Search Results - "Wilson, Heather L."

Conformational dynamics of α-synuclein and study of its intramolecular forces in the presence of selected compounds by Khatooni, Zahed, Akhtari, Keivan, Wilson, Heather L.

“…Protein misfolding and aggregation play crucial roles in amyloidogenic diseases through the self-assembly of intrinsically disordered proteins (IDPs) in type…”
Get full text

Understanding GroEL and DnaK Stress Response Proteins as Antigens for Bacterial Diseases by Fourie, Kezia R, Wilson, Heather L

“…Bacteria do not simply express a constitutive panel of proteins but they instead undergo dynamic changes in their protein repertoire in response to changes in…”
Get full text

Markers of the ageing macrophage: a systematic review and meta-analysis by Moss, Charlotte E, Phipps, Hew, Wilson, Heather L, Kiss-Toth, Endre

“…Ageing research is establishing macrophages as key immune system regulators that undergo functional decline. Due to heterogeneity between species and tissue…”
Get full text

Regulating STING in health and disease by Li, Yang, Wilson, Heather L, Kiss-Toth, Endre

“…The presence of cytosolic double-stranded DNA molecules can trigger multiple innate immune signalling pathways which converge on the activation of an…”
Get full text

Immune responses in the uterine mucosa: clues for vaccine development in pigs by Choudhary, Pooja, Magloire, Donaldson, Hamonic, Glenn, Wilson, Heather L

“…The immune system in the upper reproductive tract (URT) protects against sexually transmitted pathogens, while at the same time providing immune tolerance…”
Get full text

Human Neural Larva Migrans Caused by Ophidascaris robertsi Ascarid by Hossain, Mehrab E, Kennedy, Karina J, Wilson, Heather L, Spratt, David, Koehler, Anson, Gasser, Robin B, Slapeta, Jan, Hawkins, Carolyn A, Bandi, Hari Priya, Senanayake, Sanjaya N

“…We describe a case in Australia of human neural larva migrans caused by the ascarid Ophidascaris robertsi, for which Australian carpet pythons are definitive…”
Get full text

tmem33 is essential for VEGF-mediated endothelial calcium oscillations and angiogenesis by Savage, Aaron M., Kurusamy, Sathishkumar, Chen, Yan, Jiang, Zhen, Chhabria, Karishma, MacDonald, Ryan B., Kim, Hyejeong R., Wilson, Heather L., van Eeden, Fredericus J. M., Armesilla, Angel L., Chico, Timothy J. A., Wilkinson, Robert N.

“…Angiogenesis requires co-ordination of multiple signalling inputs to regulate the behaviour of endothelial cells (ECs) as they form vascular networks. Vascular…”
Get full text

Evidence for a common mucosal immune system in the pig by Wilson, Heather L., Obradovic, Milan R.

“…•There is evidence that the common mucosal immune system exists in pigs.•Vaccination at an easily accessible mucosal site may assist in providing protection at…”
Get full text

Experimental natural transmission (seeder pig) models for reproduction of swine dysentery by Parra-Aguirre, Juan, Nosach, Roman, Fernando, Champika, Hill, Janet E, Wilson, Heather L, Harding, John C. S

“…Swine dysentery is causally associated with Brachyspira hampsonii and B . hyodysenteriae infection. Given the importance of transmission models in…”
Get full text

Aging-related defects in macrophage function are driven by MYC and USF1 transcriptional programs by Moss, Charlotte E., Johnston, Simon A., Kimble, Joshua V., Clements, Martha, Codd, Veryan, Hamby, Stephen, Goodall, Alison H., Deshmukh, Sumeet, Sudbery, Ian, Coca, Daniel, Wilson, Heather L., Kiss-Toth, Endre

“…Macrophages are central innate immune cells whose function declines with age. The molecular mechanisms underlying age-related changes remain poorly understood,…”
Get full text

Tribbles-1 Expression and Its Function to Control Inflammatory Cytokines, Including Interleukin-8 Levels are Regulated by miRNAs in Macrophages and Prostate Cancer Cells by Niespolo, Chiara, Johnston, Jessica M, Deshmukh, Sumeet R, Satam, Swapna, Shologu, Ziyanda, Villacanas, Oscar, Sudbery, Ian M, Wilson, Heather L, Kiss-Toth, Endre

