Search Results - "Wilson, Sean M"
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1
Editorial: The role of pericytes in physiology and pathophysiology
Published in Frontiers in physiology (2023)Get full text
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2
Improved Workflow for Analysis of Vascular Myocyte Time-Series and Line-Scan Ca2+ Imaging Datasets
Published in International journal of molecular sciences (04-06-2023)“…Intracellular Ca2+ signals are key for the regulation of cellular processes ranging from myocyte contraction, hormonal secretion, neural transmission, cellular…”
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3
The Effects of Insulin-Like Growth Factor I and BTP-2 on Acute Lung Injury
Published in International journal of molecular sciences (15-05-2021)“…Acute lung injury (ALI) afflicts approximately 200,000 patients annually and has a 40% mortality rate. The COVID-19 pandemic has massively increased the rate…”
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4
Gestational long-term hypoxia induces metabolomic reprogramming and phenotypic transformations in fetal sheep pulmonary arteries
Published in American journal of physiology. Lung cellular and molecular physiology (01-05-2021)“…Gestational long-term hypoxia increases the risk of myriad diseases in infants including persistent pulmonary hypertension. Similar to humans, fetal lamb lung…”
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5
Chronic Hypoxia Suppresses Pregnancy-Induced Upregulation of Large-Conductance Ca2+-Activated K+ Channel Activity in Uterine Arteries
Published in Hypertension (Dallas, Tex. 1979) (01-07-2012)“…Our previous study demonstrated that increased Ca-activated K (BKCa) channel activity played a key role in the normal adaptation of reduced myogenic tone of…”
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Chronic hypoxia during gestation enhances uterine arterial myogenic tone via heightened oxidative stress
Published in PloS one (16-09-2013)“…Chronic hypoxia during gestation has profound adverse effects on the adaptation of uteroplacental circulation in pregnancy. Yet, the underlying mechanisms are…”
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Can Maternal Exercise Prevent High-Altitude Pulmonary Hypertension in Children?
Published in High altitude medicine & biology (01-03-2023)“…Leslie, Eric, Ann L. Gibson, Laura V. Gonzalez Bosc, Christine Mermier, Sean M. Wilson, and Michael R. Deyhle. Review: can maternal exercise prevent…”
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8
CaV3.2 Channels and the Induction of Negative Feedback in Cerebral Arteries
Published in Circulation research (12-09-2014)“…RATIONALE:T-type (CaV3.1/CaV3.2) Ca channels are expressed in rat cerebral arterial smooth muscle. Although present, their functional significance remains…”
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Defective bone repletion in aged Balb/cBy mice was caused by impaired osteoblastic differentiation
Published in Journal of bone and mineral metabolism (01-11-2022)“…Introduction This study was undertaken to gain mechanistic information about bone repair using the bone repletion model in aged Balb/cBy mice. Materials and…”
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10
Long-Term Hypoxia Negatively Influences Ca2+ Signaling in Basilar Arterial Myocytes of Fetal and Adult Sheep
Published in Frontiers in physiology (18-01-2022)“…Cerebral arterial vasoreactivity is vital to the regulation of cerebral blood flow. Depolarization of arterial myocytes elicits whole-cell Ca 2+ oscillations…”
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11
Gestational Hypoxia and Programing of Lung Metabolism
Published in Frontiers in physiology (29-11-2019)“…Gestational hypoxia is a risk factor in the development of pulmonary hypertension in the newborn and other sequela, however, the mechanisms associated with the…”
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Long-Term High-Altitude Hypoxia and Alpha Adrenoceptor-Dependent Pulmonary Arterial Contractions in Fetal and Adult Sheep
Published in Frontiers in physiology (28-08-2019)“…Autonomic innervation of the pulmonary vasculature triggers vasomotor contractility predominately through activation of alpha-adrenergic receptors (α-ARs) in…”
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13
Middle school cycling program is associated with improved mental health and wellbeing in adolescents during COVID-19
Published in Frontiers in sports and active living (12-10-2023)“…The COVID-19 pandemic has exacerbated mental health issues among adolescents. Exercise is well-regarded for boosting mental health. Riding for Focus (R4F) is a…”
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14
Direct Dry Air Capture of CO2 Using VTSA with Faujasite Zeolites
Published in Industrial & engineering chemistry research (06-05-2020)“…The capture and concentration of CO2 from a dry ambient air stream by temperature vacuum swing adsorption (TVSA) have been experimentally demonstrated on a…”
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15
Antenatal hypoxia and pulmonary vascular function and remodeling
Published in Current vascular pharmacology (01-09-2013)“…This review provides evidence that antenatal hypoxia, which represents a significant and worldwide problem, causes prenatal programming of the lung. A general…”
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16
Updating the Assignment of Levels of Evidence
Published in Journal of bone and joint surgery. American volume (07-01-2015)Get full text
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17
Role of blood and vascular smooth muscle in the vasoactivity of nitrite
Published in American journal of physiology. Heart and circulatory physiology (01-10-2014)“…Recent evidence from humans and rats indicates that nitrite is a vasodilator under hypoxic conditions by reacting with metal-containing proteins to produce…”
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Mobilization of sarcoplasmic reticulum stores by hypoxia leads to consequent activation of capacitative Ca2+ entry in isolated canine pulmonary arterial smooth muscle cells
Published in The Journal of physiology (01-03-2005)“…Capacitative Ca 2+ entry (CCE) has been speculated to contribute to Ca 2+ influx during hypoxic pulmonary vasoconstriction (HPV). The aim of the present study…”
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Heterogeneity of calcium stores and elementary release events in canine pulmonary arterial smooth muscle cells
Published in American Journal of Physiology: Cell Physiology (01-01-2001)“…To examine the nature of inositol 1,4,5-trisphosphate (IP(3))-sensitive and ryanodine (Ryn)-sensitive Ca(2+) stores in isolated canine pulmonary arterial…”
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Ryanodine receptor subtypes regulate Ca2+ sparks/spontaneous transient outward currents and myogenic tone of uterine arteries in pregnancy
Published in Cardiovascular research (22-02-2021)“…Abstract Aims Our recent study demonstrated that increased Ca2+ sparks and spontaneous transient outward currents (STOCs) played an important role in uterine…”
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