Search Results - "Willmann, Matthias"

Human commensals producing a novel antibiotic impair pathogen colonization by Zipperer, Alexander, Konnerth, Martin C., Laux, Claudia, Berscheid, Anne, Janek, Daniela, Weidenmaier, Christopher, Burian, Marc, Schilling, Nadine A., Slavetinsky, Christoph, Marschal, Matthias, Willmann, Matthias, Kalbacher, Hubert, Schittek, Birgit, Brötz-Oesterhelt, Heike, Grond, Stephanie, Peschel, Andreas, Krismer, Bernhard

“…The nasal commensal bacterium Staphylococcus lugdunensis produces a novel cyclic peptide antibiotic, lugdunin, that inhibits colonization by S. aureus in…”
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Distinct impact of antibiotics on the gut microbiome and resistome: a longitudinal multicenter cohort study by Willmann, Matthias, Vehreschild, Maria J G T, Biehl, Lena M, Vogel, Wichard, Dörfel, Daniela, Hamprecht, Axel, Seifert, Harald, Autenrieth, Ingo B, Peter, Silke

“…The selection pressure exercised by antibiotic drugs is an important consideration for the wise stewardship of antimicrobial treatment programs. Treatment…”
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Prognostic Value of Gut Microbiome for Conversion from Mild Cognitive Impairment to Alzheimer's Disease Dementia within 4 Years: Results from the AlzBiom Study by Laske, Christoph, Müller, Stephan, Munk, Matthias H J, Honold, Iris, Willmann, Matthias, Peter, Silke, Schoppmeier, Ulrich

“…Alterations in the gut microbiome are associated with the pathogenesis of Alzheimer's disease (AD) and can be used as a diagnostic measure. However,…”
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Genomic characterisation of clinical and environmental Pseudomonas putida group strains and determination of their role in the transfer of antimicrobial resistance genes to Pseudomonas aeruginosa by Peter, Silke, Oberhettinger, Philipp, Schuele, Leonard, Dinkelacker, Ariane, Vogel, Wichard, Dörfel, Daniela, Bezdan, Daniela, Ossowski, Stephan, Marschal, Matthias, Liese, Jan, Willmann, Matthias

“…Pseudomonas putida is a Gram-negative, non-fermenting bacterium frequently encountered in various environmental niches. P. putida rarely causes disease in…”
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Antibiotic Selection Pressure Determination through Sequence-Based Metagenomics by Willmann, Matthias, El-Hadidi, Mohamed, Huson, Daniel H, Schütz, Monika, Weidenmaier, Christopher, Autenrieth, Ingo B, Peter, Silke

“…The human gut forms a dynamic reservoir of antibiotic resistance genes (ARGs). Treatment with antimicrobial agents has a significant impact on the intestinal…”
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Pathogenicity of Clinical OXA-48 Isolates and Impact of the OXA-48 IncL Plasmid on Virulence and Bacterial Fitness by Hamprecht, Axel, Sommer, Julian, Willmann, Matthias, Brender, Christina, Stelzer, Yvonne, Krause, Felix F., Tsvetkov, Tsvetan, Wild, Florian, Riedel-Christ, Sara, Kutschenreuter, Julia, Imirzalioglu, Can, Gonzaga, Aitor, Nübel, Ulrich, Göttig, Stephan

“…OXA-48 is the most common carbapenemase in Enterobacterales in Germany and one of the most frequent carbapenemases worldwide. Several reports have associated…”
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Cholesterol and host cell surface proteins contribute to cell-cell fusion induced by the Burkholderia type VI secretion system 5 by Whiteley, Liam, Haug, Maria, Klein, Kristina, Willmann, Matthias, Bohn, Erwin, Chiantia, Salvatore, Schwarz, Sandra

“…Following escape into the cytoplasm of host cells, Burkholderia pseudomallei and the related species Burkholderia thailandensis employ the type VI secretion…”
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Signature of Alzheimer's Disease in Intestinal Microbiome: Results From the AlzBiom Study by Laske, Christoph, Müller, Stephan, Preische, Oliver, Ruschil, Victoria, Munk, Matthias H J, Honold, Iris, Peter, Silke, Schoppmeier, Ulrich, Willmann, Matthias

“…Changes in intestinal microbiome composition have been described in animal models of Alzheimer's disease (AD) and AD patients. Here we investigated how well…”
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Transcriptomic Basis of Serum Resistance and Virulence Related Traits in XDR P. aeruginosa Evolved Under Antibiotic Pressure in a Morbidostat Device by Javed, Mumina, Jentzsch, Benedikt, Heinrich, Maximilian, Ueltzhoeffer, Viola, Peter, Silke, Schoppmeier, Ulrich, Angelov, Angel, Schwarz, Sandra, Willmann, Matthias

