Search Results - "Willmarth, Nicole"

The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion by Liu, Manran, Sakamaki, Toshiyuki, Casimiro, Mathew C., Willmarth, Nicole E., Quong, Andrew A., Ju, Xiaoming, Ojeifo, John, Jiao, Xuanmao, Yeow, Wen-Shuz, Katiyar, Sanjay, Shirley, L. Andrew, Joyce, David, Lisanti, Michael P., Albanese, Christopher, Pestell, Richard G.

“…Abstract The role of mammary epithelial cell (MEC) NF-κB in tumor progression in vivo is unknown, as murine NF-κB components and kinases either are required…”
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microRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signaling by Yu, Zuoren, Willmarth, Nicole E, Zhou, Jie, Katiyar, Sanjay, Wang, Min, Liu, Yang, McCue, Peter A, Quong, Andrew A, Lisanti, Michael P, Pestell, Richard G

“…microRNAs are thought to regulate tumor progression and invasion via direct interaction with target genes within cells. Here the microRNA17/20 cluster is shown…”
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Autocrine and Juxtacrine Effects of Amphiregulin on the Proliferative, Invasive, and Migratory Properties of Normal and Neoplastic Human Mammary Epithelial Cells by Willmarth, Nicole E., Ethier, Stephen P.

“…Amphiregulin (AR) autocrine loops have been associated with several types of cancer. We demonstrate that SUM149 breast cancer cells have a self-sustaining AR…”
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NCCN Guidelines® Insights: Central Nervous System Cancers, Version 2.2022 by Horbinski, Craig, Nabors, Louis Burt, Portnow, Jana, Baehring, Joachim, Bhatia, Ankush, Bloch, Orin, Brem, Steven, Butowski, Nicholas, Cannon, Donald M, Chao, Samuel, Chheda, Milan G, Fabiano, Andrew J, Forsyth, Peter, Gigilio, Pierre, Hattangadi-Gluth, Jona, Holdhoff, Matthias, Junck, Larry, Kaley, Thomas, Merrell, Ryan, Mrugala, Maciej M, Nagpal, Seema, Nedzi, Lucien A, Nevel, Kathryn, Nghiemphu, Phioanh L, Parney, Ian, Patel, Toral R, Peters, Katherine, Puduvalli, Vinay K, Rockhill, Jason, Rusthoven, Chad, Shonka, Nicole, Swinnen, Lode J, Weiss, Stephanie, Wen, Patrick Yung, Willmarth, Nicole E, Bergman, Mary Anne, Darlow, Susan

“…The NCCN Guidelines for Central Nervous System (CNS) Cancers focus on management of the following adult CNS cancers: glioma (WHO grade 1, WHO grade 2-3…”
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c-Jun Induces Mammary Epithelial Cellular Invasion and Breast Cancer Stem Cell Expansion by Jiao, Xuanmao, Katiyar, Sanjay, Willmarth, Nicole E., Liu, Manran, Ma, Xiaojing, Flomenberg, Neal, Lisanti, Michael P., Pestell, Richard G.

“…The molecular mechanisms governing breast tumor cellular self-renewal contribute to breast cancer progression and therapeutic resistance. The ErbB2 oncogene is…”
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Including the patient voice in the development and implementation of patient‐reported outcomes in cancer clinical trials by Addario, Bonnie, Geissler, Jan, Horn, Marcia K., Krebs, Linda U., Maskens, Deborah, Oliver, Kathy, Plate, Ananda, Schwartz, Erin, Willmarth, Nicole

“…Context Patient‐reported outcomes (PROs) are used in parallel with clinical evidence to inform decisions made by industry, clinicians, regulators, health…”
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Cell Fate Determination Factor Dachshund Reprograms Breast Cancer Stem Cell Function by Wu, Kongming, Jiao, Xuanmao, Li, Zhaoming, Katiyar, Sanjay, Casimiro, Mathew C., Yang, Wancai, Zhang, Qiong, Willmarth, Nicole E., Chepelev, Iouri, Crosariol, Marco, Wei, Zhang, Hu, Junbo, Zhao, Keji, Pestell, Richard G.

“…The cell fate determination factor Dachshund was cloned as a dominant inhibitor of the hyperactive epidermal growth factor receptor ellipse. The expression of…”
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Cyclin D1 Integrates Estrogen-Mediated DNA Damage Repair Signaling by ZHIPING LI, KE CHEN, KATZENELLENBOGEN, John A, PESTELL, Richard G, XUANMAO JIAO, CHENGUANG WANG, WILLMARTH, Nicole E, CASIMIRO, Mathew C, WEIHUA LI, XIAOMING JU, SUNG HOON KIM, LISANTI, Michael P

“…The cyclin D1 gene encodes the regulatory subunit of a holoenyzme that phosphorylates the retinoblastoma protein (pRb) and nuclear respiratory factor (NRF1)…”
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Altered EGFR localization and degradation in human breast cancer cells with an amphiregulin/EGFR autocrine loop by Willmarth, Nicole E., Baillo, Andrea, Dziubinski, Michele L., Wilson, Kristy, Riese, David J., Ethier, Stephen P.

