Search Results - "Wilson, R.K."

IRF6 mutation screening in non-syndromic orofacial clefting: analysis of 1521 families by Leslie, E.J., Koboldt, D.C., Kang, C.J., Ma, L., Hecht, J.T., Wehby, G.L., Christensen, K., Czeizel, A.E., Deleyiannis, F.W.-B., Fulton, R.S., Wilson, R.K., Beaty, T.H., Schutte, B.C., Murray, J.C., Marazita, M.L.

“…Van der Woude syndrome (VWS) is an autosomal dominant malformation syndrome characterized by orofacial clefting (OFC) and lower lip pits. The clinical…”
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Targetable Kinase-Activating Lesions in Ph-like Acute Lymphoblastic Leukemia by Roberts, Kathryn G, Li, Yongjin, Payne-Turner, Debbie, Harvey, Richard C, Yang, Yung-Li, Pei, Deqing, McCastlain, Kelly, Ding, Li, Lu, Charles, Song, Guangchun, Ma, Jing, Becksfort, Jared, Rusch, Michael, Chen, Shann-Ching, Easton, John, Cheng, Jinjun, Boggs, Kristy, Santiago-Morales, Natalia, Iacobucci, Ilaria, Fulton, Robert S, Wen, Ji, Valentine, Marcus, Cheng, Cheng, Paugh, Steven W, Devidas, Meenakshi, Chen, I-Ming, Reshmi, Shalini, Smith, Amy, Hedlund, Erin, Gupta, Pankaj, Nagahawatte, Panduka, Wu, Gang, Chen, Xiang, Yergeau, Donald, Vadodaria, Bhavin, Mulder, Heather, Winick, Naomi J, Larsen, Eric C, Carroll, William L, Heerema, Nyla A, Carroll, Andrew J, Grayson, Guy, Tasian, Sarah K, Moore, Andrew S, Keller, Frank, Frei-Jones, Melissa, Whitlock, James A, Raetz, Elizabeth A, White, Deborah L, Hughes, Timothy P, Guidry Auvil, Jaime M, Smith, Malcolm A, Marcucci, Guido, Bloomfield, Clara D, Mrózek, Krzysztof, Kohlschmidt, Jessica, Stock, Wendy, Kornblau, Steven M, Konopleva, Marina, Paietta, Elisabeth, Pui, Ching-Hon, Jeha, Sima, Relling, Mary V, Evans, William E, Gerhard, Daniela S, Gastier-Foster, Julie M, Mardis, Elaine, Wilson, Richard K, Loh, Mignon L, Downing, James R, Hunger, Stephen P, Willman, Cheryl L, Zhang, Jinghui, Mullighan, Charles G

“…About 25% of young adults with ALL have Ph-like genotypes, which are associated with poor outcomes with conventional treatment. In this gene-expression study,…”
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Clonal diversity of recurrently mutated genes in myelodysplastic syndromes by Walter, M J, Shen, D, Shao, J, Ding, L, White, B S, Kandoth, C, Miller, C A, Niu, B, McLellan, M D, Dees, N D, Fulton, R, Elliot, K, Heath, S, Grillot, M, Westervelt, P, Link, D C, DiPersio, J F, Mardis, E, Ley, T J, Wilson, R K, Graubert, T A

“…Recent studies suggest that most cases of myelodysplastic syndrome (MDS) are clonally heterogeneous, with a founding clone and multiple subclones. It is not…”
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Epigenomic analysis of the HOX gene loci reveals mechanisms that may control canonical expression patterns in AML and normal hematopoietic cells by Spencer, D H, Young, M A, Lamprecht, T L, Helton, N M, Fulton, R, O'Laughlin, M, Fronick, C, Magrini, V, Demeter, R T, Miller, C A, Klco, J M, Wilson, R K, Ley, T J

“…HOX genes are highly expressed in many acute myeloid leukemia (AML) samples, but the patterns of expression and associated regulatory mechanisms are not…”
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Clonal evolution revealed by whole genome sequencing in a case of primary myelofibrosis transformed to secondary acute myeloid leukemia by Engle, E K, Fisher, D A C, Miller, C A, McLellan, M D, Fulton, R S, Moore, D M, Wilson, R K, Ley, T J, Oh, S T

“…Clonal architecture in myeloproliferative neoplasms (MPNs) is poorly understood. Here we report genomic analyses of a patient with primary myelofibrosis (PMF)…”
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The DNA double-strand break response is abnormal in myeloblasts from patients with therapy-related acute myeloid leukemia by Jacoby, M A, De Jesus Pizarro, R E, Shao, J, Koboldt, D C, Fulton, R S, Zhou, G, Wilson, R K, Walter, M J

“…The complex chromosomal aberrations found in therapy-related acute myeloid leukemia (t-AML) suggest that the DNA double-strand break (DSB) response may be…”
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Sequencing of the human IG light chain loci from a hydatidiform mole BAC library reveals locus-specific signatures of genetic diversity by Watson, C T, Steinberg, K M, Graves, T A, Warren, R L, Malig, M, Schein, J, Wilson, R K, Holt, R A, Eichler, E E, Breden, F

