Search Results - "Willis, Sean"

Characterization of a novel intrinsically radiopaque Drug-eluting Bead for image-guided therapy: DC Bead LUMI by Ashrafi, Koorosh, Tang, Yiqing, Britton, Hugh, Domenge, Orianne, Blino, Delphine, Bushby, Andrew J., Shuturminska, Kseniya, den Hartog, Mark, Radaelli, Alessandro, Negussie, Ayele H., Mikhail, Andrew S., Woods, David L., Krishnasamy, Venkatesh, Levy, Elliot B., Wood, Bradford J., Willis, Sean L., Dreher, Matthew R., Lewis, Andrew L.

“…We have developed a straightforward and efficient method of introducing radiopacity into Polyvinyl alcohol (PVA)-2-Acrylamido-2-methylpropane sulfonic acid…”
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Long-term biocompatibility, imaging appearance and tissue effects associated with delivery of a novel radiopaque embolization bead for image-guided therapy by Sharma, Karun V, Bascal, Zainab, Kilpatrick, Hugh, Ashrafi, Koorosh, Willis, Sean L, Dreher, Matthew R, Lewis, Andrew L

“…Abstract The objective of this study was to undertake a comprehensive long-term biocompatibility and imaging assessment of a new intrinsically radiopaque bead…”
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Radiopaque Drug-Eluting Beads for Transcatheter Embolotherapy: Experimental Study of Drug Penetration and Coverage in Swine by Dreher, Matthew R., PhD, Sharma, Karun V., MD, PhD, Woods, David L., BS, Reddy, Goutham, MD, Tang, Yiqing, PhD, Pritchard, William F., MD, PhD, Chiesa, Oscar A., DVM, PhD, Karanian, John W., PhD, Esparza, Juan A., LTAG, Donahue, Danielle, BS, Levy, Elliot B., MD, Willis, Sean L., PhD, Lewis, Andrew L., PhD, Wood, Bradford J., MD

“…Abstract Purpose To determine local doxorubicin levels surrounding radiopaque drug-eluting beads (DEBs) in normal swine liver and kidney following…”
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In situ evaluation of spatiotemporal distribution of doxorubicin from Drug-eluting Beads in a tissue mimicking phantom by Caine, Marcus, Bian, Shuning, Tang, Yiqing, Garcia, Pedro, Henman, Alexander, Dreher, Matthew, Daly, Dan, Carlisle, Robert, Stride, Eleanor, Willis, Sean L., Lewis, Andrew L.

“…Understanding the intra-tumoral distribution of chemotherapeutic drugs is extremely important in predicting therapeutic outcome. Tissue mimicking gel phantoms…”
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Handling and performance characteristics of a new small caliber radiopaque embolic microsphere by Lewis, Andrew L., Caine, Marcus, Garcia, Pedro, Ashrafi, Koorosh, Tang, Yiqing, Hinchcliffe, Lorcan, Guo, Wei, Bascal, Zainab, Kilpatrick, Hugh, Willis, Sean L.

“…The in vitro and in vivo handling and performance characteristics of a small caliber radiopaque embolic microsphere, 40–90 μm DC Bead LUMI™ (LUMI40‐90), were…”
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DC bead: in vitro characterization of a drug-delivery device for transarterial chemoembolization by Lewis, Andrew L, Gonzalez, M Victoria, Lloyd, Andrew W, Hall, Brenda, Tang, Yiqing, Willis, Sean L, Leppard, Simon W, Wolfenden, Laura C, Palmer, Rosemary R, Stratford, Peter W

“…The purpose of this investigation is to present the in vitro characterization and detailed drug-loading procedure for DC Bead, a microsphere product that can…”
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Bench-to-clinic development of imageable drug-eluting embolization beads: finding the balance by Lewis, Andrew L, Willis, Sean L, Dreher, Matthew R, Tang, Yiqing, Ashrafi, Koorosh, Wood, Bradford J, Levy, Elliot B, Sharma, Karun V, Negussie, Ayele H, Mikhail, Andrew S

“…This review describes the historical development of an imageable spherical embolic agent and focuses on work performed in collaboration between Biocompatibles…”
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Mapping Drug Dose Distribution on CT Images Following Transarterial Chemoembolization with Radiopaque Drug-Eluting Beads in a Rabbit Tumor Model by Mikhail, Andrew S, Pritchard, William F, Negussie, Ayele H, Krishnasamy, Venkatesh P, Amchin, Daniel B, Thompson, John G, Wakim, Paul G, Woods, David, Bakhutashvili, Ivane, Esparza-Trujillo, Juan A, Karanian, John W, Willis, Sean L, Lewis, Andrew L, Levy, Elliot B, Wood, Bradford J

“…Purpose To correlate bead location and attenuation on CT images with the quantity and distribution of drug delivered to the liver following transarterial…”
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Pharmacokinetic and safety study of doxorubicin-eluting beads in a porcine model of hepatic arterial embolization by Lewis, Andrew L, Taylor, Rachel R, Hall, Brenda, Gonzalez, M Victoria, Willis, Sean L, Stratford, Peter W

“…To present the pathologic and pharmacokinetic findings from hepatic embolization in a porcine model comparing doxorubicin-eluting beads with bland embolization…”
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A Novel Inherently Radiopaque Bead for Transarterial Embolization to Treat Liver Cancer - A Pre-clinical Study by Duran, Rafael, Sharma, Karun, Dreher, Matthew R, Ashrafi, Koorosh, Mirpour, Sahar, Lin, MingDe, Schernthaner, Ruediger E, Schlachter, Todd R, Tacher, Vania, Lewis, Andrew L, Willis, Sean, den Hartog, Mark, Radaelli, Alessandro, Negussie, Ayele H, Wood, Bradford J, Geschwind, Jean-François H

