Search Results - "Wilson, Andrew F"

FANCD2 is required for the repression of germline transposable elements by Nie, Yan, Wilson, Andrew F, DeFalco, Tony, Meetei, Amom Ruhikanta, Namekawa, Satoshi H, Pang, Qishen

“…The Fanconi anemia (FA) DNA damage response (DDR) pathway regulate important cellular processes such as DNA replication, cell cycle control and DNA damage…”
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Persistent DNA damage and oncogenic stress-induced Trem1 promotes leukemia in mice by Li, Xue, Chatla, Srinivas, Wilson, Andrew F, Wu, Limei, Atale, Neha, Du, Wei

“…The immune receptor TREM1 (Triggering receptor expressed on myeloid cells 1) is a master regulator of inflammatory response. Compelling evidence suggests…”
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SCO2 Mediates Oxidative Stress‐Induced Glycolysis to Oxidative Phosphorylation Switch in Hematopoietic Stem Cells by Du, Wei, Amarachintha, Surya, Wilson, Andrew F., Pang, Qishen

“…Fanconi anemia (FA) is an inherited bone marrow (BM) failure syndrome, presumably resulting from defects in hematopoietic stem cells (HSCs). Normal HSCs depend…”
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Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function by Zhang, Tingting, Du, Wei, Wilson, Andrew F., Namekawa, Satoshi H., Andreassen, Paul R., Meetei, Amom Ruhikanta, Pang, Qishen

“…Fancd2 is a component of the Fanconi anemia (FA) DNA repair pathway, which is frequently found defective in human cancers. The full repertoire of Fancd2…”
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Cell-Cycle-Specific Function of p53 in Fanconi Anemia Hematopoietic Stem and Progenitor Cell Proliferation by Li, Xiaoli, Wilson, Andrew F., Du, Wei, Pang, Qishen

“…Overactive p53 has been proposed as an important pathophysiological factor for bone marrow failure syndromes, including Fanconi anemia (FA). Here, we report a…”
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Fancd2-deficient hematopoietic stem and progenitor cells depend on augmented mitochondrial translation for survival and proliferation by Chatla, Srinivas, Du, Wei, Wilson, Andrew F., Meetei, Amom Ruhikanta, Pang, Qishen

“…Members of the Fanconi anemia (FA) protein family are involved in multiple cellular processes including response to DNA damage and oxidative stress. Here we…”
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The non-homologous end-joining activity is required for Fanconi anemia fetal HSC maintenance by Nie, Yan, Li, Yibo, Li, Xiaoli, Wilson, Andrew F, Pang, Qishen

“…Recent studies have shown that deficiency in the Fanconi anemia (FA) DNA repair pathway enhances the error-prone non-homologous end-joining (NHEJ) repair,…”
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A small molecule p53 activator attenuates Fanconi anemia leukemic stem cell proliferation by Du, Wei, Li, Xiaoli, Wilson, Andrew F, Pang, Qishen

“…Although p53 mutations are common in solid tumors, such mutations are found at a lower frequency in hematologic malignancies. In the genetic disorder Fanconi…”
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LepR+ niche cell–derived AREG compromises hematopoietic stem cell maintenance under conditions of DNA repair deficiency and aging by Wu, Limei, Lin, Qiqi, Chatla, Srinivas, Amarachintha, Surya, Wilson, Andrew F., Atale, Neha, Gao, Zhenxia J., Joseph, Jonathan, Wolff, Emily V., Du, Wei

“…•Persistent DNA damage induces AREG expression in BM LepR+ cells deficient of the Brca2 gene.•Overproduced AREG activates the PI3K/AKT/mTOR pathway, promotes…”
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Persistent response of Fanconi anemia haematopoietic stem and progenitor cells to oxidative stress by Li, Yibo, Amarachintha, Surya, Wilson, Andrew F, Li, Xue, Du, Wei

“…Oxidative stress is considered as an important pathogenic factor in many human diseases including Fanconi anemia (FA), an inherited bone marrow failure…”
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Hyper-active non-homologous end joining selects for synthetic lethality resistant and pathological Fanconi anemia hematopoietic stem and progenitor cells by Du, Wei, Amarachintha, Surya, Wilson, Andrew F., Pang, Qishen

“…The prominent role of Fanconi anemia (FA) proteins involves homologous recombination (HR) repair. Poly[ADP-ribose] polymerase1 (PARP1) functions in multiple…”
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Inactivation of the NHEJ Activity of DNA-PKcs Prevents Fanconi Anemia Pre-Leukemic HSC Expansion by Chatla, Srinivas, Wilson, Andrew F, Pang, Qishen

“…Fanconi anemia (FA) is a genetic disorder characterized by bone marrow failure and high risk of cancer particularly leukemia. Here we show that inactivation of…”
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whitegenocide, the Alt-right and Conspiracy Theory: How Secrecy and Suspicion Contributed to the Mainstreaming of Hate by Wilson, Andrew F.

“…This article considers the relationship between “hashtag activism” as it is currently being used by the alt-right and the tendency to draw on conspiracy theory…”
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Loss of Faap20 Causes Hematopoietic Stem and Progenitor Cell Depletion in Mice Under Genotoxic Stress by Zhang, Tingting, Wilson, Andrew F., Mahmood Ali, Abdullah, Namekawa, Satoshi H., Andreassen, Paul R., Ruhikanta Meetei, Amom, Pang, Qishen

“…20‐kDa FANCA‐associated protein (FAAP20) is a recently identified protein that associates with the Fanconi anemia (FA) core complex component, FANCA. FAAP20…”
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SCO2 mediates oxidative stress-induced glycolysis to OXPHOS switch in hematopoietic stem cells by Du, Wei, Amarachintha, Surya, Wilson, Andrew F., Pang, Qishen

“…Fanconi anemia (FA) is an inherited bone marrow (BM) failure syndrome, presumably resulting from defects in hematopoietic stem cells (HSCs). Normal HSCs depend…”
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Roberto Sorrentino [In Memoriam] by Vander Vorst, Andre, Heinrich, Wolfgang, Wilson, Andrew F., Hauser, Jerry

“…Recounts the career and contributions of Roberto Sorrentino…”
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Some observations on the development of the European Microwave Association by Wilson, Andrew F.

“…The Honorary Secretary of the European Microwave Association was appointed in 1988 and is still in position. This paper describes the evolution of the concepts…”
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Persistent response of Fanconi anemia haematopoietic stem and progenitor cells to oxidative stress by Li, Yibo, Amarachintha, Surya, Wilson, Andrew F., Li, Xue, Du, Wei

“…Oxidative stress is considered as an important pathogenic factor in many human diseases including Fanconi anemia (FA), an inherited bone marrow failure…”
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