Search Results - "Wilton, Rosemarie"
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Wireless Optogenetic Modulation of Cortical Neurons Enabled by Radioluminescent Nanoparticles
Published in ACS nano (23-03-2021)“…While offering high-precision control of neural circuits, optogenetics is hampered by the necessity to implant fiber-optic waveguides in order to deliver…”
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Wastewater Surveillance for Poliovirus in Selected Jurisdictions, United States, 2022-2023
Published in Emerging infectious diseases (01-11-2024)“…Wastewater testing can inform public health action as a component of polio outbreak response. During 2022-2023, a total of 7 US jurisdictions (5 states and 2…”
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PeakDecoder enables machine learning-based metabolite annotation and accurate profiling in multidimensional mass spectrometry measurements
Published in Nature communications (28-04-2023)“…Multidimensional measurements using state-of-the-art separations and mass spectrometry provide advantages in untargeted metabolomics analyses for studying…”
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4
Functional Imaging of Microbial Interactions With Tree Roots Using a Microfluidics Setup
Published in Frontiers in plant science (15-04-2020)“…Coupling microfluidics with microscopy has emerged as a powerful approach to study at cellular resolution the dynamics in plant physiology and root-microbe…”
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5
Structure of Surface Layer Homology (SLH) Domains from Bacillus anthracis Surface Array Protein
Published in The Journal of biological chemistry (22-07-2011)“…Surface (S)-layers, para-crystalline arrays of protein, are deposited in the envelope of most bacterial species. These surface organelles are retained in the…”
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6
Fast, Ratiometric FRET from Quantum Dot Conjugated Stabilized Single Chain Variable Fragments for Quantitative Botulinum Neurotoxin Sensing
Published in Nano letters (14-10-2015)“…Botulinum neurotoxin (BoNT) presents a significant hazard under numerous realistic scenarios. The standard detection scheme for this fast-acting toxin is a…”
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7
A New Suite of Plasmid Vectors for Fluorescence-Based Imaging of Root Colonizing Pseudomonads
Published in Frontiers in plant science (01-02-2018)“…In the terrestrial ecosystem, plant-microbe symbiotic associations are ecologically and economically important processes. To better understand these…”
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Evaluation of chromosomal insertion loci in the Pseudomonas putida KT2440 genome for predictable biosystems design
Published in Metabolic engineering communications (01-12-2020)“…The development of Pseudomonas strains for industrial production of fuels and chemicals will require the integration of heterologous genes and pathways into…”
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Comparative analysis of 10 small molecules binding to carbonic anhydrase II by different investigators using Biacore technology
Published in Analytical biochemistry (01-12-2006)“…In this benchmark study, 26 investigators were asked to characterize the kinetics and affinities of 10 sulfonamide inhibitors binding to the enzyme carbonic…”
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10
Analysis of periplasmic sensor domains from Anaeromyxobacter dehalogenans 2CP‐C: Structure of one sensor domain from a histidine kinase and another from a chemotaxis protein
Published in MicrobiologyOpen (Weinheim) (01-10-2013)“…Anaeromyxobacter dehalogenans is a δ‐proteobacterium found in diverse soils and sediments. It is of interest in bioremediation efforts due to its…”
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Expression and purification of recombinant human receptor for advanced glycation endproducts in Escherichia coli
Published in Protein expression and purification (01-05-2006)“…The receptor for advanced glycation endproducts (RAGE) is a multiligand receptor that binds a variety of structurally and functionally unrelated ligands,…”
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12
Interaction of antidiabetic α‐glucosidase inhibitors and gut bacteria α‐glucosidase
Published in Protein science (01-08-2018)“…Carbohydrate hydrolyzing α‐glucosidases are commonly found in microorganisms present in the human intestine microbiome. We have previously reported crystal…”
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13
Silica Nanodepletors: Targeting and Clearing Alzheimer's β‐Amyloid Plaques
Published in Advanced functional materials (01-04-2020)“…Abnormal accumulation of β‐amyloid (Aβ) peptide aggregates in the brain is a major hallmark of Alzheimer's disease (AD). Aβ aggregates interfere with neuronal…”
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Comparison of wild-type KT2440 and genome-reduced EM42 Pseudomonas putida strains for muconate production from aromatic compounds and glucose
Published in Metabolic engineering (23-11-2023)“…Pseudomonas putida KT2440 is a robust, aromatic catabolic bacterium that has been widely engineered to convert bio-based and waste-based feedstocks to target…”
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15
Comparison of wild-type KT2440 and genome-reduced EM42 Pseudomonas putida strains for muconate production from aromatic compounds and glucose
Published in Metabolic engineering (01-01-2024)“…Pseudomonas putida KT2440 is a robust, aromatic catabolic bacterium that has been widely engineered to convert bio-based and waste-based feedstocks to target…”
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16
Novel α-glucosidase from human gut microbiome: substrate specificities and their switch
Published in The FASEB journal (01-10-2010)“…The human intestine harbors a large number of microbes forming a complex microbial community that greatly affects the physiology and pathology of the host. In…”
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17
PeakDecoder enables machine learning-based metabolite annotation and accurate profiling in multidimensional mass spectrometry measurements
Published in Nature communications (28-04-2023)“…Multidimensional measurements using state-of-the-art separations and mass spectrometry provide advantages in untargeted metabolomics analyses for studying…”
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18
Silica Nanodepletors: Silica Nanodepletors: Targeting and Clearing Alzheimer's β‐Amyloid Plaques (Adv. Funct. Mater. 15/2020)
Published in Advanced functional materials (14-04-2020)“…In article number 1910475, Elena A. Rozhkova, Chan Beum Park, Joonseok Lee, and co‐workers design Aβ nanodepletors constructed from ultralarge mesoporous…”
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19
Bacillus anthracis Inosine 5′-Monophosphate Dehydrogenase in Action: The First Bacterial Series of Structures of Phosphate Ion‑, Substrate‑, and Product-Bound Complexes
Published in Biochemistry (Easton) (07-08-2012)“…Inosine 5′-monophosphate dehydrogenase (IMPDH) catalyzes the first unique step of the GMP branch of the purine nucleotide biosynthetic pathway. This enzyme is…”
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Structural analysis of free and liganded forms of the Fab fragment of a high‐affinity anti‐cocaine antibody, h2E2
Published in Acta crystallographica. Section F, Structural biology communications (01-11-2019)“…A high‐affinity anti‐cocaine monoclonal antibody, designated h2E2, is entering phase 1 clinical trials for cocaine abuse therapy. To gain insight into the…”
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