“…Colistin is a last resort antibiotic against the critical status pathogen . Virulence and related traits such as biofilm formation and serum resistance after…”
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Analysis of a long-term outbreak of XDR Pseudomonas aeruginosa: a molecular epidemiological study by Willmann, Matthias, Bezdan, Daniela, Zapata, Luis, Susak, Hana, Vogel, Wichard, Schröppel, Klaus, Liese, Jan, Weidenmaier, Christopher, Autenrieth, Ingo B, Ossowski, Stephan, Peter, Silke

“…Here we report on a long-term outbreak from 2009 to 2012 with an XDR Pseudomonas aeruginosa on two wards at a university hospital in southern Germany…”
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Tracking of Antibiotic Resistance Transfer and Rapid Plasmid Evolution in a Hospital Setting by Nanopore Sequencing by Peter, Silke, Bosio, Mattia, Gross, Caspar, Bezdan, Daniela, Gutierrez, Javier, Oberhettinger, Philipp, Liese, Jan, Vogel, Wichard, Dörfel, Daniela, Berger, Lennard, Marschal, Matthias, Willmann, Matthias, Gut, Ivo, Gut, Marta, Autenrieth, Ingo, Ossowski, Stephan

“…Infections with multidrug-resistant bacteria often leave limited or no treatment options. The transfer of antimicrobial resistance genes (ARG) carrying…”
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Laboratory markers of disease severity in Plasmodium knowlesi infection: a case control study by Willmann, Matthias, Ahmed, Atique, Siner, Angela, Wong, Ing Tien, Woon, Lu Chan, Singh, Balbir, Krishna, Sanjeev, Cox-Singh, Janet

“…Plasmodium knowlesi malaria causes severe disease in up to 10% of cases in Malaysian Borneo and has a mortality rate of 1 - 2%. However, laboratory markers…”
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Molecular Evolution of Extensively Drug-Resistant (XDR) Pseudomonas aeruginosa Strains From Patients and Hospital Environment in a Prolonged Outbreak by Buhl, Michael, Kästle, Christina, Geyer, André, Autenrieth, Ingo B, Peter, Silke, Willmann, Matthias

“…In this study, we aimed to elucidate a prolonged outbreak of extensively drug-resistant (XDR) , at two adjacent hospitals over a time course of 4 years. Since…”
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Time Series Analysis as a Tool To Predict the Impact of Antimicrobial Restriction in Antibiotic Stewardship Programs Using the Example of Multidrug-Resistant Pseudomonas aeruginosa by WILLMANN, Matthias, MARSCHAL, Matthias, HÖLZL, Florian, SCHRÖPPEL, Klaus, AUTENRIETH, Ingo B, PETER, Silke

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Disease progression in Plasmodium knowlesi malaria is linked to variation in invasion gene family members by Ahmed, Atique M, Pinheiro, Miguel M, Divis, Paul C, Siner, Angela, Zainudin, Ramlah, Wong, Ing Tien, Lu, Chan Woon, Singh-Khaira, Sarina K, Millar, Scott B, Lynch, Sean, Willmann, Matthias, Singh, Balbir, Krishna, Sanjeev, Cox-Singh, Janet

“…Emerging pathogens undermine initiatives to control the global health impact of infectious diseases. Zoonotic malaria is no exception. Plasmodium knowlesi, a…”
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Members of a mammalian SNARE complex interact in the endoplasmic reticulum in vivo and are found in COPI vesicles by Verrier, Sophie Estelle, Willmann, Matthias, Wenzel, Dirk, Winter, Ulrike, von Mollard, Gabriele Fischer, Söling, Hans-Dieter

“…Retrograde traffic between the Golgi apparatus and the endoplasmic reticulum (ER) is largely mediated by COPI-coated transport vesicles. In mammalian cells,…”
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Evaluation of the Accelerate Pheno System for Fast Identification and Antimicrobial Susceptibility Testing from Positive Blood Cultures in Bloodstream Infections Caused by Gram-Negative Pathogens by Marschal, Matthias, Bachmaier, Johanna, Autenrieth, Ingo, Oberhettinger, Philipp, Willmann, Matthias, Peter, Silke

“…Bloodstream infections (BSI) are an important cause of morbidity and mortality. Increasing rates of antimicrobial-resistant pathogens limit treatment options,…”
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Prevalence and risk factors associated with colonization and infection of extensively drug-resistant Pseudomonas aeruginosa: a systematic review by Buhl, Michael, Peter, Silke, Willmann, Matthias

“…Pseudomonas aeruginosa is a Gram-negative human pathogen with extensively drug-resistant (XDR) strains emerging in hospitals across the globe. This systematic…”
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Endometriose: neue Hoffnung für die Diagnostik?: microRNA-Signatur in Speichelproben by Willmann, Matthias

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Translational metagenomics and the human resistome: confronting the menace of the new millennium by Willmann, Matthias, Peter, Silke

“…The increasing threat of antimicrobial resistance poses one of the greatest challenges to modern medicine. The collection of all antimicrobial resistance genes…”
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