Search Results - "Wilmes, A."

Dendrites help mitigate the plasticity-stability dilemma by Wilmes, Katharina A., Clopath, Claudia

“…With Hebbian learning ‘who fires together wires together’, well-known problems arise. Hebbian plasticity can cause unstable network dynamics and overwrite…”
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Inhibition as a Binary Switch for Excitatory Plasticity in Pyramidal Neurons by Wilmes, Katharina A, Sprekeler, Henning, Schreiber, Susanne

“…Synaptic plasticity is thought to induce memory traces in the brain that are the foundation of learning. To ensure the stability of these traces in the…”
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Cortical electrophysiological network dynamics of feedback learning by Cohen, Michael X, Wilmes, Katharina A, van de Vijver, Irene

“…Understanding the neurophysiological mechanisms of learning is important for both fundamental and clinical neuroscience. We present a neurophysiologically…”
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A coupled mechanical-charge/dipole molecular dynamics finite element method, with multi-scale applications to the design of graphene nano-devices by Wilmes, André A. R., Pinho, Silvestre T.

“…SUMMARYA new Molecular Dynamics Finite Element Method (MDFEM) with a coupled mechanical‐charge/dipole formulation is proposed. The equilibrium equations of…”
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Cyclosporine A kinetics in brain cell cultures and its potential of crossing the blood–brain barrier by Bellwon, P., Culot, M., Wilmes, A., Schmidt, T., Zurich, M.G., Schultz, L., Schmal, O., Gramowski-Voss, A., Weiss, D.G., Jennings, P., Bal-Price, A., Testai, E., Dekant, W.

“…•CyclosporinA (CsA) uptake into brain tissue limited by Pgp at the blood–brain barrier.•In 2 rodent brain models limited CsA uptake likely due to missing…”
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Kinetics and dynamics of cyclosporine A in three hepatic cell culture systems by Bellwon, P., Truisi, G.L., Bois, F.Y., Wilmes, A., Schmidt, T., Savary, C.C., Parmentier, C., Hewitt, P.G., Schmal, O., Josse, R., Richert, L., Guillouzo, A., Mueller, S.O., Jennings, P., Testai, E., Dekant, W.

“…•Kinetics of cyclosporine A were analyzed in 3 liver cell models over a 14-day period.•Sandwich primary rat and human hepatocytes and HepaRG cells were…”
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The bile acid deoxycholic acid (DCA) at neutral pH activates NF-κB and induces IL-8 expression in oesophageal cells in vitro by Jenkins, G.J.S., Harries, K., Doak, S.H., Wilmes, A., Griffiths, A.P., Baxter, J.N., Parry, J.M.

“…Barrett's oesophagus patients accumulate chromosomal defects during the histological progression to cancer, one of the most prominent of which is the…”
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Modelling plasticity in dendrites: from single cells to networks by Bono, Jacopo, Wilmes, Katharina A, Clopath, Claudia

“…•Neural network models often consist of point neurons, neglecting neuronal morphology.•Dendrites have been shown to accommodate various local plasticity…”
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Learning and attention increase visual response selectivity through distinct mechanisms by Poort, Jasper, Wilmes, Katharina A., Blot, Antonin, Chadwick, Angus, Sahani, Maneesh, Clopath, Claudia, Mrsic-Flogel, Thomas D., Hofer, Sonja B., Khan, Adil G.

“…Selectivity of cortical neurons for sensory stimuli can increase across days as animals learn their behavioral relevance and across seconds when animals switch…”
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Confidence and second-order errors in cortical circuits by Granier, Arno, Petrovici, Mihai A, Senn, Walter, Wilmes, Katharina A

“…Minimization of cortical prediction errors has been considered a key computational goal of the cerebral cortex underlying perception, action, and learning…”
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Nephrotoxic liability assessment using hiPSC-derived renal glomerular and proximal tubular epithelial cells by Wilmes, A., Chandrasekaran, V., Murphy, C., Jennings, P.

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P18-01: Application of iPSC-derived renal, hepatic, cardiac and endothelial models for mitochondrial toxicity testing by Carta, G., Naderlinger, E., Minten, Y., Bergstedt, N., Blom, S., Hendriks, F., Wilmes, A.

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P11-14 Characterisation of transport capacity of human iPSC-derived proximal tubular-like cells by Meijer, T., Raad, F., Leonard, M., Meier, F., Jennings, P., Wilmes, A.

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P12-30 Development of human iPSc derived renal models for mitochondrial toxicity detection by Carta, G., Naderlinger, E., Bergstedt, N.T., Minten, Y.S., Jennings, P., Wilmes, A.

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Response to Holroyd et al. : oscillation dynamics enable (the investigation of) networks by Cohen, Michael X, Wilmes, Katharina A, van de Vijver, Irene

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Cadmium induced temporal alterations measured in IPSC-derived proximal tubular cells by Singh, P., Chandrasekaran, V., Wilmes, A., Hardy, B., Jennings, P., Exner, T.E.

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Musculoskeletal and neuropsychiatric manifestations are the main source of persisting affection and organ damage in a German population of patients with systemic lupus erythematosus by Fiehn, C., Wilmes, A., Max, R., Willand, L., Löwe, B., Andrassy, K., Ho, A. D., Lorenz, H. -M.

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Providing Mobile Librarian Service to a College of Nursing to Increase Interactions and Transactions: One Wayne State University, Science and Technology Librarian's Experience by Wilmes, Nancy A.

“…A mobile librarian service to the Wayne State University College of Nursing was developed to provide in-person reference and research support. This service has…”
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Dissecting lineage specific oxidative stress response dynamics using high content imaging of the hiPSC HMOX1 fluorescent reporter line by ter Braak, B., Snijders, K., Fehér, A., Táncos, Z., Bock, I., Bourguignon, A., Niemeijer, M., van den Berk, L., Kobolák, J., Wilmes, A., Jennings, P., Verfaillie, C., Dinnyés, A., van de Water, B.

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Development of human iPSC-derived renal cell models for toxicity testing by Wilmes, A., Rauch, C., Kern, G., Feifel, L., Gstraunthaler, G., Jennings, P.

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