Search Results - "Willis, W."

Accurate detection of shared genetic architecture from GWAS summary statistics in the small-sample context by Willis, Thomas W, Wallace, Chris

“…Assessment of the genetic similarity between two phenotypes can provide insight into a common genetic aetiology and inform the use of pleiotropy-informed,…”
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Mutually orthogonal pyrrolysyl-tRNA synthetase/tRNA pairs by Willis, Julian C. W., Chin, Jason W.

“…Genetically encoding distinct non-canonical amino acids (ncAAs) into proteins synthesized in cells requires mutually orthogonal aminoacyl-tRNA synthetase…”
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Engineered triply orthogonal pyrrolysyl–tRNA synthetase/tRNA pairs enable the genetic encoding of three distinct non-canonical amino acids by Dunkelmann, Daniel L., Willis, Julian C. W., Beattie, Adam T., Chin, Jason W.

“…Expanding and reprogramming the genetic code of cells for the incorporation of multiple distinct non-canonical amino acids (ncAAs), and the encoded…”
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Prevalence of Parkinson’s disease across North America by Marras, C., Beck, J. C., Bower, J. H., Roberts, E., Ritz, B, Ross, G. W., Abbott, R. D., Savica, R., Van Den Eeden, S. K., Willis, A. W., Tanner, CM

“…Estimates of the prevalence of Parkinson’s disease in North America have varied widely and many estimates are based on small numbers of cases and from small…”
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Compact zinc finger base editors that edit mitochondrial or nuclear DNA in vitro and in vivo by Willis, Julian C. W., Silva-Pinheiro, Pedro, Widdup, Lily, Minczuk, Michal, Liu, David R.

“…DddA-derived cytosine base editors (DdCBEs) use programmable DNA-binding TALE repeat arrays, rather than CRISPR proteins, a split double-stranded DNA cytidine…”
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Incidence of Parkinson disease in North America by Willis, A. W., Roberts, E., Beck, J. C., Fiske, B., Ross, W., Savica, R., Van Den Eeden, S. K., Tanner, C. M., Marras, C.

“…Parkinson disease (PD) is the second most common age-related neurodegenerative condition diagnosed in North America. We recently demonstrated, using multiple…”
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Self‐reported visual dysfunction in Parkinson disease: the Survey of Health, Ageing and Retirement in Europe by Hamedani, A. G, Willis, A. W

“…Background and purpose Visual dysfunction is a non‐motor symptom of Parkinson disease (PD), but its prevalence is unknown as population‐based data on the…”
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Dorsal root potentials and dorsal root reflexes : a double-edged sword by WILLIS, W. D

“…The nature of dorsal root reflexes (DRRs) and their possible role in peripheral inflammation and the consequent hyperalgesia are reviewed. The history of DRRs…”
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Neurologist care in Parkinson disease: A utilization, outcomes, and survival study by WILLIS, A. W, SCHOOTMAN, M, EVANOFF, B. A, PERLMUTTER, J. S, RACETTE, B. A

“…To investigate the utilization of neurologist providers in the treatment of patients with Parkinson disease (PD) in the United States and determine whether…”
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Interfacility Transfers for Seizure-Related Emergencies in the United States by Acton, Emily K., Blank, Leah J., Willis, Allison W., Hamedani, Ali G.

“…Interfacility transfer protocols are important for seizure-related emergencies, the cause of approximately 1% of all emergency department (ED) visits in the…”
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Neurologist-associated reduction in PD-related hospitalizations and health care expenditures by WILLIS, Allison W, SCHOOTMAN, Mario, TRAN, Rebecca, KUNG, Nathan, EVANOFF, Bradley A, PERLMUTTER, Joel S, RACETTE, Brad A

“…To investigate the impact of neurologist care on Parkinson disease (PD)-related hospitalizations. Recent data indicate that neurologist treatment in PD may be…”
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Associations between Anticholinergic Burden and Adverse Health Outcomes in Parkinson Disease by Crispo, James A G, Willis, Allison W, Thibault, Dylan P, Fortin, Yannick, Hays, Harlen D, McNair, Douglas S, Bjerre, Lise M, Kohen, Dafna E, Perez-Lloret, Santiago, Mattison, Donald R, Krewski, Daniel

“…Elderly adults should avoid medications with anticholinergic effects since they may increase the risk of adverse events, including falls, delirium, and…”
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Attitudes and beliefs towards medication burden and deprescribing in Parkinson disease by Pham Nguyen, Thanh Phuong, Thibault, Dylan, Hamedani, Ali G, Willis, Allison W

“…Deprescribing of potentially inappropriate medications is recommended for older adults and may improve health outcomes and quality of life in persons living…”
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Dopamine agonists and risk of lung cancer in patients with restless legs syndrome by Hernandez‐Con, Pilar, Shults, Justine, Willis, Allison W., Yang, Yu‐Xiao

“…Purpose To examine the association between long‐term use of dopamine agonists (DAs) and the risk of lung cancer in patients with restless legs syndrome (RLS)…”
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Low continuation of antipsychotic therapy in Parkinson disease – intolerance, ineffectiveness, or inertia? by Pham Nguyen, Thanh Phuong, Abraham, Danielle S, Thibault, Dylan, Weintraub, Daniel, Willis, Allison W

“…Abstract Background Antipsychotics are used in Parkinson disease (PD) to treat psychosis, mood, and behavioral disturbances. Commonly used antipsychotics…”
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Unique characteristics of end-of-life hospitalizations in Parkinson disease by Aamodt, Whitley W, Dahodwala, Nabila, Bilker, Warren B, Farrar, John T, Willis, Allison W

“…Persons with Parkinson disease (PD) are hospitalized at higher rates, have longer lengths of stay, and are more likely to die in the hospital than age-matched…”
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Immunosuppressants and risk of Parkinson disease by Racette, Brad A., Gross, Anat, Vouri, Scott Martin, Camacho‐Soto, Alejandra, Willis, Allison W., Searles Nielsen, Susan

“…We performed a population‐based case–control study of United States Medicare beneficiaries age 60–90 in 2009 with prescription data (48,295 incident Parkinson…”
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Patient and Physician Perceptions of Virtual Visits for Parkinson's Disease: A Qualitative Study by Mammen, Jennifer R, Elson, Molly J, Java, James J, Beck, Christopher A, Beran, Denise B, Biglan, Kevin M, Boyd, Cynthia M, Schmidt, Peter N, Simone, Richard, Willis, Allison W, Dorsey, E Ray

“…Background and Introduction: Delivering care through telemedicine directly into the patient's home is increasingly feasible, valuable, and beneficial. However,…”
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Investigating the Effects of Dietary Probiotic Feeding Regimens on Broiler Chicken Production and Campylobacter jejuni Presence by Willis, W.L, Reid, L

“…An experiment was conducted to investigate the effect of restricted feeding of a commercially available probiotic diet on production/processing performance,…”
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Metal Emissions and Urban Incident Parkinson Disease: A Community Health Study of Medicare Beneficiaries by Using Geographic Information Systems by Willis, Allison W., Evanoff, Bradley A., Lian, Min, Galarza, Aiden, Wegrzyn, Andrew, Schootman, Mario, Racette, Brad A.

“…Parkinson disease associated with farming and exposure to agricultural chemicals has been reported in numerous studies; little is known about Parkinson disease…”
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