“…Embolotherapy using microshperes is currently performed with soluble contrast to aid in visualization. However, administered payload visibility dimishes soon…”
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Preparation of Radiopaque Drug-Eluting Beads for Transcatheter Chemoembolization by Johnson, Carmen Gacchina, PhD, Tang, Yiqing, PhD, Beck, Avi, MD, Dreher, Matthew R., PhD, Woods, David L., MS, Negussie, Ayele H., MSc, Donahue, Danielle, BS, Levy, Elliot B., MD, Willis, Sean L., PhD, Lewis, Andrew L., PhD, Wood, Bradford J., MD, Sharma, Karun V., MD, PhD

“…Abstract Purpose To develop a simple method to produce radiopaque drug-eluting microspheres (drug-eluting beads [DEBs]) that could be incorporated into the…”
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Comparison of microsphere penetration with LC Bead LUMI™ versus other commercial microspheres by Caine, Marcus, Zhang, Xunli, Hill, Martyn, Guo, Wei, Ashrafi, Koorosh, Bascal, Zainab, Kilpatrick, Hugh, Dunn, Anthony, Grey, David, Bushby, Rosemary, Bushby, Andrew, Willis, Sean L, Dreher, Matthew R, Lewis, Andrew L

“…The purpose of this study was to evaluate LC Bead LUMI™ (40-90µm and 70-150µm) in order to determine if their increased resistance to compression influences…”
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Development of “Imageable” Beads for Transcatheter Embolotherapy by Sharma, Karun V., MD, PhD, Dreher, Matthew R., PhD, Tang, Yiqing, PhD, Pritchard, William, MD, PhD, Chiesa, Oscar A., DVM, PhD, Karanian, John, PhD, Peregoy, Jennifer, BS, Orandi, Babak, MD, Woods, David, BS, Donahue, Danielle, BS, Esparza, Juan, LTAG, Jones, Guy, MD, Willis, Sean L., PhD, Lewis, Andrew L., PhD, Wood, Bradford J., MD

“…Purpose To develop and characterize radiopaque embolization microspheres capable of in vivo detection with intraprocedural fluoroscopy and computed tomography…”
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Development of an on-animal separation-based sensor for monitoring drug metabolism in freely roaming sheep by Scott, David E, Willis, Sean D, Gabbert, Seth, Johnson, David, Naylor, Erik, Janle, Elsa M, Krichevsky, Janice E, Lunte, Craig E, Lunte, Susan M

“…The development of an on-animal separation-based sensor that can be employed for monitoring drug metabolism in a freely roaming sheep is described. The system…”
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Safety and Tolerability of Topotecan-Eluting Radiopaque Microspheres for Hepatic Chemoembolization in a Rabbit Preclinical Model by Mikhail, Andrew S., Levy, Elliot B., Krishnasamy, Venkatesh P., Woods, David L., Esparza-Trujillo, Juan A., Bakhutashvili, Ivane, Banovac, Filip, Wakim, Paul G., Negussie, Ayele H., Tang, Yiqing, Henman, Alexander, Willis, Sean L., Karanian, John W., Pritchard, William F., Lewis, Andrew L., Wood, Bradford J.

“…Purpose Topotecan is a camptothecin analogue with potential advantages over irinotecan for transarterial chemoembolization (TACE) of hepatic colorectal…”
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A novel phosphorylcholine-coated contact lens for extended wear use by Willis, Sean L, Court, Jane L, Redman, Richard P, Wang, Jin-Hai, Leppard, Simon W, O’Byrne, Vincent J, Small, Sharon A, Lewis, Andrew L, Jones, Stephen A, Stratford, Peter W

“…The preparation and characterisation of a new phosphorylcholine (PC)-coated silicone hydrogel contact lens for use in extended wear is described. The…”
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Abstract 4145256: Urban Greenspace Exposure, Stress, and Cardiovascular Function by Stopforth, Cameron, Simpson, Anna, Willis, Sean, Smith, Ted, Bhatnagar, Aruni, Keith, Rachel

“…Abstract only Introduction: Healthy urban environments are essential for improving cardiovascular health. Although exposure to wild green surroundings has been…”
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Impact of Donor Hepatectomy Time During Organ Procurement in Donation After Circulatory Death Liver Transplantation: The United Kingdom Experience by Farid, Shahid G, Attia, Magdy S, Vijayanand, Dhakshina, Upasani, Vivek, Barlow, Adam D, Willis, Sean, Hidalgo, Ernest, Ahmad, Niaz

“…BACKGROUND.No data exist to evaluate how hepatectomy time (HT), in the context of donation after cardiac death (DCD) procurement, impacts short- and long-term…”
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Drug loading and elution from a phosphorylcholine polymer-coated coronary stent does not affect long-term stability of the coating in vivo by Lewis, Andrew L, Willis, Sean L, Small, Sharon A, Hunt, Stuart R, O'byrne, Vincent, Stratford, Peter W

“…A drug eluting coronary stent was developed for use in preclinical and clinical trial evaluation. The stent was coated with a phosphorylcholine (PC)-based…”
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Evaluation of novel formulations for transarterial chemoembolization: combining elements of Lipiodol emulsions with Drug-eluting Beads by Caine, Marcus, Chung, Ting, Kilpatrick, Hugh, Bascal, Zainab, Willis, Sean, Tang, Yiqing, de Baere, Thierry, Dreher, Matthew, Lewis, Andrew

“…There are currently two methods widely used in clinical practice to perform transarterial chemoembolization (TACE). One is based on mixing an aqueous drug with…”
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