Search Results - "Willoughby, Scott R"

Effect of Atrial Fibrillation on Atrial Thrombogenesis in Humans: Impact of Rate and Rhythm by Lim, Han S., MBBS, PhD, Willoughby, Scott R., PhD, Schultz, Carlee, BHlthSc(Hons), Gan, Cheryl, BSc, Alasady, Muayad, MBChB, Lau, Dennis H., MBBS, PhD, Leong, Darryl P., MBBS, MPH, PhD, Brooks, Anthony G., PhD, Young, Glenn D., MBBS, Kistler, Peter M., MBBS, PhD, Kalman, Jonathan M., MBBS, PhD, Worthley, Matthew I., MBBS, PhD, Sanders, Prashanthan, MBBS, PhD

“…Objectives We sought to assess the effect of atrial fibrillation (AF) on atrial thrombogenesis in humans by determining the impact of rate and rhythm…”
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Detrimental Effects of Energy Drink Consumption on Platelet and Endothelial Function by Worthley, Matthew I., MBBS, PhD, Prabhu, Anisha, BSc(Hons), De Sciscio, Paolo, BHSci(Hons), Schultz, Carlee, BHSci, Sanders, Prashanthan, MBBS, PhD, Willoughby, Scott R., PhD

“…Abstract Background Energy drink consumption has been anecdotally linked with sudden cardiac death and, more recently, myocardial infarction. As myocardial…”
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Time Course of Inflammation, Myocardial Injury, and Prothrombotic Response After Radiofrequency Catheter Ablation for Atrial Fibrillation by Lim, Han S, Schultz, Carlee, Dang, Jerry, Alasady, Muayad, Lau, Dennis H, Brooks, Anthony G, Wong, Christopher X, Roberts-Thomson, Kurt C, Young, Glenn D, Worthley, Matthew I, Sanders, Prashanthan, Willoughby, Scott R

“…BACKGROUND—Inflammation has been linked to the genesis of stroke in atrial fibrillation (AF) and is implicated in early recurrent arrhythmia after AF ablation…”
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Aortic stiffness in lone atrial fibrillation: a novel risk factor for arrhythmia recurrence by Lau, Dennis H, Middeldorp, Melissa E, Brooks, Anthony G, Ganesan, Anand N, Roberts-Thomson, Kurt C, Stiles, Martin K, Leong, Darryl P, Abed, Hany S, Lim, Han S, Wong, Christopher X, Willoughby, Scott R, Young, Glenn D, Kalman, Jonathan M, Abhayaratna, Walter P, Sanders, Prashanthan

“…Recent community-based research has linked aortic stiffness to the development of atrial fibrillation. We posit that aortic stiffness contributes to adverse…”
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Successful catheter ablation decreases platelet activation and improves endothelial function in patients with atrial fibrillation by Lim, Han S., MBBS, PhD, Willoughby, Scott R., PhD, Schultz, Carlee, BHlthSc(Hons), Chakrabarty, Adhiraj, BSc(Hons), BMBS, Alasady, Muayad, MBChB, Lau, Dennis H., MBBS, PhD, FHRS, Roberts-Thomson, Kurt C., MBBS, PhD, Worthley, Matthew I., MBBS, PhD, Young, Glenn D., MBBS, Sanders, Prashanthan, MBBS, PhD, FHRS

“…Background Nonvalvular atrial fibrillation (AF) confers a five-fold increased risk of stroke. Whether catheter ablation (CA) subsequently decreases…”
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Atrial platelet reactivity in patients with atrial fibrillation by Willoughby, Scott R., PhD, Roberts-Thomson, Ross L., BMedSci(Hons), Lim, Han S., MBBS, Schultz, Carlee, BHSc(Hons), Prabhu, Anisha, BSc(Hons), De Sciscio, Paolo, BHSc(Hons), Wong, Christopher X, Worthley, Matthew I., MBBS, PhD, Sanders, Prashanthan, MBBS, PhD

“…Background Atrial fibrillation (AF) is associated with an increased risk of thrombus formation in the left but not the right atrium. The mechanisms underlying…”
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Clopidogrel Improves Microvascular Endothelial Function in Subjects with Stable Coronary Artery Disease by Willoughby, Scott R., PhD, Luu, Lee-Jen, MBBS, Cameron, James D., MBBS, Nelson, Adam J., MBBS, Schultz, Carlee D., BHthSc(Hons), Worthley, Stephen G., MBBS, Worthley, Matthew I., MBBS

“…Background Clopidogrel therapy has recently been shown to reduce cardiovascular events in patients with stable vascular disease. This benefit may be due to…”
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Determinants of Occurrence of Aortic Sclerosis in an Aging Population by Ngo, Doan T.M., BPharm, PhD, Sverdlov, Aaron L., MBBS, Willoughby, Scott R., PhD, Nightingale, Angus K., MD, Chirkov, Yuliy Y., PhD, McNeil, John J., MBBS, PhD, Horowitz, John D., MBBS, PhD

“…Objectives We sought to identify clinical, physiological, and biochemical correlates, including markers of endothelial dysfunction and of tissue nitric oxide…”
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Assessment of endothelial function in atrial fibrillation: utility of peripheral arterial tonometry by Wong, Christopher X, Lim, Han S, Schultz, Carlee D, Sanders, Prashanthan, Worthley, Matthew I, Willoughby, Scott R

“…Summary 1. Endothelial function is an independent predictor of adverse cardiovascular outcomes. The evaluation of endothelial function via changes in vessel…”
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Influence of ethnic background on left atrial markers of inflammation, endothelial function and tissue remodelling by Ruediger, Carlee D., John, Bobby, Kumar, Sathesh, Lim, Han S., Rangnekar, Geetanjali, Roberts-Thomson, Kurt C., Young, Glenn D., Chase, David, Sanders, Prashanthan, Willoughby, Scott R.

