Search Results - "Wilson, BC"

Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, protects dopaminergic neurons from neurotoxin‐induced damage by Chen, SH, Wu, HM, Ossola, B, Schendzielorz, N, Wilson, BC, Chu, CH, Chen, SL, Wang, Q, Zhang, D, Qian, L, Li, X, Hong, JS, Lu, RB

“…BACKGROUND AND PURPOSE Prevention or disease‐modifying therapies are critical for the treatment of neurodegenerative disorders such as Alzheimer's disease,…”
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Volume CT with a flat-panel detector on a mobile, isocentric C-arm: Pre-clinical investigation in guidance of minimally invasive surgery by Siewerdsen, J. H., Moseley, D. J., Burch, S., Bisland, S. K., Bogaards, A., Wilson, B. C., Jaffray, D. A.

“…A mobile isocentric C-arm (Siemens PowerMobil) has been modified in our laboratory to include a large area flat-panel detector (in place of the x-ray image…”
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Direct Near-infrared Luminescence Detection of Singlet Oxygen Generated by Photodynamic Therapy in Cells In Vitro and Tissues In Vivo by Niedre, Mark, Patterson, Michael S., Wilson, Brian C.

“…Singlet oxygen (1O2) is believed to be the major cytotoxic agent involved in photodynamic therapy (PDT). Measurement of 1O2 near-infrared (NIR) luminescence at…”
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Simultaneous Two-photon Excitation of Photofrin in Relation to Photodynamic Therapy by Karotki, Aliaksandr, Khurana, Mamta, Lepock, James R., Wilson, Brian C.

“…Photodynamic therapy (PDT), the use of light-activated drugs (photosensitizers), is an emerging treatment modality for tumors as well as various nononcologic…”
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The Microenvironment Effect on the Generation of Reactive Oxygen Species by Pd−Bacteriopheophorbide by Vakrat-Haglili, Yahel, Weiner, Lev, Brumfeld, Vlad, Brandis, Alexander, Salomon, Yoram, Mcllroy, Brian, Wilson, Brian C, Pawlak, Anna, Rozanowska, Malgorzata, Sarna, Tadeusz, Scherz, Avigdor

“…Generation of reactive oxygen species (ROS) is the hallmark of important biological processes and photodynamic therapy (PDT), where ROS production results from…”
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In vitro tests of the validity of singlet oxygen luminescence measurements as a dose metric in photodynamic therapy by NIEDRE, Mark J, SECORD, Andrea J, PATTERSON, Michael S, WILSON, Brian C

“…Singlet oxygen ((1)O(2)) is widely believed to be the major cytotoxic agent involved in photodynamic therapy (PDT). We showed recently that measurement of the…”
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Abstract P4-03-05: Wide-field optical coherence tomography (WF-OCT) for near real-time, point-of-care assessment of margin status in breast-conserving surgery specimens: Results of a feasibility study at a high-volume single-centre by Valic, MS, Leong, WL, Done, SJ, Wilson, BC, Kulkarni, S, McCready, DR, Niu, CJ, Atachia, Y, Munro, EA, Rempel, D

“…Abstract Wide-Field Optical Coherence Tomography (WF-OCT) is a non-destructive, non-contact light imaging modality capable of label-free visualization of the…”
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Abstract P4-03-04: The potential use of Optical Coherence Tomography for intraoperative breast tumour margin width estimation by Wilson, BC, Akens, MK, Niu, CJ

“…Abstract Total mastectomy and lumpectomy with radiation have been shown to have equivalent patient outcomes, which has likely contributed to the more…”
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Diagnostic potential of near-infrared Raman spectroscopy in the colon: Differentiating adenomatous from hyperplastic polyps by Molckovsky, Andrea, Song, Louis-Michel Wong Kee, Shim, Martin G., Marcon, Norman E., Wilson, Brian C.

