Search Results - "Wilson, Bridget S."

ErbB1 dimerization is promoted by domain co-confinement and stabilized by ligand binding by Lidke, Diane S, Low-Nam, Shalini T, Lidke, Keith A, Cutler, Patrick J, Roovers, Rob C, van Bergen en Henegouwen, Paul M P, Wilson, Bridget S

“…Dimerization, ligand-binding and co-confinement are all expected to contribute to erbB1 signaling, but the level of their contribution has not yet been fully…”
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erbB3 Is an Active Tyrosine Kinase Capable of Homo- and Heterointeractions by Steinkamp, Mara P., Low-Nam, Shalini T., Yang, Shujie, Lidke, Keith A., Lidke, Diane S., Wilson, Bridget S.

“…Classifications Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Enhanced dimerization drives ligand-independent activity of mutant epidermal growth factor receptor in lung cancer by Valley, Christopher C, Arndt-Jovin, Donna J, Karedla, Narain, Steinkamp, Mara P, Chizhik, Alexey I, Hlavacek, William S, Wilson, Bridget S, Lidke, Keith A, Lidke, Diane S

“…Mutations within the epidermal growth factor receptor (EGFR/erbB1/Her1) are often associated with tumorigenesis. In particular, a number of EGFR mutants that…”
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Plasma Membrane-Associated Proteins Are Clustered into Islands Attached to the Cytoskeleton by Lillemeier, Björn F., Pfeiffer, Janet R., Surviladze, Zurab, Wilson, Bridget S., Davis, Mark M.

“…Although much evidence suggests that the plasma membrane of eukaryotic cells is not homogenous, the precise architecture of this important structure has not…”
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Editorial: Structure, Isotypes, Targets, and Post-translational Modifications of Immunoglobulins and Their Role in Infection, Inflammation and Autoimmunity by Harb, Jean, Wilson, Bridget S, Hermouet, Sylvie

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Mpl Traffics to the Cell Surface Through Conventional and Unconventional Routes by Cleyrat, Cédric, Darehshouri, Anza, Steinkamp, Mara P., Vilaine, Mathias, Boassa, Daniela, Ellisman, Mark H., Hermouet, Sylvie, Wilson, Bridget S.

“…Myeloproliferative neoplasms (MPNs) are often characterized by JAK2 or calreticulin (CALR) mutations, indicating aberrant trafficking in pathogenesis. This…”
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Membrane-Mediated Regulation of the Intrinsically Disordered CD3ϵ Cytoplasmic Tail of the TCR by López, Cesar A., Sethi, Anurag, Goldstein, Byron, Wilson, Bridget S., Gnanakaran, S.

“…The regulation of T-cell-mediated immune responses depends on the phosphorylation of immunoreceptor tyrosine-based activation motifs (ITAMs) on T-cell…”
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Timescale Separation of Positive and Negative Signaling Creates History-Dependent Responses to IgE Receptor Stimulation by Harmon, Brooke, Chylek, Lily A., Liu, Yanli, Mitra, Eshan D., Mahajan, Avanika, Saada, Edwin A., Schudel, Benjamin R., Holowka, David A., Baird, Barbara A., Wilson, Bridget S., Hlavacek, William S., Singh, Anup K.

“…The high-affinity receptor for IgE expressed on the surface of mast cells and basophils interacts with antigens, via bound IgE antibody, and triggers secretion…”
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High Incidence of ErbB3, ErbB4, and MET Expression in Ovarian Cancer by Davies, Suzy, Holmes, Anna, Lomo, Lesley, Steinkamp, Mara P, Kang, Huining, Muller, Carolyn Y, Wilson, Bridget S

“…Ovarian cancer is the leading cause of death from gynecologic cancers in the United States. Failure may be due to variable expression and/or complex…”
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Water-Soluble Germanium(0) Nanocrystals: Cell Recognition and Near-Infrared Photothermal Conversion Properties by Lambert, Timothy N., Andrews, Nicholas L., Gerung, Henry, Boyle, Timothy J., Oliver, Janet M., Wilson, Bridget S., Han, Sang M.

