Search Results - "Willott, Ruth"
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Mutations in Troponin that cause HCM, DCM AND RCM: What can we learn about thin filament function?
Published in Journal of molecular and cellular cardiology (01-05-2010)“…Abstract Troponin (Tn) is a critical regulator of muscle contraction in cardiac muscle. Mutations in Tn subunits are associated with hypertrophic, dilated and…”
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Progressive multifocal leukoencephalopathy masquerading as cerebellar infarction
Published in Age and ageing (01-07-2016)“…Progressive neurological signs and symptoms, in immunocompromised individuals, could be due to progressive multifocal leukoencephalopathy (PML). We report the…”
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Dilated Cardiomyopathy Mutations in Three Thin Filament Regulatory Proteins Result in a Common Functional Phenotype
Published in The Journal of biological chemistry (05-08-2005)“…Dilated cardiomyopathy (DCM), characterized by cardiac dilatation and contractile dysfunction, is a major cause of heart failure. Inherited DCM can result from…”
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Alterations in Thin Filament Regulation Induced by a Human Cardiac Troponin T Mutant That Causes Dilated Cardiomyopathy Are Distinct from Those Induced by Troponin T Mutants That Cause Hypertrophic Cardiomyopathy
Published in The Journal of biological chemistry (25-10-2002)“…We have compared the in vitro regulatory properties of recombinant human cardiac troponin reconstituted using wild type troponin T with troponin containing the…”
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Exploring the variability of sarcopenia prevalence in a research population using different disease definitions
Published in Aging clinical and experimental research (01-10-2023)“…Background Sarcopenia is the progressive loss of muscle mass and function with age. A number of different sarcopenia definitions have been proposed and…”
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Engagement in research during specialist geriatric medicine training: results of a national trainee survey
Published in Clinical medicine (London, England) (01-11-2022)“…Meaningful ageing research across the UK is dependent on a network of engaged geriatricians. The research in geriatric specialty training (RGST) survey aimed…”
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Growing research in geriatric medicine: a trainee perspective
Published in Age and ageing (24-08-2020)“…Abstract Growing research in geriatric medicine is a priority area. Currently, involvement of geriatricians in research lags behind other specialties. The…”
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Using Social Media and Web-Based Networking in Collaborative Research: Protocol for the Geriatric Medicine Research Collaborative
Published in JMIR research protocols (01-10-2018)“…Traditional pathways to promote research collaboration typically take years to expand beyond individual institutions. Social media and online networking…”
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Increasing frailty is associated with higher prevalence and reduced recognition of delirium in older hospitalised inpatients: results of a multi-centre study
Published in European geriatric medicine (01-04-2023)“…Key summary points Aim Describe frailty in hospital inpatients with delirium. Findings Patients with delirium were more frail than patients without delirium…”
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Retrospective delirium ascertainment from case notes: a retrospective cohort study
Published in BMJ open (28-05-2021)“…ObjectivesThis study sets out to ascertain if recognition of delirium impacts on patient outcomes.DesignRetrospective cohort study.SettingUnscheduled…”
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What is meant by active disease in the NICE recommendation on use of combination therapy in early RA?
Published in Rheumatology (Oxford, England) (01-05-2012)Get full text
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