Search Results - "Wilson, Robert L"

Direct chemical evidence for sphingolipid domains in the plasma membranes of fibroblasts by Frisz, Jessica F, Lou, Kaiyan, Klitzing, Haley A, Hanafin, William P, Lizunov, Vladimir, Wilson, Robert L, Carpenter, Kevin J, Kim, Raehyun, Hutcheon, Ian D, Zimmerberg, Joshua, Weber, Peter K, Kraft, Mary L

“…Sphingolipids play important roles in plasma membrane structure and cell signaling. However, their lateral distribution in the plasma membrane is poorly…”
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In vivo intervertebral disc deformation: intratissue strain patterns within adjacent discs during flexion–extension by Wilson, Robert L., Bowen, Leah, Kim, Woong, Cai, Luyao, Schneider, Stephanie Ellyse, Nauman, Eric A., Neu, Corey P.

“…The biomechanical function of the intervertebral disc (IVD) is a critical indicator of tissue health and pathology. The mechanical responses (displacements,…”
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Hemagglutinin Clusters in the Plasma Membrane Are Not Enriched with Cholesterol and Sphingolipids by Wilson, Robert L., Frisz, Jessica F., Klitzing, Haley A., Zimmerberg, Joshua, Weber, Peter K., Kraft, Mary L.

“…The clusters of the influenza envelope protein, hemagglutinin, within the plasma membrane are hypothesized to be enriched with cholesterol and sphingolipids…”
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Oral Vaccination Approaches for Anti-SHIV Immunity by Velarde de la Cruz, Erandi, Wang, Lingyun, Bose, Deepanwita, Gangadhara, Sailaja, Wilson, Robert L, Amara, Rama R, Kozlowski, Pamela A, Aldovini, Anna

“…We modified a Sabin Oral Poliovirus Vaccine (OPV) vector to permit secretion of the antigens of interest with the goal of improving anti-HIV Env humoral…”
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Resistance to Infection, Early and Persistent Suppression of Simian Immunodeficiency Virus SIVmac251 Viremia, and Significant Reduction of Tissue Viral Burden after Mucosal Vaccination in Female Rhesus Macaques by Manrique, Mariana, Kozlowski, Pamela A, Cobo-Molinos, Antonio, Wang, Shainn-Wei, Wilson, Robert L, Martinez-Viedma, Maria del Pilar, Montefiori, David C, Carville, Angela, Aldovini, Anna

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Immunogenicity of a Vaccine Regimen Composed of Simian Immunodeficiency Virus DNA, rMVA, and Viral Particles Administered to Female Rhesus Macaques via Four Different Mucosal Routes by Manrique, Mariana, Kozlowski, Pamela A, Cobo-Molinos, Antonio, Wang, Shainn-Wei, Wilson, Robert L, Montefiori, David C, Carville, Angela, Aldovini, Anna

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Genetic immunization in the lung induces potent local and systemic immune responses by Song, Kaimei, Bolton, Diane L., Wilson, Robert L., Camp, Jeremy V., Bao, Saran, Mattapallil, Joseph J., Herzenberg, Leonore A., Herzenberg, Leonard A., Andrews, Charla A., Sadoff, Jerald C., Goudsmit, Jaap, Pau, Maria Grazia, Seder, Robert A., Kozlowski, Pamela A., Nabel, Gary J., Roederer, Mario, Rao, Srinivas S.

“…Successful vaccination against respiratory infections requires elicitation of high levels of potent and durable humoral and cellular responses in the lower…”
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Invaplex functions as an intranasal adjuvant for subunit and DNA vaccines co-delivered in the nasal cavity of nonhuman primates by Camp, Jeremy V., Wilson, Robert L., Singletary, Morgan, Blanchard, James L., Aldovini, Anna, Kaminski, Robert W., Oaks, Edwin V., Kozlowski, Pamela A.

“…Development of intranasal vaccines for HIV-1 and other mucosal pathogens has been hampered by the lack of adjuvants that can be given safely to humans. We have…”
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In vivo human knee varus-valgus loading apparatus for analysis of MRI-based intratissue strain and relaxometry by Zhu, Hongtian, Miller, Emily Y., Lee, Woowon, Wilson, Robert L., Neu, Corey P.

“…The diagnosis of early-stage osteoarthritis remains as an unmet challenge in medicine and a roadblock to evaluating the efficacy of disease-modifying…”
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Spatial Gradients of Quantitative MRI as Biomarkers for Early Detection of Osteoarthritis: Data From Human Explants and the Osteoarthritis Initiative by Wilson, Robert L., Emery, Nancy C., Pierce, David M., Neu, Corey P.

