Search Results - "Willis, Todd"

Brief report: Production of anti-SARS-CoV-2 hyperimmune globulin from convalescent plasma by Vandeberg, Peter, Cruz, Maria, Diez, Jose Maria, Merritt, W Keither, Santos, Benjamin, Trukawinski, Susan, Wellhouse, Andrea, Jose, Marta, Willis, Todd

“…In late 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus emerged in China and quickly spread into a worldwide pandemic. Prior to…”
Get full text

Non‐additive effect on thrombin generation when a plasma‐derived factor VIII/von Willebrand factor (FVIII/VWF) is combined with emicizumab in vitro by Bravo, María Isabel, Raventós, Aida, Pérez, Alba, Costa, Montserrat, Willis, Todd

“…Background Emicizumab is an alternative non‐factor approach for treating patients with hemophilia A. However, there is a potential risk of thrombotic events…”
Get full text

Combination of emicizumab and factor VIII has no additive effects after reaching normal coagulation levels by Bravo, Maria‐Isabel, Raventós, Aida, Pérez, Alba, Costa, Montserrat, Willis, Todd

Get full text

Anti-Severe Acute Respiratory Syndrome Coronavirus 2 Hyperimmune Immunoglobulin Demonstrates Potent Neutralization and Antibody-Dependent Cellular Cytotoxicity and Phagocytosis Through N and S Proteins by Díez, José María, Romero, Carolina, Cruz, María, Vandeberg, Peter, Merritt, William Keither, Pradenas, Edwards, Trinité, Benjamin, Blanco, Julià, Clotet, Bonaventura, Willis, Todd, Gajardo, Rodrigo

“…Abstract Background Although coronavirus disease 2019 (COVID-19) vaccinations have provided a significant reduction in infections, effective COVID-19…”
Get full text

Ascites reduction and anti-inflammatory effects after albumin infusion for the management of cirrhosis: evidence from an animal model by Horrillo, Raquel, Mestre, Anna, Alcaraz, Estefania, Varo, Guillermo Fernández, Jiménez, Wladimiro, Gonzalo, Ricardo, Vidal, Jordi, Arroyo, Vicente, Clària, Joan, Willis, Todd, Costa, Montserrat

Get full text

Ex Vivo Evaluation of the Effect of Plasma-Derived Factor VIII/Von Willebrand Factor in Patients with Severe Hemophilia_A on Prophylaxis with Emicizumab By Thrombin Generation Assay by Bravo, Maria-Isabel, Raventós, Aida, Pérez, Alba, G Arias-Salgado, Elena, Alvarez Román, María Teresa, Butta, Nora V., Jiménez-Yuste, Víctor, Costa, Montserrat, Willis, Todd

“…Introduction: Hemophilia A (HA) patients under emicizumab prophylaxis treatment may require the concomitant use of procoagulant factors for breakthrough…”
Get full text

Combination of emicizumab and factor VIII has no additive effects after reaching normal coagulation levels: Response to J Puetz (Are there additive effects between emicizumab and factor VIII?) by Maria‐Isabel Bravo, Raventós, Aida, Pérez, Alba, Costa, Montserrat, Willis, Todd

Get full text

Production of anti‐SARS‐CoV‐2 hyperimmune globulin from convalescent plasma by Vandeberg, Peter, Cruz, Maria, Diez, Jose Maria, Merritt, W. Keither, Santos, Benjamin, Trukawinski, Susan, Wellhouse, Andrea, Jose, Marta, Willis, Todd

“…Background In late 2019, the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) virus emerged in China and quickly spread into a worldwide pandemic…”
Get full text

Long-term 20% albumin administration normalizes the plasma albumin binding capacity in patients with decompensated cirrhosis by Horrillo, Raquel, Mestre, Anna, Ortiz, Ana Maria, Pérez, Alba, Raventós, Aida, Torres, Mireia, Páez, Antonio, Arroyo, Vicente, Fernandez, Javier, Clària, Joan, Willis, Todd, Costa, Montserrat

Get full text

SAT207 - Long-term 20% albumin administration normalizes the plasma albumin binding capacity in patients with decompensated cirrhosis by Horrillo, Raquel, Mestre, Anna, Ortiz, Ana Maria, Pérez, Alba, Raventós, Aida, Torres, Mireia, Páez, Antonio, Arroyo, Vicente, Fernandez, Javier, Clària, Joan, Willis, Todd, Costa, Montserrat

Get full text

Characterization of an Anti-Ebola Virus Hyperimmune Globulin Derived From Convalescent Plasma by Ciencewicki, Jonathan M, Herbert, Andrew S, Storm, Nadia, Josleyn, Nicole M, Huie, Kathleen E, McKay, Lindsay G A, Griffiths, Anthony, Dye, John M, Willis, Todd, Arora, Vikram