“…Background: Near-infrared Raman spectroscopy is a promising optical technique for GI tissue diagnosis. This study assessed the diagnostic potential of…”
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Protease-Triggered Photosensitizing Beacon Based on Singlet Oxygen Quenching and Activation by Chen, Juan, Stefflova, Klara, Niedre, Mark J, Wilson, Brian C, Chance, Britton, Glickson, Jerry D, Zheng, Gang

“…We report a new concept for type-II photosensitization, based on incorporating the photosensitizer (PS) and a singlet-oxygen (1O2) quenching/scavenging…”
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Singlet oxygen luminescence as an in vivo photodynamic therapy dose metric: validation in normal mouse skin with topical amino-levulinic acid by NIEDRE, M. J, YU, C. S, PATTERSON, M. S, WILSON, B. C

“…Although singlet oxygen ((1)O(2)) has long been proposed as the primary reactive oxygen species in photodynamic therapy (PDT), it has only recently been…”
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High speed, wide velocity dynamic range Doppler optical coherence tomography (Part I): System design, signal processing, and performance by Yang, Victor, Gordon, Maggie, Qi, Bing, Pekar, Julius, Lo, Stuart, Seng-Yue, Emily, Mok, Alvin, Wilson, Brian, Vitkin, I

“…Improvements in real-time Doppler optical coherence tomography (DOCT), acquiring up to 32 frames per second at 250 x 512 pixels per image, are reported using…”
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Photodynamic therapy for urological malignancies: past to current approaches by Pinthus, Jehonathan H, Bogaards, Arjen, Weersink, Robert, Wilson, Brian C, Trachtenberg, John

“…Modern PDT for urological tumors is a potentially selective approach in which in situ photosensitization by a nontoxic drug, locally activated by light,…”
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Metronomic Photodynamic Therapy as a New Paradigm for Photodynamic Therapy: Rationale and Preclinical Evaluation of Technical Feasibility for Treating Malignant Brain Tumors by Bisland, Stuart K., Lilge, Lothar, Lin, Annie, Rusnov, Robert, Wilson, Brian C.

“…The concept of metronomic photodynamic therapy (mPDT) is presented, in which both the photosensitizer and light are delivered continuously at low rates for…”
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Techniques for delivery and monitoring of TOOKAD (WST09)-mediated photodynamic therapy of the prostate: Clinical experience and practicalities by Weersink, Robert A., Bogaards, Arjen, Gertner, Mark, Davidson, Sean R.H., Zhang, Kai, Netchev, George, Trachtenberg, John, Wilson, Brian C.

“…Photodynamic therapy of solid organs requires sufficient PDT dose throughout the target tissue while minimizing the dose to proximal normal structures. This…”
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Molecular Fluorescence Excitation–Emission Matrices Relevant to Tissue Spectroscopy by DaCosta, Ralph S., Andersson, Helene, Wilson, Brian C.

“…In vivo and ex vivo studies of fluorescence from endogenous and exogenous molecules in tissues and cells are common for applications such as detection or…”
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In vivo Near-infrared Raman Spectroscopy: Demonstration of Feasibility During Clinical Gastrointestinal Endoscopy by Shim, Martin G., Wong Kee Song, Louis-Michel, Marcon, Norman E., Wilson, Brian C.

“…Raman spectroscopy (RS) has potential for disease classification within the gastrointestinal tract (GI). A near-infrared (NIR) fiber-optic RS system has been…”
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Optical techniques for the endoscopic detection of dysplastic colonic lesions by DaCosta, Ralph S, Wilson, Brian C, Marcon, Norman E

“…PURPOSE OF REVIEWWithin the past decade, advances in biomedical optics have been applied to overcome sensitivity and specificity limitations in conventional…”
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Pre-clinical in vitro and in vivo studies to examine the potential use of photodynamic therapy in the treatment of osteomyelitis by Bisland, Stuart K, Chien, Claudia, Wilson, Brian C, Burch, Shane

“…Osteomyelitis can lead to severe morbidity and even death resulting from an acute or chronic inflammation of the bone and contiguous structures due to fungal…”
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Interstitial Doppler optical coherence tomography by Yang, Victor X D, Mao, You X, Munce, Nigel, Standish, Beau, Kucharczyk, Walter, Marcon, Norman E, Wilson, Brian C, Vitkin, I Alex

“…Doppler optical coherence tomography (OCT) can image tissue structure and blood flow at micrometer-scale resolution but has limited imaging depth. We report a…”
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