Search Results - "Willis, Charlene"
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A tractable experimental model for study of human and animal scabies
Published in PLoS neglected tropical diseases (20-07-2010)“…Scabies is a parasitic skin infestation caused by the burrowing mite Sarcoptes scabiei. It is common worldwide and spreads rapidly under crowded conditions,…”
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Probing the equatorial groove of the hookworm protein and vaccine candidate antigen, Na-ASP-2
Published in The international journal of biochemistry & cell biology (01-05-2014)“…[Display omitted] Hookworm activation-associated secreted proteins can be structurally classified into at least three different groups. The hallmark feature of…”
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Characterization of a Serine Protease Homologous to House Dust Mite Group 3 Allergens from the Scabies Mite Sarcoptes scabiei
Published in The Journal of biological chemistry (04-12-2009)“…The scabies mite, Sarcoptes scabiei var. hominis, infests human skin, causing allergic reactions and facilitating bacterial infection by Streptococcus sp.,…”
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Insights into the membrane interactions of the saposin-like proteins Na-SLP-1 and Ac-SLP-1 from human and dog hookworm
Published in PloS one (03-10-2011)“…Saposin-like proteins (SAPLIPs) from soil-transmitted helminths play pivotal roles in host-pathogen interactions and have a high potential as targets for…”
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Quantitative PCR-based genome size estimation of the astigmatid mites Sarcoptes scabiei, Psoroptes ovis and Dermatophagoides pteronyssinus
Published in Parasites & vectors (04-01-2012)“…The lack of genomic data available for mites limits our understanding of their biology. Evolving high-throughput sequencing technologies promise to deliver…”
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Novel scabies mite serpins inhibit the three pathways of the human complement system
Published in PloS one (11-07-2012)“…Scabies is a parasitic infestation of the skin by the mite Sarcoptes scabiei that causes significant morbidity worldwide, in particular within socially…”
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Molecular characterization of Schistosoma mansoni tegument annexins and comparative analysis of antibody responses following parasite infection
Published in Molecular and biochemical parasitology (01-12-2019)“…•Structural and immunobiochemical characterization of four homologous annexins expressed in Schistosoma mansoni tegument.•Gene expression profiles of four…”
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Immunogenicity, antibody responses and vaccine efficacy of recombinant annexin B30 against Schistosoma mansoni
Published in Parasite immunology (01-03-2020)“…Aims Schistosomes infect approximately 250 million people worldwide. To date, there is no effective vaccine available for the prevention of schistosome…”
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Structure–function analysis of apical membrane‐associated molecules of the tegument of schistosome parasites of humans: prospects for identification of novel targets for parasite control
Published in British journal of pharmacology (01-04-2015)“…Neglected tropical diseases are a group of some 17 diseases that afflict poor and predominantly rural people in developing nations. One significant disease…”
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STEMfit: Student Centric Innovation to Improve STEM Educational Engagement Using Physical Activity, Wearable Technologies and Lean Methodologies
Published in Proceedings (01-06-2020)“…School-based education programmes are increasingly focused on the teaching of skills thought to be more suitable for an increasingly technological society…”
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Role of Chikungunya nsP3 in Regulating G3BP1 Activity, Stress Granule Formation and Drug Efficacy
Published in Archives of medical research (01-01-2021)“…Ras-GTPase activating protein SH3-domain-binding proteins (G3BP) are a small family of RNA-binding proteins implicated in regulating gene expression. Changes…”
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Speed cameras for the prevention of road traffic injuries and deaths
Published in Cochrane database of systematic reviews (01-01-2010)“…It is estimated that by 2020, road traffic crashes will have moved from ninth to third in the world ranking of burden of disease, as measured in disability…”
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Speed cameras for the prevention of road traffic injuries and deaths
Published in Cochrane database of systematic reviews (10-11-2010)“…It is estimated that by 2020, road traffic crashes will have moved from ninth to third in the world ranking of burden of disease, as measured in disability…”
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Crystal structure and immunological properties of the first annexin from Schistosoma mansoni: insights into the structural integrity of the schistosomal tegument
Published in The FEBS journal (01-02-2014)“…Schistosomiasis is a major parasitic disease of humans, second only to malaria in its global impact. The disease is caused by digenean trematodes that infest…”
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Lysosome-associated membrane glycoprotein (LAMP) – preliminary study on a hidden antigen target for vaccination against schistosomiasis
Published in Scientific reports (16-10-2015)“…Our previously reported gene atlasing of schistosome tissues revealed transcripts that were highly enriched in the digestive tract of Schistosoma mansoni …”
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Transcriptional profiling of the oesophageal gland region of male worms of Schistosoma mansoni
Published in Molecular and biochemical parasitology (01-09-2014)“…There were 122 genes, including those associated with lipid metabolism, haemoglobin digestion and some micro-exon genes up regulated in the oesophageal gland…”
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Alcohol ignition interlock programmes for reducing drink driving recidivism
Published in Cochrane database of systematic reviews (18-10-2004)“…An ignition interlock device is part of a multi-dimensional programme aimed at reducing recidivism in convicted drink drivers. To operate a vehicle equipped…”
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A genome-wide analysis of annexins from parasitic organisms and their vectors
Published in Scientific reports (11-10-2013)“…In this study, we conduct an in-depth analysis of annexin proteins from a diverse range of invertebrate taxa, including the major groups that contain the…”
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Population pharmacokinetics of tacrolimus in adult kidney transplant recipients
Published in Clinical pharmacology and therapeutics (01-12-2002)“…Objectives The aims of this study were to investigate the population pharmacokinetics of tacrolimus in adult kidney transplant recipients and to identify…”
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Structural Mechanisms of Inactivation in Scabies Mite Serine Protease Paralogues
Published in Journal of molecular biology (24-07-2009)“…The scabies mite ( Sarcoptes scabiei) is a parasite responsible for major morbidity in disadvantaged communities and immuno-compromised patients worldwide. In…”
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