Search Results - "Wilson, R. J. M"
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Parasite plastids: approaching the endgame
Published in Biological reviews of the Cambridge Philosophical Society (01-02-2005)“…Considerable work still needs to be done to understand more fully the basic processes going on inside the non-photosynthetic plastid organelle of Plasmodium…”
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A Plastid of Probable Green Algal Origin in Apicomplexan Parasites
Published in Science (American Association for the Advancement of Science) (07-03-1997)“…Protozoan parasites of the phylum Apicomplexa contain three genetic elements: the nuclear and mitochondrial genomes characteristic of virtually all eukaryotic…”
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The plastid of Plasmodium spp.: a target for inhibitors
Published in Current topics in microbiology and immunology (2005)“…Determined efforts are being made to explore the non-photosynthetic plastid organelle of Plasmodium falciparum as a target for drug development. Certain…”
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Nifs and Sufs in malaria
Published in Molecular microbiology (01-09-2001)“…This review assembles data from three bodies of literature (bacterial genetics, plastid biogenesis and parasitology) that seldom have much direct cross‐talk…”
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The plastid DNA of the malaria parasite Plasmodium falciparum is replicated by two mechanisms
Published in Molecular microbiology (01-07-2002)“…Summary In common with other apicomplexan parasites, Plasmodium falciparum, a causative organism of human malaria, harbours a residual plastid derived from an…”
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Proteobacteria-like ferrochelatase in the malaria parasite
Published in Current genetics (01-02-2003)“…A gene encoding the heme biosynthetic enzyme ferrochelatase (FC) was found in the genomic DNA databases of Plasmodium spp. The predicted amino acid sequence of…”
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Parasite plastids: maintenance and functions
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (29-01-2003)“…genes have emerged only recently and point to the areas of iron homeostasis, [Fe–S] cluster formation and oxidative stress. We present experimental evidence…”
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Hydrodynamic characterization of the SufBC and SufCD complexes and their interaction with fluorescent adenosine nucleotides
Published in Protein science (01-07-2008)“…Bacteria, as well as the plastid organelles of algae and higher plants, utilize proteins of the suf operon. These are involved in Fe‐S cluster assembly,…”
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Enzymes for Heme Biosynthesis are Found in Both the Mitochondrion and Plastid of the Malaria Parasite Plasmodium falciparum
Published in Protist (01-03-2004)“…All eight enzymes required for de novo heme biosynthesis have been predicted from the nuclear genome of the human malaria parasite Plasmodium falciparum. We…”
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Kinetic Mechanism of the SufC ATPase: THE CLEAVAGE STEP IS ACCELERATED BY SufB
Published in The Journal of biological chemistry (31-03-2006)“…Protein products of the suf operon are involved in iron-sulfur metabolism. SufC is an ATPase that can interact with SufB in the absence of nucleotide. We have…”
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Red cell membrane protein distribution during malarial invasion
Published in Journal of cell science (01-04-1989)“…Immuno-gold labelling electron microscopy of thin sections was used to determine the distribution of red cell membrane and membrane skeleton proteins in the…”
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Transferability of first principles derived torsional potentials for mesogenic molecules and fragments
Published in Molecular physics (01-04-1998)“…The transferability of torsional potentials governing molecular flexibility is investigated using first principles density functional calculations. We aim to…”
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Plastid Functions in the Apicomplexa
Published in Protist (01-03-2004)Get full text
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Spotlight: Re-evaluating Replicating Organelles
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Origins of the parasitophorous vacuole membrane of the malaria parasite, Plasmodium falciparum, in human red blood cells
Published in Journal of cell science (01-07-1992)“…We have attempted to determine whether the parasitophorous vacuole membrane, in which the malaria parasite (merozoite) encapsulates itself when it enters a red…”
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Progress with Parasite Plastids
Published in Journal of molecular biology (31-05-2002)“…This review offers a snapshot of our current understanding of the origin, biology, and metabolic significance of the non-photosynthetic plastid organelle found…”
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Control of malarial invasion by phosphorylation of the host cell membrane cytoskeleton
Published in Nature (London) (27-11-1986)“…It has been shown that the entry of the malaria parasite into the red blood cell requires the presence of ATP in the host cell cytoplasm. In red blood cell…”
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Serotyping Plasmodium falciparum malaria with S-antigens
Published in Nature (London) (03-04-1980)“…The heat-stable proteins known as S-antigens which are associated with Plasmodium falciparum malarial infections in man show considerable serological…”
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Cellular mechanism for the protective effect of haemoglobin S against P. falciparum malaria
Published in Nature (London) (17-08-1978)Get full text
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The increased susceptibility of young red cells to invasion by the malarial parasite Plasmodium falciparum
Published in British journal of haematology (01-06-1980)“…The relationship between red cell age and susceptibility to invasion by the malarial parasite Plasmodium falciparum has been examined by several different…”
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