Search Results - "Wilson J Ribot"
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Cluster 1 Type VI Secretion System Is a Major Virulence Determinant in Burkholderia pseudomallei
Published in Infection and Immunity (01-04-2011)“…The Burkholderia pseudomallei K96243 genome encodes six type VI secretion systems (T6SSs), but little is known about the role of these systems in the biology…”
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Type VI secretion is a major virulence determinant in Burkholderia mallei
Published in Molecular microbiology (01-06-2007)“…Burkholderia mallei is a host-adapted pathogen and a category B biothreat agent. Although the B. mallei VirAG two-component regulatory system is required for…”
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The capsule of Bacillus anthracis protects it from the bactericidal activity of human defensins and other cationic antimicrobial peptides
Published in PLoS pathogens (29-09-2022)“…During infection, Bacillus anthracis bacilli encounter potent antimicrobial peptides (AMPs) such as defensins. We examined the role that B . anthracis capsule…”
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The Madagascar hissing cockroach as a novel surrogate host for Burkholderia pseudomallei, B. mallei and B. thailandensis
Published in BMC microbiology (22-06-2012)“…Burkholderia pseudomallei and Burkholderia mallei are gram-negative pathogens responsible for the diseases melioidosis and glanders, respectively. Both species…”
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Treatment of Experimental Anthrax with Recombinant Capsule Depolymerase
Published in Antimicrobial Agents and Chemotherapy (01-03-2008)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Burkholderia mallei tssM Encodes a Putative Deubiquitinase That Is Secreted and Expressed inside Infected RAW 264.7 Murine Macrophages
Published in Infection and Immunity (01-04-2009)“…Burkholderia mallei, a category B biothreat agent, is a facultative intracellular pathogen that causes the zoonotic disease glanders. The B. mallei VirAG…”
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Animal Pathogen-Like Type III Secretion System Is Required for the Intracellular Survival of Burkholderia mallei within J774.2 Macrophages
Published in Infection and Immunity (01-07-2006)“…Burkholderia mallei is a highly infectious gram-negative pathogen and is the causative agent of human and animal glanders. By generating polar mutations…”
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Time-Lapse Confocal Imaging of Development of Bacillus anthracis in Macrophages
Published in The Journal of infectious diseases (01-04-2004)“…Macrophages attempt to battle infection with Bacillus anthracis spores by phagocytosis of the spores. However, it is believed that B. anthracis spores may…”
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Binding Sites of Anti-Lcr V Monoclonal Antibodies Are More Critical than the Avidities and Affinities for Passive Protection against Yersinia pestis Infection in a Bubonic Plague Model
Published in Antibodies (Basel) (03-08-2020)“…Plague is a zoonotic disease that is caused by Yersinia pestis. Monoclonal antibodies (mAbs) that bind to the V-antigen, a virulence factor that is produced by…”
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Anthrax Lethal Toxin Impairs Innate Immune Functions of Alveolar Macrophages and Facilitates Bacillus anthracis Survival
Published in Infection and Immunity (01-09-2006)“…Alveolar macrophages (AM) are very important for pulmonary innate immune responses against invading inhaled pathogens because they directly kill the organisms…”
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Laser Scanning Confocal Microscopy Was Used to Validate the Presence of Burkholderia Pseudomallei or B. Mallei in Formalin-Fixed Paraffin Embedded Tissues
Published in Tropical medicine and infectious disease (29-04-2020)“…and are Gram-negative, facultative intracellular bacteria that cause melioidosis and glanders, respectively. Currently, there are no vaccines for these two…”
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Activity of the Bacillus anthracis 20 kDa protective antigen component
Published in BMC infectious diseases (22-09-2008)“…Anthrax is caused by Bacillus anthracis that produce two exotoxins, lethal toxin and edema toxin. The lethal toxin is composed of the lethal factor (LF)…”
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Human Innate Immune Cells Respond Differentially to Poly-γ-Glutamic Acid Polymers from Bacillus anthracis and Nonpathogenic Bacillus Species
Published in The Journal of immunology (1950) (01-03-2020)“…The poly-γ-glutamic acid (PGA) capsule produced by is composed entirely of d-isomer glutamic acid, whereas nonpathogenic species produce mixed d-, l-isomer…”
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In vitro intracellular trafficking of virulence antigen during infection by Yersinia pestis
Published in PloS one (17-07-2009)“…Yersinia pestis, the causative agent of plague, encodes several essential virulence factors on a 70 kb plasmid, including the Yersinia outer proteins (Yops)…”
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Protection of rhesus macaques against inhalational anthrax with a Bacillus anthracis capsule conjugate vaccine
Published in Vaccine (25-07-2016)“…Abstract The efficacy of currently licensed anthrax vaccines is largely attributable to a single Bacillus anthracis immunogen, protective antigen. To broaden…”
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Poly-γ-Glutamic Acid Encapsulation of Bacillus anthracis Inhibits Human Dendritic Cell Responses
Published in ImmunoHorizons (09-02-2021)“…The capsule of is composed of a d isomer poly-γ-glutamic acid polymer, which is especially nonstimulatory to dendritic cells, even more so than similar mixed…”
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Dendritic Cells Endocytose Bacillus anthracis Spores: Implications for Anthrax Pathogenesis
Published in The Journal of immunology (1950) (01-05-2005)“…Phagocytosis of inhaled Bacillus anthracis spores and subsequent trafficking to lymph nodes are decisive events in the progression of inhalational anthrax…”
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Multiple asparagine deamidation of Bacillus anthracis protective antigen causes charge isoforms whose complexity correlates with reduced biological activity
Published in Proteins, structure, function, and bioinformatics (01-08-2007)“…Protective antigen is essential for the pathology of Bacillus anthracis and is the proposed immunogen for an improved human anthrax vaccine. Known since…”
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Laser scanning confocal microscopy was used to validate the presence of 'Burkholderia pseudomallei' or 'B. mallei' in formalin-fixed paraffin embedded tissues
Published in Tropical medicine and infectious disease (01-06-2020)“…Burkholderia pseudomallei and B. mallei are Gram-negative, facultative intracellular bacteria that cause melioidosis and glanders, respectively. Currently,…”
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20
Activity of the Bacillus anthracis20 kDa protective antigen component
Published in BMC infectious diseases (22-09-2008)“…Abstract Background Anthrax is caused by Bacillus anthracis that produce two exotoxins, lethal toxin and edema toxin. The lethal toxin is composed of the…”
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