“…Surfactant‐passivated germanium nanocrystals (Ge(0) NCs) 3–5 nm in diameter were synthesized and encapsulated with functionalized phospholipids to yield…”
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EGFR transactivates RON to drive oncogenic crosstalk by Franco Nitta, Carolina, Green, Ellen W, Jhamba, Elton D, Keth, Justine M, Ortiz-Caraveo, Iraís, Grattan, Rachel M, Schodt, David J, Gibson, Aubrey C, Rajput, Ashwani, Lidke, Keith A, Wilson, Bridget S, Steinkamp, Mara P, Lidke, Diane S

“…Crosstalk between different receptor tyrosine kinases (RTKs) is thought to drive oncogenic signaling and allow therapeutic escape. EGFR and RON are two such…”
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Orchestration of ErbB3 signaling through heterointeractions and homointeractions by McCabe Pryor, Meghan, Steinkamp, Mara P, Halasz, Adam M, Chen, Ye, Yang, Shujie, Smith, Marilyn S, Zahoransky-Kohalmi, Gergely, Swift, Mark, Xu, Xiao-Ping, Hanein, Dorit, Volkmann, Niels, Lidke, Diane S, Edwards, Jeremy S, Wilson, Bridget S

“…Members of the ErbB family of receptor tyrosine kinases are capable of both homointeractions and heterointeractions. Because each receptor has a unique set of…”
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Dynamic Transition States of ErbB1 Phosphorylation Predicted by Spatial Stochastic Modeling by Pryor, Meghan McCabe, Low-Nam, Shalini T., Halász, Ádám M., Lidke, Diane S., Wilson, Bridget S., Edwards, Jeremy S.

“…ErbB1 overexpression is strongly linked to carcinogenesis, motivating better understanding of erbB1 dimerization and activation. Recent…”
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Subcellular distribution of Lck during CD4 T-cell maturation in the thymic medulla regulates the T-cell activation threshold by Stephen, Tom Li, Wilson, Bridget S., Laufer, Terri M.

“…Mature peripheral T cells respond to foreign but not to self-antigens. During development in the thymus, deletion of high-affinity self-reactive immature…”
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Single-cell measurements of IgE-mediated FcεRI signaling using an integrated microfluidic platform by Liu, Yanli, Barua, Dipak, Liu, Peng, Wilson, Bridget S, Oliver, Janet M, Hlavacek, William S, Singh, Anup K

“…Heterogeneity in responses of cells to a stimulus, such as a pathogen or allergen, can potentially play an important role in deciding the fate of the…”
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Mathematical Simulation of Membrane Protein Clustering for Efficient Signal Transduction by Radhakrishnan, Krishnan, Halász, Ádám, McCabe, Meghan M., Edwards, Jeremy S., Wilson, Bridget S.

“…Initiation and propagation of cell signaling depend on productive interactions among signaling proteins at the plasma membrane. These diffusion-limited…”
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The architectural relationship of components controlling mast cell endocytosis by Cleyrat, Cédric, Darehshouri, Anza, Anderson, Karen L, Page, Christopher, Lidke, Diane S, Volkmann, Niels, Hanein, Dorit, Wilson, Bridget S

“…Eukaryotic cells use multiple routes for receptor internalization. Here, we examine the topographical relationships of clathrin-dependent and…”
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Markers for detergent-resistant lipid rafts occupy distinct and dynamic domains in native membranes by Wilson, Bridget S, Steinberg, Stanly L, Liederman, Karin, Pfeiffer, Janet R, Surviladze, Zurab, Zhang, Jun, Samelson, Lawrence E, Yang, Li-Hong, Kotula, Paul G, Oliver, Janet M

“…Lipid rafts isolated by detergent extraction and sucrose gradient fractionation from mast cells are enriched for the glycosylphosphatidylinositol-linked…”
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Coupled stochastic spatial and non-spatial simulations of ErbB1 signaling pathways demonstrate the importance of spatial organization in signal transduction by Costa, Michelle N, Radhakrishnan, Krishnan, Wilson, Bridget S, Vlachos, Dionisios G, Edwards, Jeremy S

“…The ErbB family of receptors activates intracellular signaling pathways that control cellular proliferation, growth, differentiation and apoptosis. Given these…”
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Survival of Staphylococcus aureus Inside Neutrophils Contributes to Infection by Gresham, Hattie D, Lowrance, Jon H, Caver, Tony E, Wilson, Bridget S, Cheung, Ambrose L, Lindberg, Frederik P

“…Neutrophils have long been regarded as essential for host defense against Staphylococcus aureus infection. However, survival of the pathogen inside various…”
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