Search Results - "Wilson, J X"

Glucose modulates vitamin C transport in adult human small intestinal brush border membrane vesicles by Malo, C, Wilson, J X

“…The uptake of L-ascorbate (vitamin C) and its oxidized form, dehydro-L-ascorbic acid (DHAA), was evaluated in brush border membrane vesicles isolated from…”
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Antioxidant defense of the brain: a role for astrocytes by Wilson, J X

“…Partially reduced forms of oxygen are produced in the brain during cellular respiration and, at accelerated rates, during brain insults. The most reactive…”
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Glutamate stimulates ascorbate transport by astrocytes by Wilson, John X, Peters, Caralei E, Sitar, Sandra M, Daoust, Patrick, Gelb, Adrian W

“…The concentrations of glutamate and ascorbate in brain extracellular fluid increase following seizure activity, trauma and ischemia. Extracellular ascorbate…”
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Prooxidant activity and cellular effects of the phenoxyl radicals of dietary flavonoids and other polyphenolics by Galati, Giuseppe, Sabzevari, Omid, Wilson, John X, O'Brien, Peter J

“…Dietary polyphenolics in fruits, vegetables, wines, spices and herbal medicines have beneficial antioxidant, anti-inflammatory and anticancer effects. However,…”
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Requirement for Na(+)-dependent ascorbic acid transport in osteoblast function by Franceschi, R T, Wilson, J X, Dixon, S J

“…Ascorbic acid is necessary for expression of the osteoblast phenotype. We examined whether Na(+)-dependent transport is required for MC3T3-E1 preosteoblast…”
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Ascorbate transport and intracellular concentration in cerebral astrocytes by Siushansian, R, Wilson, J X

“…Regulation of the initial rate of uptake and steady-state concentration of ascorbate (reduced vitamin C) was investigated in rat cerebral astrocytes. Although…”
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Propofol prevents peroxide-induced inhibition of glutamate transport in cultured astrocytes by SITAR, S. M, HANIFI-MOGHADDAM, P, GELB, A, CECHETTO, D. F, SIUSHANSIAN, R, WILSON, J. X

“…Glutamate transporters located in the plasma membrane of cerebral astrocytes take up excitatory neurotransmitters from the synaptic cleft. In diseases…”
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Insular cortex stimulation produces lethal cardiac arrhythmias: a mechanism of sudden death? by Oppenheimer, S M, Wilson, J X, Guiraudon, C, Cechetto, D F

“…The rat posterior insular cortex has recently been shown to possess cardiac chronotropic organization and therefore may be involved in cortical mechanisms of…”
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Cerebral Astrocytes Transport Ascorbic Acid and Dehydroascorbic Acid Through Distinct Mechanisms Regulated by Cyclic AMP by Siushansian, Ramin, Tao, Lei, Dixon, S. Jeffrey, Wilson, John X.

“…: Cerebral ischemia and trauma lead to rapid increases in cerebral concentrations of cyclic AMP and dehydroascorbic acid (DHAA; oxidized vitamin C), depletion…”
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Ascorbate uptake by microvascular endothelial cells of rat skeletal muscle by Wilson, J X, Dixon, S J, Yu, J, Nees, S, Tyml, K

“…In several systems, exogenous ascorbate (reduced vitamin C) has been shown to protect against microvascular injury induced by reactive oxygen species. Since…”
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The impact of genetic removal of GFAP and/or vimentin on glutamine levels and transport of glucose and ascorbate in astrocytes by PEKNY, M, ELIASSON, C, SIUSHANSIAN, R, MEI DING, DIXON, S. J, PEKNA, M, WILSON, J. X, HAMBERGER, A

“…The importance of the intermediate filament (IF) proteins glial fibrillary acidic protein (GFAP) and vimentin for astrocyte function was studied by…”
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Osmotic swelling stimulates ascorbate efflux from cerebral astrocytes by Siushansian, R, Dixon, S J, Wilson, J X

“…Ascorbate (reduced vitamin C) is an important enzyme cofactor, neuromodulator, and antioxidant that is stored at millimolar concentrations in the cytosol of…”
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Ascorbate concentration in osteoblastic cells is elevated by transforming growth factor-beta by Wilson, J X, Dixon, S J

“…Transforming growth factor-beta modulates the proliferation, differentiation, and synthetic activity of osteoblasts, but its mechanisms of action are not fully…”
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Mechanisms of action of corticotropin-releasing factor and other regulators of corticotropin release in rat pituitary cells by Aguilera, G, Harwood, J P, Wilson, J X, Morell, J, Brown, J H, Catt, K J

“…The role of cyclic AMP in the stimulation of corticotropin (ACTH) release by corticotropin-releasing factor (CRF), angiotensin II (AII), vasopressin (VP), and…”
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Ascorbic acid uptake by a high-affinity sodium-dependent mechanism in cultured rat astrocytes by Wilson, J X

“…Ascorbic acid (vitamin C) is synthesized in rodent liver, circulates in the blood, and is concentrated in the brain. Experiments were performed to characterize…”
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Expression of gap junction genes in astrocytes and C6 glioma cells by Naus, C C, Bechberger, J F, Caveney, S, Wilson, J X

“…The expression of the gap junction genes coding for the liver-type connexin32 and the heart-type connexin43 was examined in primary cultures of astrocytes and…”
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Anesthetics and cerebral ischemia--should we continue to dream the impossible dream? by Gelb, A W, Wilson, J X, Cechetto, D F

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Rilmenidine Elevates Cytosolic Free Calcium Concentration in Suspended Cerebral Astrocytes by Ozog, Mark A., Wilson, John X., Dixon, S. Jeffrey, Cechetto, David F.

“…: Rilmenidine, a ligand for imidazoline and α2‐adrenergic receptors, is neuroprotective following focal cerebral ischemia. We investigated the effects of…”
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Progress in clinical neurosciences: sepsis-associated encephalopathy: evolving concepts by Wilson, John X, Young, G Bryan

“…Systemic sepsis commonly produces brain dysfunction, sepsis-associated encephalopathy, which can vary from a transient, reversible encephalopathy to…”
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Ascorbate prevents microvascular dysfunction in the skeletal muscle of the septic rat by Armour, John, Tyml, Karel, Lidington, Darcy, Wilson, John X

“…Departments of 1  Physiology and 2  Medical Biophysics, University of Western Ontario, and 3  A. C. Burton Vascular Biology Laboratory, Lawson Health Research…”
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