Search Results - "Willy, Patricia J"

Errα and Gabpa/b Specify PGC-1α-Dependent Oxidative Phosphorylation Gene Expression That Is Altered in Diabetic Muscle by Mootha, Vamsi K., Handschin, Christoph, Arlow, Dan, Xie, Xiaohui, St. Pierre, Julie, Sihag, Smita, Yang, Wenli, Altshuler, David, Puigserver, Pere, Patterson, Nick, Willy, Patricia J., Schulman, Ira G., Heyman, Richard A., Lander, Eric S., Spiegelman, Bruce M.

“…Recent studies have shown that genes involved in oxidative phosphorylation (OXPHOS) exhibit reduced expression in skeletal muscle of diabetic and prediabetic…”
Get full text

An oxysterol signalling pathway mediated by the nuclear receptor LXRα by Janowski, Bethany A, Willy, Patricia J, Devi, Thota Rama, Falck, J. R, Mangelsdorf, David J

“…Cholesterol and its oxysterol congeners are important constituents of cell membranes and function as intermediates in several crucial biosynthetic pathways…”
Get full text

Regulation of PPARγ Coactivator 1α (PGC-1α) Signaling by an Estrogen-Related Receptor α (ERRα) Ligand by Willy, Patricia J., Murray, Ian R., Qian, Jing, Busch, Brett B., Stevens, William C., Martin, Richard, Mohan, Raju, Zhou, Sihong, Ordentlich, Peter, Wei, Ping, Sapp, Douglas W., Horlick, Robert A., Heyman, Richard A., Schulman, Ira G., Spiegelman, Bruce M.

“…Peroxisome proliferator-activated receptor γ (PPARγ) coactivator 1α (PGC-1α) is a transcriptional coactivator that is a key component in the regulation of…”
Get full text

A Basal Transcription Factor That Activates or Represses Transcription by Willy, Patricia J., Kobayashi, Ryuji, Kadonaga, James T.

“…We have identified an activity that is required for transcription of downstream promoter element (DPE)-containing core promoters in vitro. The purified factor…”
Get full text

An internal region of the peroxisomal membrane protein PMP47 is essential for sorting to peroxisomes by McCammon, M.T, McNew, J.A, Willy, P.J, Goodman, J.M

“…Targeting sequences on peroxisomal membrane proteins have not yet been identified. We have attempted to find such a sequence within PMP47, a protein of the…”
Get full text

LXR, a nuclear receptor that defines a distinct retinoid response pathway by Willy, P J, Umesono, K, Ong, E S, Evans, R M, Heyman, R A, Mangelsdorf, D J

“…We have identified a new retinoid response pathway through which 9-cis retinoic acid (9cRA) activates transcription in the presence of LXR alpha, a member of…”
Get full text

Unique requirements for retinoid-dependent transcriptional activation by the orphan receptor LXR by Willy, P J, Mangelsdorf, D J

“…LXR is an orphan nuclear receptor that confers retinoid responsiveness to the retinoid X receptor (RXR) by its interaction on a specific response element…”
Get full text

Primary structures of two homologous subunits of PA28, a γ-interferon-inducible protein activator of the 20S proteasome by Joon Young Ahn, Nobuyuki Tanahashi, Kin-ya Akiyama, Hiroshi Hisamatsu, Chiseko Noda, Keiji Tanaka, Chin Ha Chung, Naoki Shibmara, Willy, Patricia J., Mott, Joni D., Slaughter, Clive A., DeMartino, George N.

“…The primary structures of two proteins that comprise PA28, an activator of the 20S proteasome, have been determined by cDNA cloning and sequencing. These…”
Get full text

A basal tanscription factor that activates or represses transcription by Willy, Patricia J, Kobayashi, Ryuji, Kadonaga, James T

“…We have identified an activity that is required for transcription of downstream promoter element (DPE)--containing core promoters in vitro. The purified factor…”
Get full text

Regulation of PPARgamma coactivator 1alpha (PGC-1alpha) signaling by an estrogen-related receptor alpha (ERRalpha) ligand by Willy, Patricia J, Murray, Ian R, Qian, Jing, Busch, Brett B, Stevens, Jr, William C, Martin, Richard, Mohan, Raju, Zhou, Sihong, Ordentlich, Peter, Wei, Ping, Sapp, Douglas W, Horlick, Robert A, Heyman, Richard A, Schulman, Ira G

“…Peroxisome proliferator-activated receptor gamma (PPARgamma) coactivator 1alpha (PGC-1alpha) is a transcriptional coactivator that is a key component in the…”
Get full text

Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle by Mootha, Vamsi K, Handschin, Christoph, Arlow, Dan, Xie, Xiaohui, St Pierre, Julie, Sihag, Smita, Yang, Wenli, Altshuler, David, Puigserver, Pere, Patterson, Nick, Willy, Patricia J, Schulman, Ira G, Heyman, Richard A, Lander, Eric S, Spiegelman, Bruce M

“…Recent studies have shown that genes involved in oxidative phosphorylation (OXPHOS) exhibit reduced expression in skeletal muscle of diabetic and prediabetic…”
Get full text

PA28, an activator of the 20 S proteasome, is inactivated by proteolytic modification at its carboxyl terminus by Ma, C.P., Willy, P.J., Slaughter, C.A., DeMartino, G.N.

“…PA28, a protein activator of the 20 S proteasome, was previously identified in soluble extracts of bovine red blood cells (Ma, C.-P., Slaughter, C. A., and…”
Get full text

Subcellular Localization and Sequence of Sea Urchin Kinesin Heavy Chain: Evidence for Its Association with Membranes in the Mitotic Apparatus and Interphase Cytoplasm by Wright, Brent D., Henson, John H., Wedaman, Karen P., Willy, Patricia J., Morand, Janice N., Scholey, Jonathan M.

“…Kinesin was previously immunolocalized to mitotic apparatuses (MAs) of early sea urchin blastomeres. Here we report evidence that this MA-associated motor…”
Get full text