“…It has been suggested that ethnicity can make a significant difference to the likelihood of thromboembolic stroke related to atrial fibrillation. Ethnic…”
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Ramipril Sensitizes Platelets to Nitric Oxide by Willoughby, Scott R., PhD, Rajendran, Sharmalar, MBBS, PhD, Chan, Wai P., MBBS, Procter, Nathan, BSc, Leslie, Sue, RN, Liberts, Elizabeth A., PhD, Heresztyn, Tamila, BSc, Chirkov, Yuliy Y., PhD, Horowitz, John D., MBBS, PhD

“…Objectives Using 2 sequential studies in HOPE (Heart Outcomes Prevention Evaluation) study–type patients, the aims of this study were: 1) to test the…”
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Induction of Platelet Formation from Megakaryocytoid Cells by Nitric Oxide by Battinelli, Elisabeth, Willoughby, Scott R., Foxall, Thomas, Valeri, C. Robert, Loscalzo, Joseph

“…Although the growth factors that regulate megakaryocytopoiesis are well known, the molecular determinants of platelet formation from mature megakaryocytes…”
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Ramipril Sensitizes Platelets to Nitric Oxide: Implications for Therapy in High-Risk Patients by WILLOUGHBY, Scott R, RAJENDRAN, Sharmalar, CHAN, Wai P, PROCTER, Nathan, LESLIE, Sue, LIBERTS, Elizabeth A, HERESZTYN, Tamila, CHIRKOV, Yuliy Y, HOROWITZ, John D

“…Using 2 sequential studies in HOPE (Heart Outcomes Prevention Evaluation) study-type patients, the aims of this study were: 1) to test the hypothesis that…”
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Antiplatelet therapy in acute coronary syndromes: current agents and impact on patient outcomes by Tayeb, Hussam M, Nelson, Adam J, Willoughby, Scott R, Worthley, Matthew I

“…Platelets play a central role in atherothrombosis and subsequent development of acute coronary syndromes (ACS). The understanding of this process has driven a…”
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Endothelial function, oxidative stress and inflammatory studies in chronic coronary slow flow phenomenon patients by Kopetz, Victoria, Kennedy, Jennifer, Heresztyn, Tamila, Stafford, Irene, Willoughby, Scott R, Beltrame, John F

“…The coronary slow flow phenomenon (CSFP) is associated with coronary microvascular dysfunction although the responsible mechanisms are unknown. This study…”
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Polycystic ovary syndrome is associated with severe platelet and endothelial dysfunction in both obese and lean subjects by Rajendran, Sharmalar, Willoughby, Scott R, Chan, Wai Ping A, Liberts, Elizabeth A, Heresztyn, Tamila, Saha, Mrinal, Marber, Michael S, Norman, Robert J, Horowitz, John D

“…Abstract Platelet hyporesponsiveness to the anti-aggregatory effects of nitric oxide (NO) occurs commonly in association with myocardial ischemia and coronary…”
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The deleterious effects of hyperglycemia on platelet function in diabetic patients with acute coronary syndromes : Mediation by superoxide production, resolution with intensive insulin administration by WORTHLEY, Matthew I, HOLMES, Andrew S, WILLOUGHBY, Scott R, KUCIA, Angela M, HERESZTYN, Tamila, STEWART, Simon, CHIRKOV, Yuliy Y, ZEITZ, Christopher J, HOROWITZ, John D

“…This study sought to assess the determinants of platelet nitric oxide (NO) responsiveness in diabetic patients admitted with acute coronary syndromes (ACS) and…”
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Cardiovascular magnetic resonance-derived aortic distensibility: validation and observed regional differences in the elderly by Nelson, Adam J, Worthley, Stephen G, Cameron, James D, Willoughby, Scott R, Piantadosi, Cynthia, Carbone, Angelo, Dundon, Benjamin K, Leung, Michael C, Hope, Sarah A, Meredith, Ian T, Worthley, Matthew I

“…OBJECTIVEApplanation tonometry evaluation of pulse wave velocity is widely accepted as the ‘gold standard’ method for noninvasively assessing arterial…”
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The Effect of Acute Onset Atrial Fibrillation and Rapid Atrial Rates on Markers of Thrombogenesis in the Human Left Atrium by S. Lim, Han, R. Willoughby, Scott, Schultz, Carlee, Alasady, Muayad, H. Lau, Dennis, C. Roberts-Thomson, Kurt, D. Young, Glenn, Sanders, Prashanthan

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Inflammation, Myocardial Injury and Prothrombotic Response Following Catheter Ablation for Atrial Fibrillation by S. Lim, Han, R. Willoughby, Scott, Schultz, Carlee, Alasady, Muayad, Worthley, Matthew, D. Young, Glenn, Sanders, Prashanthan

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