Search Results - "Wilschut, J."
-
1
Membrane-free culture and real-time barrier integrity assessment of perfused intestinal epithelium tubes
Published in Nature communications (15-08-2017)“…In vitro models that better reflect in vivo epithelial barrier (patho-)physiology are urgently required to predict adverse drug effects. Here we introduce…”
Get full text
Journal Article -
2
A perfused human blood-brain barrier on-a-chip for high-throughput assessment of barrier function and antibody transport
Published in Fluids and barriers of the CNS (31-08-2018)“…Receptor-mediated transcytosis is one of the major routes for drug delivery of large molecules into the brain. The aim of this study was to develop a novel…”
Get full text
Journal Article -
3
High-throughput compound evaluation on 3D networks of neurons and glia in a microfluidic platform
Published in Scientific reports (09-12-2016)“…With great advances in the field of in vitro brain modelling, the challenge is now to implement these technologies for development and evaluation of new drug…”
Get full text
Journal Article -
4
Screening for colorectal cancer: random comparison of guaiac and immunochemical faecal occult blood testing at different cut-off levels
Published in British journal of cancer (07-04-2009)“…Immunochemical faecal occult blood testing (FIT) provides quantitative test results, which allows optimisation of the cut-off value for follow-up colonoscopy…”
Get full text
Journal Article -
5
Randomized clinical trial of selective decontamination of the digestive tract in elective colorectal cancer surgery (SELECT trial)
Published in British journal of surgery (01-03-2019)“…Background Infectious complications and anastomotic leakage affect approximately 30 per cent of patients after colorectal cancer surgery. The aim of this…”
Get full text
Journal Article -
6
Human Satellite Cell Transplantation and Regeneration from Diverse Skeletal Muscles
Published in Stem cell reports (08-09-2015)“…Identification of human satellite cells that fulfill muscle stem cell criteria is an unmet need in regenerative medicine. This hurdle limits understanding how…”
Get full text
Journal Article -
7
Immediate versus staged revascularisation of non-culprit arteries in patients with acute coronary syndrome: a systematic review and meta-analysis
Published in Netherlands heart journal (01-10-2022)“…Although there is robust evidence that revascularisation of non-culprit vessels should be pursued in patients presenting with an acute coronary syndrome (ACS)…”
Get full text
Journal Article -
8
Development of a Virosomal RSV Vaccine Containing 3D-PHAD® Adjuvant: Formulation, Composition, and Long-Term Stability
Published in Pharmaceutical research (01-09-2018)“…Purpose Characterization of virosomes, in late stage preclinical development as vaccines for Respiratory Syncytial Virus (RSV), with a membrane-incorporated…”
Get full text
Journal Article -
9
Development of Stable Influenza Vaccine Powder Formulations: Challenges and Possibilities
Published in Pharmaceutical research (01-06-2008)“…Influenza vaccination represents the cornerstone of influenza prevention. However, today all influenza vaccines are formulated as liquids that are unstable at…”
Get full text
Journal Article -
10
Wegener's granulomatosis patients show an adequate antibody response to influenza vaccination
Published in Annals of the rheumatic diseases (01-06-2009)“…Wegener's granulomatosis (WG) is a systemic vasculitis characterised by relapsing and remitting disease activity. Immunosuppressive drugs are used to control…”
Get more information
Journal Article -
11
Cost–effectiveness of the prophylactic HPV vaccine: An application to the Netherlands taking non-cervical cancers and cross-protection into account
Published in Vaccine (20-08-2013)“…Highlights • We examine the cost–effectiveness of the bivalent HPV-vaccine. • Cross-protection and protection against non-cervical cancers are taken into…”
Get full text
Journal Article -
12
Influenza vaccination in healthcare workers; comparison of side effects and preferred route of administration of intradermal versus intramuscular administration
Published in Vaccine (13-03-2017)“…Highlights • The side effects of intradermal and intramuscular influenza vaccine are different. • Health care workers do not prefer one type of vaccine to the…”
Get full text
Journal Article -
13
Cost-effectiveness of potential infant vaccination against respiratory syncytial virus infection in The Netherlands
Published in Vaccine (29-06-2012)“…Highlights ► In the Netherlands, there is potential for RSV-vaccination of children to be cost-effective. ► Clinical research is needed on dose schedule, time…”
Get full text
Journal Article -
14
Isolation and characterization of porcine adult muscle-derived progenitor cells
Published in Journal of cellular biochemistry (01-12-2008)“…Here, we report the isolation of progenitor cells from pig skeletal muscle tissue fragments. Muscle progenitor cells were stimulated to migrate from…”
Get full text
Journal Article -
15
Which factors are important in adults’ uptake of a (pre)pandemic influenza vaccine?
Published in Vaccine (10-12-2009)“…Abstract Since 2008, (pre)pandemic vaccines against H5N1 influenza have been available and pandemic vaccines against new influenza H1N1 are currently produced…”
Get full text
Journal Article -
16
Safety and efficacy of influenza vaccination in systemic lupus erythematosus patients with quiescent disease
Published in Annals of the rheumatic diseases (01-07-2006)“…Objective: to assess the safety and efficacy of influenza vaccination in patients with systemic lupus erythematosus (SLE), and to evaluate the influence of…”
Get full text
Journal Article -
17
Concise Review: Stem Cell Therapy for Muscular Dystrophies
Published in Stem cells translational medicine (01-11-2012)“…Muscular dystrophy comprises a group of genetic diseases that cause progressive weakness and degeneration of skeletal muscle resulting from defective proteins…”
Get full text
Journal Article -
18
Dynamic modelling approaches for the analysis of the cost-effectiveness of seasonal influenza control
Published in Expert review of vaccines (01-01-2017)Get full text
Journal Article -
19
An update on the use of anticoagulant therapy in ST-segment elevation myocardial infarction
Published in Expert opinion on pharmacotherapy (02-09-2018)“…Together with antiplatelet therapy, anticoagulants are vital to improve outcomes in patients presenting with ST-segment elevation myocardial infarction…”
Get more information
Journal Article -
20
Advance notification letters increase adherence in colorectal cancer screening: A population-based randomized trial
Published in Preventive medicine (01-06-2011)“…The population benefit of screening depends not only on the effectiveness of the test, but also on adherence, which, for colorectal cancer (CRC) screening…”
Get full text
Journal Article