Search Results - "Wilson, Sarah F."

Pharmacokinetics, Biotransformation, and Excretion of [14C]Etelcalcetide (AMG 416) Following a Single Microtracer Intravenous Dose in Patients with Chronic Kidney Disease on Hemodialysis by Subramanian, Raju, Zhu, Xiaochun, Hock, M. Benjamin, Sloey, Bethlyn J., Wu, Benjamin, Wilson, Sarah F., Egbuna, Ogo, Slatter, J. Greg, Xiao, Jim, Skiles, Gary L.

“…Etelcalcetide (AMG 416) is a novel synthetic peptide calcium-sensing receptor activator in clinical development as an intravenous calcimimetic for the…”
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Nonclinical Pharmacokinetics, Disposition, and Drug-Drug Interaction Potential of a Novel d-Amino Acid Peptide Agonist of the Calcium-Sensing Receptor AMG 416 (Etelcalcetide) by Subramanian, Raju, Zhu, Xiaochun, Kerr, Savannah J, Esmay, Joel D, Louie, Steven W, Edson, Katheryne Z, Walter, Sarah, Fitzsimmons, Michael, Wagner, Mylo, Soto, Marcus, Pham, Roger, Wilson, Sarah F, Skiles, Gary L

“…AMG 416 (etelcalcetide) is a novel synthetic peptide agonist of the calcium-sensing receptor composed of a linear chain of seven d-amino acids (referred to as…”
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Validation of a method for the determination of AMG 579 in cerebrospinal fluid with a focus on sample collection procedures for clinical trials by Wilson, Sarah F., Kerr, Savannah J., Rose, Mark J., James, Christopher A.

“…•Molecules can non-specifically bind to surfaces thus reducing their recovery in low protein matrices such as CSF.•When sampling CSF in the clinic, potential…”
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Development of a method for the determination of glycine in human cerebrospinal fluid using pre-column derivatization and LC–MS/MS by Wilson, Sarah F., James, Christopher A., Zhu, Xiaochun, Davis, Mike T., Rose, Mark J.

“…An LC–MS/MS method using pre-column derivatization with phenylisothiocyanate (PITC) was developed to quantify glycine in human cerebrospinal fluid (CSF) and…”
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Time Course of Pupil Center Location after Ocular Drug Application by Hoang, Tony A, Macdonnell, Jacqueline E, Mangan, Michelle C, Monsour, Cindy S, Polwattage, Buddhika L, Wilson, Sarah F, Suheimat, Marwan, Atchison, David A

“…PURPOSETo investigate the time course of pupil centration after application of common topical ocular drugs. METHODSSingle drops of 2.5% phenylephrine…”
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Concentration Profiling in Rat Tissue by High-Resolution Magic-Angle Spinning NMR Spectroscopy:  Investigation of a Model Drug by Lucas, Laura H, Wilson, Sarah F, Lunte, Craig E, Larive, Cynthia K

“…The utility of high-resolution magic-angle spinning (HR-MAS) NMR for studying drug delivery in whole tissues was explored by dosing female Sprague−Dawley rats…”
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North American ginseng influences adipocyte–macrophage crosstalk regulation of inflammatory gene expression by Garbett, Jaime, Wilson, Sarah A.F., Ralston, Jessica C., De Boer, Anna A., Lui, Ed M.K., Wright, David C., Mutch, David M.

“…Adipocyte–macrophage communication plays a critical role regulating white adipose tissue (WAT) inflammatory gene expression. Because WAT inflammation…”
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