“…Convalescent plasma has been used to treat many viral diseases including Ebola. The manufacture of a purified anti-Ebola virus (EBOV) intravenous…”
Get full text

Plasma‐derived FVIII/VWF complex shows higher protection against inhibitors than isolated FVIII after infusion in haemophilic patients: A translational study by Bravo, Maria Isabel, Pérez, Alba, Raventós, Aida, Grancha, Salvador, Jorquera, Juan Ignacio, Butta, Nora Viviana, Álvarez‐Román, Maria Teresa, Costa, Montserrat, Willis, Todd, Jiménez‐Yuste, Victor

“…Introduction Presence of von Willebrand factor (VWF) in FVIII concentrates offers protection against neutralizing inhibitors in haemophilia A (HA). Whether…”
Get full text

Immune globulin subcutaneous, human 20% solution (Xembify®), a new high concentration immunoglobulin product for subcutaneous administration by Alonso, William, Vandeberg, Pete, Lang, John, Yuziuk, Jeffrey, Silverstein, Rebecca, Stokes, Kenya, McBride, Dennis, Cruz, Maria, Burns, Doug, Merritt, W. Keither, Willis, Todd, Jorquera, Juan I.

“…Immune globulin subcutaneous, human 20% solution (IGSC-C 20%, Xembify®)—a new 20% immunoglobulin (IgG) liquid product for subcutaneous (SC) administration—has…”
Get full text

Purification and biochemical characterization of atroxase, a nonhemorrhagic fibrinolytic protease from western diamondback rattlesnake venom by Willis, Todd W, Tu, Anthony T

“…Crotalus atrox venom contains a variety of proteases which render fibrinogen incoagulable and solubilize fibrin. One of these proteases was purified by using…”
Get full text

Comparison of the liquid and lyophilized formulations of Prolastin®-C for Alpha1-Antitrypsin deficiency: Biochemical characteristics, pharmacokinetics, safety and neoantigenicity in rabbits by Arora, Vikram, Cruz, Maria, Lang, John, Klos, Anthony M., Merritt, W. Keither, Price, Jeffrey, Taylor, George, Vandeberg, Pete, Wee, Kevin, Willis, Todd

“…Multiple analytical and preclinical studies were performed to compare the biochemical characteristics, pharmacokinetics (PK), safety and neoantigenicity of a…”
Get full text

Immunoglobulin G from single plasma donor in immune globulin intravenous causes false positive pyrogen test by Zervos, Clark, Zimmerman, Thomas P., Willis, Todd, Flexman, Greg, Srivastava, Jyoti, Silverstein, Rebecca, Williams, Melanie, Vandeberg, Pete, Culp, Jennifer L., Burns, Doug, Barham, Vickie, Durham, Amy, Malinzak, David A.

“…A sudden, unprecedented failure of USP rabbit pyrogen tests for multiple 10% IGIV-C lots prompted a thorough investigation of the root cause for this…”
Get full text

Comparison of the liquid and lyophilized formulations of Prolastin®-C for Alpha 1 -Antitrypsin deficiency: Biochemical characteristics, pharmacokinetics, safety and neoantigenicity in rabbits by Arora, Vikram, Cruz, Maria, Lang, John, Klos, Anthony M, Merritt, W Keither, Price, Jeffrey, Taylor, George, Vandeberg, Pete, Wee, Kevin, Willis, Todd

“…Multiple analytical and preclinical studies were performed to compare the biochemical characteristics, pharmacokinetics (PK), safety and neoantigenicity of a…”
Get full text

Pathogen safety profile of a 10% IgG preparation manufactured using a depth filtration-modified process by Barnette, Deborah, Roth, Nathan J., Hotta, JoAnn, Cai, Kang, Gall, Michelle, Hartwell, Randy, Kent, Jonathan D., Willis, Todd

“…Gamunex®-C is a highly purified liquid 10% IgG preparation manufactured by a process that includes caprylate precipitation and incubation, and chromatography…”
Get full text

Effects of Continuous Exposure of SH-SY5Y Neuroblastoma Cells to Chlorpyrifos on Neuronal Differentiation: Implications for Neurotoxicity by Todd, Spencer Willis

“…The acute toxicity of the organophosphorus insecticide chlorpyrifos (CPF) results from the irreversible inhibition of acetylcholinesterase (AChE). However,…”
Get full text

New bounds to estimate the sedimentation velocities of monodisperse and binary colloidal suspensions by Gilleland, Willis Todd

“…We devise a theoretical technique to compute the average sedimentation velocity of a suspension consisting of either monodisperse spheres or a binary mixture…”
Get full text