“…The pseudokinase controls cell function in a range of contexts, by regulating MAP kinase activation and mediating protein degradation the COP1 ubiquitin…”
Get full text

In vivo synthesis of bacterial amyloid curli contributes to joint inflammation during S. Typhimurium infection by Miller, Amanda L, Pasternak, J. Alex, Medeiros, Nicole J, Nicastro, Lauren K, Tursi, Sarah A, Hansen, Elizabeth G, Krochak, Ryan, Sokaribo, Akosiererem S, MacKenzie, Keith D, Palmer, Melissa B, Herman, Dakoda J, Watson, Nikole L, Zhang, Yi, Wilson, Heather L, Wilson, R. Paul, White, Aaron P, Tükel, Çagla, Knodler, Leigh, Tsolis, Renée M

“…Reactive arthritis, an autoimmune disorder, occurs following gastrointestinal infection with invasive enteric pathogens, such as Salmonella enterica. Curli, an…”
Get full text

Expression of pattern recognition receptors in porcine uterine epithelial cells in vivo and in culture by Hamonic, Glenn, Pasternak, J. Alex, Forsberg, Nikki M., Käser, Tobias, Wilson, Heather L.

“…•A number of pattern recognition receptors are expressed by porcine uterine epithelial cells.•TLR3 and TLR9 localize to the apical cell membrane and TLR4…”
Get full text

Myocarditis Caused by Human Parechovirus in Adult by Kong, Khai Lin, Lau, Jillian S Y, Goh, Su Mei, Wilson, Heather L, Catton, Mike, Korman, Tony M

“…The infectious etiology of myocarditis often remains unidentified. We report a case of myocarditis associated with human parechovirus (HPeV) infection in an…”
Get full text

Development of flow cytometry based adherence assay for Neisseria gonorrhoeae using 5'-carboxyfluorosceinsuccidyl ester by Thakur, Sidharath Dev, Obradovic, Milan, Dillon, Jo-Anne R, Ng, Siew Hon, Wilson, Heather L

“…Neisseria gonorrhoeae is an obligate human pathogen and its adherence to host cells is essential for its pathogenesis. Gonococcal adherence assays are based on…”
Get full text

Zebrafish tissue injury causes upregulation of interleukin-1 and caspase-dependent amplification of the inflammatory response by Ogryzko, Nikolay V, Hoggett, Emily E, Solaymani-Kohal, Sara, Tazzyman, Simon, Chico, Timothy J A, Renshaw, Stephen A, Wilson, Heather L

“…Interleukin-1 (IL-1), the 'gatekeeper' of inflammation, is the apical cytokine in a signalling cascade that drives the early response to injury or infection…”
Get full text

Polyphosphazenes as Adjuvants for Animal Vaccines and Other Medical Applications by Chand, Dylan J, Magiri, Royford B, Wilson, Heather L, Mutwiri, George K

“…Polyphosphazenes are a class of experimental adjuvants that have shown great versatility as vaccine adjuvants in many animal species ranging from laboratory…”
Get full text

Assessment of Immunological Response and Impacts on Fertility Following Intrauterine Vaccination Delivered to Swine in an Artificial Insemination Dose by Hamonic, Glenn, Pasternak, J Alex, Ng, Siew Hon, Fourie, Kezia R, Simko, Olena M, Deluco, Brodie, Wilson, Heather L

“…To protect the health of sows and gilts, significant investments are directed toward the development of vaccines against infectious agents that impact…”
Get full text

Rearing pigs with play opportunities: the effects on disease resilience in pigs experimentally inoculated with PRRSV by Steinerová, Karolína, Harding, John C S, Parker, Sarah E, Wilson, Heather L, Nery Finatto, Arthur, Seddon, Yolande M

“…Positive emotions can reduce disease susceptibility during infectious challenges in humans, and emerging evidence suggests similar effects in farm animals…”
Get full text

A Modular, Tn7-Based System for Making Bioluminescent or Fluorescent Salmonella and Escherichia coli Strains by Shivak, Dylan J, MacKenzie, Keith D, Watson, Nikole L, Pasternak, J Alex, Jones, Brian D, Wang, Yejun, DeVinney, Rebekah, Wilson, Heather L, Surette, Michael G, White, Aaron P

“…Our goal was to develop a robust tagging method that can be used to track bacterial strains in vivo To address this challenge, we adapted two existing systems:…”
Get full text