Search Results - "Willis, C L"

Partial recovery of the damaged rat blood–brain barrier is mediated by adherens junction complexes, extracellular matrix remodeling and macrophage infiltration following focal astrocyte loss by Willis, C.L, Camire, R.B, Brule, S.A, Ray, D.E

“…Highlights • Paracellular VE-cadherin and β-catenin maintained in the absence of GFAP-astrocytes. • Demonstrates a different regulation mechanism for adherens…”
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A size selective vascular barrier in the rat area postrema formed by perivascular macrophages and the extracellular matrix by Willis, C.L, Garwood, C.J, Ray, D.E

“…Abstract The fenestrated microvasculature of the area postrema shows a less restrictive blood–brain barrier than is found in other areas of the CNS. We have…”
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Chronic inflammatory pain and the neurovascular unit: a central role for glia in maintaining BBB integrity? by Willis, C L, Brooks, T A, Davis, T P

“…Pain is a complex phenomenon involving both a peripheral innate immune response and a CNS response as well as activation of the hypothalamic-pituitary-adrenal…”
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Synthesis of fluorinated amino acids by Sutherland, A, Willis, C L

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Accuracy and cost-effectiveness of single-view echocardiographic screening for suspected mitral valve prolapse by Kimura, B J, Scott, R, Willis, C L, DeMaria, A N

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Synthesis of probes for the active site of leucine dehydrogenase by Sutherland, Andrew, Willis, Christine L.

“…A series of novel 3-substituted 2-oxobutanoic acids were prepared and incubated with leucine dehydrogenase giving in one case both a kinetic resolution at C-3…”
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Nutritional aspects of dissimilatory sulfate reduction in the human large intestine by Willis, C.L, Cummings, J.H, Neale, G, Gibson, G.R

“…In contrast to other anaerobic ecosystems, such as marine and estuarine sediments, there is a lack of information on the nutritional requirements of human gut…”
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Neuroprotective effect of free radical scavengers on beta-N-oxalylamino-L-alanine (BOAA)-induced neuronal damage in rat hippocampus by Willis, C L, Meldrum, B S, Nunn, P B, Anderton, B H, Leigh, P N

“…The neurotoxin beta-N-oxalylamino-L-alanine (BOAA), found in Lathyrus sativus seeds, is thought to be the causative agent of neurolathyrism. We have…”
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Negative correlation between oral malodour and numbers and activities of sulphate-reducing bacteria in the human mouth by Willis, C.L., Gibson, G.R., Holt, J., Allison, C.

“…The majority of cases of oral malodour are thought to be due to bacterial activities in the mouth, but many of the bacterial species responsible have not been…”
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L-trans-2,3-Pyrrolidine Dicarboxylate: Characterization of a Novel Excitotoxin by WILLIS, C.L, HUMPHREY, J.M, KOCH, H.P, HART, J.A, BLAKELY, T, RALSTON, L, BAKER, C.A, SHIM, S, KADRI, M, CHAMBERLIN, A.R, BRIDGES, R.J

“…This study investigated the in vitro and in vivo excitotoxic properties of a novel conformationally constrained analogue of L- trans-2,3-pyrrolidine…”
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Abstracts of the 22nd International Isotope Society (UK Group) Symposium: synthesis and applications of labelled compounds 2013 by Aboagye, E. O., Aigbirhio, F. I., Allen, P., Arent, R., Arrowsmith, R. L., Banci, G., Bagley, M. C., Bailey, C. D., Blake, T., Bunt, A. J., Bushby, N., Carroll, L., Cons, B. D., Cortezon, F., Dilworth, J. R., Dorff, P. N., Eggleston, I. M., Ellames, G., Elmore, C. S., Ernst, G., Estrela, P., Faithfull, J., Ge, H., Geach, N. J., Hall, J., Harding, J., Harwood, L. M., Hickey, M. J., Heys, J. R., Hogg, C., Hudson, M. J., James, T., Kerr, W. J., Killick, D., Kingston, L. P., Kociok-Köhn, G., Landvatter, S., Lewis, F., Lockley, W. J. S., Marken, F., Mudd, R. J., Pascu, S. I., Pheko, T., Powell, M. E., Reid, M, Riss, P. J., Ruhl, T., Rustidge, D. C., Schenk, D. J., Schofield, C., Schweiger, L., Sharma, P., Smith, D., Tuttle, C. T. T., Testa, A., Tyson, J. A., Tyrrell, R. M., Urbanek, R., Wilkinson, D. J., Willis, C. L., Zanda, M.