“…The epidermal growth factor receptor (EGFR) and its ligand amphiregulin (AR) have been shown to be co-over expressed in breast cancer. We have previously shown…”
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Cross-sectional survey of patients, caregivers, and physicians on diagnosis and treatment of brain metastases by Kim, Albert E, Wang, Gi-Ming, Waite, Kristin A, Elder, Scott, Fine, Avery, Ahluwalia, Manmeet S, Brat, Daniel, Mehta, Minesh P, Page, Robin, Dunbar, Erin, Calderone, Heather M, Robins, Debra Signer, DeVitto, Ralph, Willmarth, Nicole E, Barnholtz-Sloan, Jill S, Brastianos, Priscilla K

“…Abstract Background The development of brain metastases (BM) is one of the most feared complications of cancer due to the substantial neurocognitive morbidity…”
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Amphiregulin as a Novel Target for Breast Cancer Therapy by Willmarth, Nicole E, Ethier, Stephen P

“…Amphiregulin, an EGF family growth factor, binds and activates the epidermal growth factor receptor (EGFR or ErbB1). Activation of the EGFR by amphiregulin can…”
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Activation of a Nuclear Factor κB/Interleukin-1 Positive Feedback Loop by Amphiregulin in Human Breast Cancer Cells by Streicher, Katie L., Willmarth, Nicole E., Garcia, Jose, Boerner, Julie L., Dewey, T. Gregory, Ethier, Stephen P.

“…We have recently shown that an amphiregulin-mediated autocrine loop is responsible for growth factor–independent proliferation, motility, and invasive capacity…”
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Nuclear Factor-κB Enhances ErbB2-Induced Mammary Tumorigenesis and Neoangiogenesis in Vivo by Liu, Manran, Ju, Xiaoming, Willmarth, Nicole E, Casimiro, Mathew C, Ojeifo, John, Sakamaki, Toshiyuki, Katiyar, Sanjay, Jiao, Xuanmao, Popov, Vladimir M, Yu, Zuoren, Wu, Kongming, Joyce, David, Wang, Chenguang, Pestell, Richard G

“…The (HER2/Neu) ErbB2 oncogene is commonly overexpressed in human breast cancer and is sufficient for mammary tumorigenesis in transgenic mice. Nuclear factor…”
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How to live with a meningioma: experiences, symptoms, and challenges reported by patients by Nassiri, Farshad, Suppiah, Suganth, Wang, Justin Z, Badhiwala, Jetan H, Juraschka, Kyle, Meng, Ying, Nejad, Romina, Au, Karolyn, Willmarth, Nicole E, Cusimano, Michael, Zadeh, Gelareh

“…Abstract Background We aimed to explore gaps in the care of meningioma patients that could improve quality of care by better understanding symptoms experienced…”
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A critical role for CCR2/MCP-1 interactions in the development of idiopathic pneumonia syndrome after allogeneic bone marrow transplantation by Hildebrandt, Gerhard C., Duffner, Ulrich A., Olkiewicz, Krystyna M., Corrion, Leigh A., Willmarth, Nicole E., Williams, Debra L., Clouthier, Shawn G., Hogaboam, Cory M., Reddy, Pavan R., Moore, Bethany B., Kuziel, William A., Liu, Chen, Yanik, Gregory, Cooke, Kenneth R.

“…Idiopathic pneumonia syndrome (IPS) is a major complication after allogeneic bone marrow transplantation (allo-BMT) and involves the infiltration of donor…”
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A role for tumor necrosis factor-α-mediated endothelial apoptosis in the development of experimental idiopathic pneumonia syndrome by GERBITZ, Armin, NICKOLOFF, Brian J, COOKE, Kenneth R, OLKIEWICZ, Krystyna, WILLMARTH, Nicole E, HILDEBRANDT, Gerhard, CHEN LIU, KOBZIK, Lester, EISSNER, Günther, HOLLER, Ernst, FERRARA, James L. M

“…Idiopathic pneumonia syndrome (IPS) is a frequent and often fatal complication of allogeneic bone marrow transplantation (BMT). We have previously shown that…”
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Chromosomal instability and lack of cyclin E regulation in hCdc4 mutant human breast cancer cells by Willmarth, Nicole E, Albertson, Donna G, Ethier, Stephen P

“…Cyclin E, a G1 cyclin essential for G1-S phase transition, is known to have a profound effect on tumorigenesis. Elevated levels of cyclin E have been…”
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Intraneural colchicine inhibition of adenoviral and adeno-associated viral vector remote spinal cord gene delivery by BOULIS, Nicholas M, WILLMARTH, Nicole E, RUTKA, James T, SONG, Debbie K, FELDMAN, Eva L, IMPERIALE, Michael J, BARTOLOMEI, Juan, PIEPMEIER, Joseph M, ZLOKOVIC, Berislav V, HODGE, Charles J, JR

“…The mechanism of remote viral gene delivery to the spinal cord is unknown. The present experiment demonstrates that intraneural injection of colchicine is…”
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A role for CD54 (intercellular adhesion molecule-1) in leukocyte recruitment to the lung during the development of experimental idiopathic pneumonia syndrome by GERBITZ, Armin, EWING, Patricia, HOLLER, Ernst, RENFENG GUO, WARD, Peter A, COOKE, Kenneth R, OLKIEWICZ, Krystyna, WILLMARTH, Nicole E, WILLIAMS, Debra, HILDEBRANDT, Gerhard, WILKE, Andrea, CHEN LIU, EISSNER, Günther, ANDREESEN, Reinhard

“…Idiopathic pneumonia syndrome (IPS) is a frequently fatal complication of allogeneic bone marrow transplantation (BMT). IPS is associated with elevated…”
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Defining interventions and metrics to improve diversity in CNS clinical trial participation: A SNO and RANO effort by Budhu, Joshua A, Chukwueke, Ugonma N, Jackson, Sadhana, Lee, Eudocia Q, McFaline-Figueroa, J Ricardo, Willmarth, Nicole, Dalmage, Mahalia, Kawachi, Ichiro, Arons, David, Chang, Susan M, Galanis, Evanthia, Hervey-Jumper, Shawn L, Wen, Patrick Y, Porter, Alyx B

“…Despite major strides in cancer research and therapy, these advances have not been equitable across race and ethnicity. Historically marginalized groups (HMG)…”
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