Search Results - "Wilmot, R"

Establishing pragmatic estimated GFR thresholds to guide metformin prescribing by Shaw, J. S., Wilmot, R. L., Kilpatrick, E. S.

“…Aims  Renal impairment is a contraindication to metformin treatment because of the perceived increased risk of lactic acidosis. Current guidelines define renal…”
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Measuring Friedreich ataxia : Complementary features of examination and performance measures by LYNCH, D. R, FARMER, J. M, TSOU, A. Y, PERLMAN, S, SUBRAMONY, S. H, GOMEZ, C. M, ASHIZAWA, T, WILMOT, G. R, WILSON, R. B, BALCER, L. J

“…To examine the potential validity of performance measures and examination-based scales in Friedreich ataxia (FA) by examining their correlation with disease…”
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Analysis of Echocardiograms in a Large Heterogeneous Cohort of Patients With Friedreich Ataxia by Regner, Sean R., BS, Lagedrost, Sarah J., BA, Plappert, Ted, CVT, Paulsen, Erin K., BA, Friedman, Lisa S., BSN, Snyder, Madeline L., BA, Perlman, Susan L., MD, Mathews, Katherine D., MD, Wilmot, George R., MD, PhD, Schadt, Kimberly A., MSN, CRNP, Sutton, Martin St. John, MBBS, Lynch, David R., MD, PhD

“…Although Friedreich ataxia (FA) is associated with cardiomyopathy, the severity and evolution of cardiac disease is poorly understood. To identify factors…”
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Managing human-habituated bears to enhance survival, habitat effectiveness, and public viewing by Gunther, Kerry A, Wilmot, Katharine R, Cain, Steven L, Wyman, Travis, Reinertson, Eric G, Bramblett, Amanda M

“…The negative impacts on bears (Ursus spp.) from human activities associated with roads and developments are well documented. These impacts include displacement…”
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Emerging therapies in Friedreich's ataxia by Aranca, Tanya V, Jones, Tracy M, Shaw, Jessica D, Staffetti, Joseph S, Ashizawa, Tetsuo, Kuo, Sheng-Han, Fogel, Brent L, Wilmot, George R, Perlman, Susan L, Onyike, Chiadi U, Ying, Sarah H, Zesiewicz, Theresa A

“…Friedreich's ataxia (FRDA) is an inherited, progressive neurodegenerative disease that typically affects teenagers and young adults. Therapeutic strategies and…”
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Experimental and computational comparison of freeze–thaw-induced pressure generation in red and sugar maple by Zarrinderakht, Maryam, Konrad, Isabell, Wilmot, Timothy R, Perkins, Timothy D, van den Berg, Abby K, Stockie, John M

“…Abstract Sap exudation is the process whereby trees such as sugar (Acer saccharum Marsh.) and red maple (Acer rubrum L.) generate unusually high positive stem…”
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Mortality in Friedreich Ataxia by Tsou, Amy Y, Paulsen, Erin K, Lagedrost, Sarah J, Perlman, Susan L, Mathews, Katherine D, Wilmot, George R, Ravina, Bernard, Koeppen, Arnulf H, Lynch, David R

“…Abstract Background Although cardiac dysfunction is widely accepted as the most common cause of mortality in Friedreich ataxia (FRDA), no studies have…”
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Evidence for density‐dependent effects on body composition of a large omnivore in a changing Greater Yellowstone Ecosystem by Corradini, Andrea, Haroldson, Mark A., Cagnacci, Francesca, Costello, Cecily M., Bjornlie, Daniel D., Thompson, Daniel J., Nicholson, Jeremy M., Gunther, Kerry A., Wilmot, Katharine R., Manen, Frank T.

“…Understanding the density‐dependent processes that drive population demography in a changing world is critical in ecology, yet measuring performance–density…”
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Mitochondrial DNA variation and genetic population structure of chum salmon Oncorhynchus keta around the Pacific Rim by Yoon, M., Sato, S., Seeb, J. E., Brykov, V., Seeb, L. W., Varnavskaya, N. V., Wilmot, R. L., Jin, D. H., Urawa, S., Urano, A., Abe, S.

