Search Results - "Wilson, Daisy"
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Inflammation and neutrophil immunosenescence in health and disease: Targeted treatments to improve clinical outcomes in the elderly
Published in Experimental gerontology (01-05-2018)“…Despite increasing longevity, many old people are not in good health. There has been an increase in the prevalence of age-associated multi-morbidity (two or…”
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Frailty and Sarcopenia: The potential role of an aged immune system
Published in Ageing research reviews (01-07-2017)“…Highlights • Clinical and pathophysiological relationships in sarcopenia and frailty. • Inflammaging in sarcopenia and frailty. • Physical inactivity in…”
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Innate Immune Cells in Liver Inflammation
Published in Mediators of Inflammation (01-01-2012)“…Innate immune system is the first line of defence against invading pathogens that is critical for the overall survival of the host. Human liver is…”
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Screening Carbon Nano Materials for Preventing Amyloid Protein Aggregation by Adopting a Facile Method
Published in Cell biochemistry and biophysics (01-06-2024)“…The soluble-to-toxic transformation of intrinsically disordered amyloidogenic proteins such as amyloid beta (Aβ), α-synuclein, mutant Huntingtin Protein (mHTT)…”
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Bilateral Anterior Thigh Thickness: A New Diagnostic Tool for the Identification of Low Muscle Mass?
Published in Journal of the American Medical Directors Association (01-10-2019)“…To develop an ultrasonographic scanning protocol that included an assessment of muscle size [the proposed Bilateral Anterior Thigh Thickness (BATT)] and…”
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Nutrition and Frailty: Opportunities for Prevention and Treatment
Published in Nutrients (01-07-2021)“…Frailty is a syndrome of growing importance given the global ageing population. While frailty is a multifactorial process, poor nutritional status is…”
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The Role of Fullerenes in Neurodegenerative Disorders
Published in Journal of nanotheranostics (01-01-2024)“…The use of carbon nanomaterials including fullerenes, carbon nanotubes, carbon nano-onions, carbon dots and carbon quantum dots for environmental applications…”
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Ultrasound quadriceps muscle thickness is variably associated with frailty in haemodialysis recipients
Published in BMC nephrology (18-01-2023)“…Ultrasonographic quantitation of quadriceps muscle mass is increasingly used for assessment of sarcopenia, but its relationship with frailty in haemodialysis…”
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Age-Related Anabolic Resistance of Myofibrillar Protein Synthesis Is Exacerbated in Obese Inactive Individuals
Published in The journal of clinical endocrinology and metabolism (01-09-2017)“…Abstract Context A diminished muscle anabolic response to protein nutrition may underpin age-associated muscle loss. Objective To determine how chronological…”
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The challenges of muscle biopsy in a community based geriatric population
Published in BMC research notes (26-11-2018)“…To describe the difficulties of obtaining muscle samples using a Bergstrom needle technique in a frail older adult population. The data were obtained from a…”
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Gender Disparity in Expression of Sarcopenia in Haemodialysis Recipients: Analysis from the FITNESS Cohort
Published in International journal of nephrology (17-06-2023)“…Background. There has been little exploration of the interplay between sarcopenia and frailty in haemodialysis, particularly regarding gender difference. We…”
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Using Social Media and Web-Based Networking in Collaborative Research: Protocol for the Geriatric Medicine Research Collaborative
Published in JMIR research protocols (01-10-2018)“…Traditional pathways to promote research collaboration typically take years to expand beyond individual institutions. Social media and online networking…”
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Development of a UK core dataset for geriatric medicine research: a position statement and results from a Delphi consensus process
Published in BMC geriatrics (23-03-2023)“…There is lack of standardisation in assessment tools used in geriatric medicine research, which makes pooling of data and cross-study comparisons difficult. We…”
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Effect of position and exercise on measurement of muscle quantity and quality: towards a standardised pragmatic protocol for clinical practice
Published in BMC sports science, medicine & rehabilitation (07-01-2021)“…Ultrasonography is an emerging non-invasive bedside tool for muscle quantity/quality assessment; Bioelectrical Impedance Analysis (BIA) is an alternative…”
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Carbon nanotubes as neuroprotective agents
Published in Exploration of neuroprotective therapy (27-02-2024)“…Carbon nanotubes, an emerging class of carbon nanomaterials, possess tremendous potential for application in biotechnology and biomedicine particularly in…”
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COVID-19 and Acute Sarcopenia
Published in Aging and disease (01-12-2020)“…The COVID-19 pandemic has had a devastating global impact, with older adults being most at risk of death from the disease. However, acute sarcopenia occurs in…”
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Predicting outcome in older hospital patients with delirium: a systematic literature review
Published in International journal of geriatric psychiatry (01-04-2016)“…Objective Delirium is a serious neuropsychiatric syndrome common in older hospitalised adults. It is associated with poor outcomes, however not all people with…”
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Repurposing digoxin for geroprotection in patients with frailty and multimorbidity
Published in Ageing research reviews (01-04-2023)“…The geroscience hypothesis proposes biological hallmarks of ageing are modifiable. Increasing evidence supports targeting these hallmarks with therapeutics…”
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Age and frailty are independently associated with increased COVID-19 mortality and increased care needs in survivors: results of an international multi-centre study
Published in Age and ageing (05-05-2021)“…Abstract Introduction Increased mortality has been demonstrated in older adults with coronavirus disease 2019 (COVID-19), but the effect of frailty has been…”
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Frailty Is Associated With Neutrophil Dysfunction Which Is Correctable With Phosphoinositol-3-Kinase Inhibitors
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-12-2020)“…Abstract Neutrophil dysfunction has been described with age, appears exaggerated in infection, with altered phosphoinositol signaling a potential mechanism…”
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