchoring fibrils, expression of collagen VII, and gelatinolytic activity in skit fibroblasts were assessed in six patients with epidermolysis…”
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