“…Meeting Summary The 22nd annual symposium of the International Isotope Society's United Kingdom Group took place at the Møller Centre, Churchill College,…”
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Witnessed embolization of a right atrial mass during transesophageal echocardiography: implications regarding the safety of esophageal intubation by Kwak, K D, Mosher, S F, Willis, C L, Kimura, B J

“…A patient with chronic lung disease and a right atrial density that was difficult to distinguish on a transthoracic echocardiogram underwent transesophageal…”
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Growth, incidence and activities of dissimilatory sulfate-reducing bacteria in the human oral cavity by Willis, C L, Gibson, G R, Allison, C, Macfarlane, S, Holt, J S

“…Viable counts and activities of sulfate-reducing bacteria were determined in the oral cavities of 12 healthy volunteers. Of these, 10 harboured viable…”
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The effect of dietary sodium and potassium intake on potassium secretion and kinetics in rat distal colon by Edmonds, C J, Willis, C L

“…1. Potassium secretion by the distal colon was examined in relation to the secretion of chloride and absorption of sodium and to the epithelial turnover of…”
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Irreversible Inhibition of High‐Affinity [3H]Kainate Binding by a Novel Photoactivatable Analogue: (2′S,3′S,4′R)‐2′‐Carboxy‐4′‐(2‐Diazo‐1‐Oxo‐3,3,3‐Trifluoropropyl)‐3′‐Pyrrolidinyl Acetate by Willis, Colin L., Wacker, Dean A., Bartlett, Richard D., Bleakman, David, Lodge, David, Chamberlin, A. Richard, Bridges, Richard J.

“…: A photolabile trifluoromethyldiazoketone derivative of kainate (KA), (2′S,3′S,4′R)‐2′‐carboxy‐4′‐(2‐diazo‐1‐oxo‐3,3,3‐trifluoropropyl)‐3′‐pyrrolidinyl…”
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Neuronal damage induced by beta-N-oxalylamino-L-alanine, in the rat hippocampus, can be prevented by a non-NMDA antagonist, 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline by Willis, C L, Meldrum, B S, Nunn, P B, Anderton, B H, Leigh, P N

“…The neurotoxin beta-N-oxalylamino-L-alanine (BOAA), found in Lathyrus sativus seeds, is thought to be the causative agent of neurolathyrism. We have…”
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Aldosterone and thyroid hormone interaction on the sodium and potassium transport pathways of rat colonic epithelium by Edmonds, C J, Willis, C L

“…The effect of hypothyroidism on potassium adaptation (shown by increased potassium secretion in response to potassium loading) and on the action of aldosterone…”
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Plasma and CSF levels of dizocilpine (MK-801) required for neuroprotection in the quinolinate-injected rat striatum by Willis, C L, Brazell, C, Foster, A C

“…This study has identified the range of plasma and cerebrospinal fluid (CSF) concentrations of the uncompetitive N-methyl-D-aspartate receptor antagonist…”
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Methylation of the NMDA receptor agonist L-trans-2,3-pyrrolidine-dicarboxylate : Enhanced excitotoxic potency and selectivity by WILLIS, C. L, DAUENHAUER, D. L, HUMPHREY, J. M, CHAMBERLIN, A. R, BULLER, A. L, MONAGHAN, D. T, BRIDGES, R. J

“…This study investigated the excitotoxic properties of a novel series of NMDA analogues in which a methyl group was introduced to the 5-position of the…”
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Potassium secretion by rat distal colon during acute potassium loading: effect of sodium, potassium intake and aldosterone by Edmonds, C J, Willis, C L

“…1. Potassium secretion by the distal colon before and during intravenous infusion of a potassium load was measured in vivo in groups of rats treated in various…”
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