“…A survey of mtDNA variation among populations of chum salmon Oncorhynchus keta around the Pacific Rim revealed four large population groups: Rim of the Sea of…”
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Safety, pharmacodynamics, and potential benefit of omaveloxolone in Friedreich ataxia by Lynch, David R., Farmer, Jennifer, Hauser, Lauren, Blair, Ian A., Wang, Qing Qing, Mesaros, Clementina, Snyder, Nathaniel, Boesch, Sylvia, Chin, Melanie, Delatycki, Martin B., Giunti, Paola, Goldsberry, Angela, Hoyle, Chad, McBride, Michael G., Nachbauer, Wolfgang, O'Grady, Megan, Perlman, Susan, Subramony, S. H., Wilmot, George R., Zesiewicz, Theresa, Meyer, Colin

“…Objective Previous studies have demonstrated that suppression of Nrf2 in Friedreich ataxia tissues contributes to excess oxidative stress, mitochondrial…”
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SARA captures disparate progression and responsiveness in spinocerebellar ataxias by Petit, Emilien, Schmitz-Hübsch, Tanja, Coarelli, Giulia, Jacobi, Heike, Heinzmann, Anna, Figueroa, Karla P., Perlman, Susan L., Gomez, Christopher M., Wilmot, George R., Schmahmann, Jeremy D., Ying, Sarah H., Zesiewicz, Theresa A., Paulson, Henry L., Shakkottai, Vikram G., Bushara, Khalaf O., Kuo, Sheng-Han, Geschwind, Michael D., Xia, Guangbin, Pulst, Stefan M., Subramony, S. H., Ewenczyk, Claire, Brice, Alexis, Durr, Alexandra, Klockgether, Thomas, Ashizawa, Tetsuo, Tezenas du Montcel, Sophie

“…Background The Scale for Assessment and Rating of Ataxia (SARA) is a widely used clinical scale to assess cerebellar ataxia but faces some criticisms about the…”
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Clinical characteristics of patients with spinocerebellar ataxias 1, 2, 3 and 6 in the US; a prospective observational study by Ashizawa, Tetsuo, Figueroa, Karla P, Perlman, Susan L, Gomez, Christopher M, Wilmot, George R, Schmahmann, Jeremy D, Ying, Sarah H, Zesiewicz, Theresa A, Paulson, Henry L, Shakkottai, Vikram G, Bushara, Khalaf O, Kuo, Sheng-Han, Geschwind, Michael D, Xia, Guangbin, Mazzoni, Pietro, Krischer, Jeffrey P, Cuthbertson, David, Holbert, Amy Roberts, Ferguson, John H, Pulst, Stefan M, Subramony, S H

“…All spinocerebellar ataxias (SCAs) are rare diseases. SCA1, 2, 3 and 6 are the four most common SCAs, all caused by expanded polyglutamine-coding CAG repeats…”
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Progression of Friedreich ataxia: quantitative characterization over 5 years by Patel, Maya, Isaacs, Charles J., Seyer, Lauren, Brigatti, Karlla, Gelbard, Sarah, Strawser, Cassandra, Foerster, Debbie, Shinnick, Julianna, Schadt, Kimberly, Yiu, Eppie M., Delatycki, Martin B., Perlman, Susan, Wilmot, George R., Zesiewicz, Theresa, Mathews, Katherine, Gomez, Christopher M., Yoon, Grace, Subramony, Sub H., Brocht, Alicia, Farmer, Jennifer, Lynch, David R.

“…Objective Friedreich ataxia (FRDA) is a progressive neurodegenerative disorder of adults and children. This study analyzed neurological outcomes and changes to…”
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FXN methylation predicts expression and clinical outcome in Friedreich ataxia by Evans-Galea, Marguerite V., Carrodus, Nissa, Rowley, Simone M., Corben, Louise A., Tai, Geneieve, Saffery, Richard, Galati, John C., Wong, Nicholas C., Craig, Jeffrey M., Lynch, David R., Regner, Sean R., Brocht, Alicia F. D., Perlman, Susan L., Bushara, Khalaf O., Gomez, Christopher M., Wilmot, George R., Li, Lingli, Varley, Elizabeth, Delatycki, Martin B., Sarsero, Joseph P.