“…Germline variation at immunoglobulin (IG) loci is critical for pathogen-mediated immunity, but establishing complete haplotype sequences in these regions has…”
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Targeted sequencing informs the evaluation of normal karyotype cytopenic patients for low-grade myelodysplastic syndrome by Duncavage, E J, O'Brien, J, Vij, K, Miller, C A, Chang, G S, Shao, J, Jacoby, M A, Heath, S, Janke, M R, Elliott, K, Fulton, R S, Fronick, C, O'Laughlin, M, Westervelt, P, Ley, T J, Wilson, R K, Walter, M J

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Recurrent injury patterns in adolescent rugby by Archbold, H.A.P., Rankin, A.T., Webb, M., Nicholas, R., Eames, N.W.A., Wilson, R.K., Henderson, L.A., Heyes, G.J., Davies, R., Bleakley, C.M.

“…To establish patterns of subsequent injury in U18 rugby, to quantify the burden of within season injury recurrence. Secondary analysis of prospective data. 28…”
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Collaboration in Context: Rural Change and Community Forestry in the Four Corners by Wilson, R.K

“…Over the past decade, many rural communities in the western United States have experienced dramatic social and economic transformations. Concurrent with these…”
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Genetic association between the APOE4 allele and Lewy bodies in Alzheimer disease by TSUANG, D. W, WILSON, R. K, LOPEZ, O. L, LUEDECKING-ZIMMER, E. K, LEVERENZ, J. B, DEKOSKY, S. T, KAMBOH, M. I, HAMILTON, R. L

“…To explore the association between APOE*4 and pathologically confirmed cases of the Lewy body (LB) variant of Alzheimer disease (AD). With use of…”
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Identification and analysis of genes expressed in the adult filarial parasitic nematode Dirofilaria immitis by Yin, Yong, Martin, John, McCarter, James P., Clifton, Sandra W., Wilson, Richard K., Mitreva, Makedonka

“…The heartworm Dirofilaria immitis is a filarial parasitic nematode infecting dogs and other mammals worldwide causing fatal complications. Here, we present the…”
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Modification of a commercially available DNA sequencer to increase sample throughput by Stuebe, E.T., Steward, J.Q., Chinwalia, A., Cook, L.L., Cook, M., Fronick, B., Miller, K., Mullen, M.K., O'Brien, D., Panussis, D.A., Pohl, C., Snider, J.E., Strong, J., Williams, D., Wilson, R.K., Tibbets, C., Mardis, E.R.

“…Rather than wait for the instrument manufacturer to provide 96-lane-per-gel capability, the authors decided to further develop a modification proposed by Clark…”
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The cemented custom femoral stem--a 10 year review by O'Brien, S, Wilson, R K, Hanratty, B M, Thompson, N W, Wallace, M E, Nixon, J R, Engela, D W, Orr, J F, Isaac, G H, Beverland, D E

“…We report a series of 706 patients (759 hip implants) with an average follow up of 10.5 years (range, 10-11 years) following total hip replacement (THR) using…”
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The cemented custom femoral stem - a 10 year review by O'Brien, S., Wilson, R.K., Hanratty, B.M., Thompson, N.W., Wallace, M.E., Nixon, J.R., Engela, D.W., Orr, J.F., Isaac, G.H., Beverland, D.E.

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Preferential RNA editing at specific sites within transcripts of two plant mitochondrial genes does not depend on transcriptional context or nuclear genotype by Wilson, R.K, Hanson, M.R

“…Transcripts of most plant mitochondrial protein-coding genes exhibit C-to-U RNA editing events. In Petunia, two co-transcribed genes, nad3 and rps12, exhibit…”
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Mutational profiling in the human genome by Wilson, R K, Ley, T J, Cole, F S, Milbrandt, J D, Clifton, S, Fulton, L, Fewell, G, Minx, P, Sun, H, McLellan, M, Pohl, C, Mardis, E R

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Fatal hepatic sarcocystosis in two polar bears (Ursus maritimus) by Garner, M.M, Barr, B.C, Packham, A.E, Marsh, A.E, Burek-Huntington, K.A, Wilson, R.K, Dubey, J.P

“…Fatal hepatic sarcocystosis was diagnosed in 2 polar bears from a zoo in Anchorage, Alaska. Gross lesions were icterus and systemic petechiae. Marked…”
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The human genome: genes, pseudogenes, and variation on chromosome 7 by Waterston, R H, Hillier, L W, Fulton, L A, Fulton, R S, Graves, T A, Pepin, K H, Bork, P, Suyama, M, Torrents, D, Chinwalla, A T, Mardis, E R, McPherson, J D, Wilson, R K

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Identification, characterization, and mapping of a mouse homolog of the gene mutated in Nijmegen breakage syndrome by Vissinga, C S, Yeo, T C, Woessner, J, Massa, H F, Wilson, R K, Trask, B J, Concannon, P

“…The rare autosomal recessive disorder Nijmegen breakage syndrome (NBS) results from mutations in the NBS1 gene on human chromosome 8q21. A mouse homolog of the…”
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