“…Background Healthy articular cartilage presents structural gradients defined by distinct zonal patterns through the thickness, which may be disrupted in the…”
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Raman spectroscopy–based water measurements identify the origin of MRI T2 signal in human articular cartilage zones and predict histopathologic score by Unal, Mustafa, Wilson, Robert L., Neu, Corey P., Akkus, Ozan

“…We investigated for the first time zonal‐dependent water distribution in articular cartilage by Raman spectroscopy (RS). We further investigated the…”
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Envelope-Modified Single-Cycle Simian Immunodeficiency Virus Selectively Enhances Antibody Responses and Partially Protects against Repeated, Low-Dose Vaginal Challenge by Alpert, Michael D, Rahmberg, Andrew R, Neidermyer, William, Ng, Sharon K, Carville, Angela, Camp, Jeremy V, Wilson, Robert L, Piatak, Jr, Michael, Mansfield, Keith G, Li, Wenjun, Miller, Christopher J, Lifson, Jeffrey D, Kozlowski, Pamela A, Evans, David T

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Performance measures in Friedreich ataxia: Potential utility as clinical outcome tools by Lynch, David R., Farmer, Jennifer M., Wilson, Robert L., Balcer, Laura J.

“…Although several neuroprotective agents have been proposed as potential therapies in Friedreich ataxia (FA), clinical trials of their efficacy are limited by a…”
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Organizational resilience as a human capital strategy for companies in bankruptcy by Wilson, Robert L

“…Bankruptcy is a crisis that generates severe stress and anxiety, resulting in maladaptive behavior and inappropriate decision-making at both individual and…”
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Dynamic biophysical responses of neuronal cell nuclei and cytoskeletal structure following high impulse loading by Schneider, Stephanie E., Scott, Adrienne K., Seelbinder, Benjamin, Elzen, Courtney Van Den, Wilson, Robert L., Miller, Emily Y., Beato, Quinn I., Ghosh, Soham, Barthold, Jeanne E., Bilyeu, Jason, Emery, Nancy C., Pierce, David M., Neu, Corey P.

“…Cells are continuously exposed to dynamic environmental cues that influence their behavior. Mechanical cues can influence cellular and genomic architecture,…”
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Quantifying the Molar Percentages of Cholesterol in Supported Lipid Membranes by Time-of-Flight Secondary Ion Mass Spectrometry and Multivariate Analysis by Wilson, Robert L, Kraft, Mary L

“…The uneven cholesterol distribution among organelles and within the plasma membrane is postulated to be critical for proper cellular function. To study how…”
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Long-Term Control of Simian Immunodeficiency Virusmac251 Viremia to Undetectable Levels in Half of Infected Female Rhesus Macaques Nasally Vaccinated with Simian Immunodeficiency Virus DNA/Recombinant Modified Vaccinia Virus Ankara by Manrique, Mariana, Kozlowski, Pamela A., Cobo-Molinos, Antonio, Wang, Shainn-Wei, Wilson, Robert L., Montefiori, David C., Mansfield, Keith G., Carville, Angela, Aldovini, Anna

“…The efficacy of two SIV DNA plus recombinant modified vaccinia virus Ankara nasal vaccine regimens, one combined with plasmids expressing IL-2 and IL-15, the…”
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Identifying Differentiation Stage of Individual Primary Hematopoietic Cells from Mouse Bone Marrow by Multivariate Analysis of TOF-Secondary Ion Mass Spectrometry Data by Frisz, Jessica F, Choi, Ji Sun, Wilson, Robert L, Harley, Brendan A. C, Kraft, Mary L

“…The ability to self-renew and differentiate into multiple types of blood and immune cells renders hematopoietic stem and progenitor cells (HSPCs) valuable for…”
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Fluorinated Colloidal Gold Immunolabels for Imaging Select Proteins in Parallel with Lipids Using High-Resolution Secondary Ion Mass Spectrometry by Wilson, Robert L, Frisz, Jessica F, Hanafin, William P, Carpenter, Kevin J, Hutcheon, Ian D, Weber, Peter K, Kraft, Mary L

“…The local abundance of specific lipid species near a membrane protein is hypothesized to influence the protein’s activity. The ability to simultaneously image…”
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Preexisting vaccinia virus immunity decreases SIV-specific cellular immunity but does not diminish humoral immunity and efficacy of a DNA/MVA vaccine by Kannanganat, Sunil, Nigam, Pragati, Velu, Vijayakumar, Earl, Patricia L, Lai, Lilin, Chennareddi, Lakshmi, Lawson, Benton, Wilson, Robert L, Montefiori, David C, Kozlowski, Pamela A, Moss, Bernard, Robinson, Harriet L, Amara, Rama Rao

“…The influence of preexisting immunity to viral vectors is a major issue for the development of viral-vectored vaccines. In this study, we investigate the…”
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