“…Objective: Friedreich ataxia (FA) is the most common ataxia and results from an expanded GAA repeat in the first intron of FXN. This leads to epigenetic…”
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Antioxidant use in Friedreich ataxia by Myers, Lauren, Farmer, Jennifer M, Wilson, Robert B, Friedman, Lisa, Tsou, Amy, Perlman, Susan L, Subramony, Sub H, Gomez, Christopher M, Ashizawa, Tetsuo, Wilmot, George R, Mathews, Katherine D, Balcer, Laura J, Lynch, David R

“…Abstract Many antioxidants have been suggested as potential treatments for Friedreich ataxia, but have not been tested in clinical trials. We found that a…”
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The S-Factor, a New Measure of Disease Severity in Spinocerebellar Ataxia: Findings and Implications by Selvadurai, Louisa P., Perlman, Susan L., Wilmot, George R., Subramony, Sub H., Gomez, Christopher M., Ashizawa, Tetsuo, Paulson, Henry L., Onyike, Chiadi U., Rosenthal, Liana S., Sair, Haris I., Kuo, Sheng-Han, Ratai, Eva-Maria, Zesiewicz, Theresa A., Bushara, Khalaf O., Öz, Gülin, Dietiker, Cameron, Geschwind, Michael D., Nelson, Alexandra B., Opal, Puneet, Yacoubian, Talene A., Nopoulos, Peggy C., Shakkottai, Vikram G., Figueroa, Karla P., Pulst, Stefan M., Morrison, Peter E., Schmahmann, Jeremy D.

“…Spinocerebellar ataxias (SCAs) are progressive neurodegenerative disorders, but there is no metric that predicts disease severity over time. We hypothesized…”
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The Cerebellar Cognitive Affective/Schmahmann Syndrome Scale in Spinocerebellar Ataxias by Selvadurai, Louisa P., Perlman, Susan L., Ashizawa, Tetsuo, Wilmot, George R., Onyike, Chiadi U., Rosenthal, Liana S., Shakkottai, Vikram G., Paulson, Henry L., Subramony, Sub H., Bushara, Khalaf O., Kuo, Sheng-Han, Dietiker, Cameron, Geschwind, Michael D., Nelson, Alexandra B., Gomez, Christopher M., Opal, Puneet, Zesiewicz, Theresa A., Hawkins, Trevor, Yacoubian, Talene A., Nopoulos, Peggy C., Sha, Sharon J., Morrison, Peter E., Figueroa, Karla P., Pulst, Stefan M., Schmahmann, Jeremy D.

“…The Cerebellar Cognitive Affective/Schmahmann Syndrome (CCAS) manifests as impaired executive control, linguistic processing, visual spatial function, and…”
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Analysis of the visual system in Friedreich ataxia by Seyer, Lauren A., Galetta, Kristin, Wilson, James, Sakai, Reiko, Perlman, Susan, Mathews, Katherine, Wilmot, George R., Gomez, Christopher M., Ravina, Bernard, Zesiewicz, Theresa, Bushara, Khalaf O., Subramony, S. H., Ashizawa, Tetsuo, Delatycki, Martin B., Brocht, Alicia, Balcer, Laura J., Lynch, David R.

“…To use optical coherence tomography (OCT) and contrast letter acuity to characterize vision loss in Friedreich ataxia (FRDA). High- and low-contrast letter…”
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Base cation fertilization and liming effects on nutrition and growth of Vermont sugar maple stands by Wilmot, Timothy R., Ellsworth, David S., Tyree, Melvin T.

“…Soil and foliar nutrition, crown condition, and wood growth were measured in three mature sugar maple stands in northern Vermont before and after fertilization…”
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Genetic Linkage Mapping of Allozyme Loci in Even- and Odd-year Pink Salmon (Oncorhynchus gorbuscha) by Matsuoka, M. P., Gharrett, A. J., Wilmot, R. L., Smoker, W. W.

“…We constructed genetic linkage maps of allozyme loci in even- and odd-year pink salmon (Oncorhynchus gorbuscha), using the total of 320 families (each female…”
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