Search Results - "Willis, Antony C"
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2-Carboxy-D-arabinitol 1-phosphate (CA1P) phosphatase: evidence for a wider role in plant Rubisco regulation
Published in Biochemical journal (15-03-2012)“…The genes for CA1Pase (2-carboxy-D-arabinitol-1-bisphosphate phosphatase) from French bean, wheat, Arabidopsis and tobacco were identified and cloned. The…”
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Localization of the Delta-like-1-binding Site in Human Notch-1 and Its Modulation by Calcium Affinity
Published in The Journal of biological chemistry (25-04-2008)“…The Notch signaling pathway plays a key role in a myriad of cellular processes, including cell fate determination. Despite extensive study of the downstream…”
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Control of Periplasmic Interdomain Thiol:Disulfide Exchange in the Transmembrane Oxidoreductase DsbD
Published in The Journal of biological chemistry (30-01-2009)“…The bacterial protein DsbD transfers reductant from the cytoplasm to the otherwise oxidizing environment of the periplasm. This reducing power is required for…”
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Structural Consequences of Cysteine Substitutions C1977Y and C1977R in Calcium-binding Epidermal Growth Factor-like Domain 30 of Human Fibrillin-1
Published in The Journal of biological chemistry (03-12-2004)“…The largest group of disease-causing mutations affecting calcium-binding epidermal growth factor-like (cbEGF) domain function in a wide variety of…”
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Identification and Characterization of a Novel Interaction between Pulmonary Surfactant Protein D and Decorin
Published in The Journal of biological chemistry (11-07-2003)“…Surfactant-associated protein D (SP-D) is a collectin that is present in lung surfactant and mucosal surfaces. Although SP-D regulates diverse functions, only…”
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The reaction mechanism of the internal thioester in the human complement component C4
Published in Nature (London) (11-01-1996)“…A key step in the elimination of pathogens from the body is the covalent binding of complement proteins C3 and C4 to their surfaces. Proteolytic activation of…”
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Cancer-associated Cleavage of Cytokeratin 8/18 Heterotypic Complexes Exposes a Neoepitope in Human Adenocarcinomas
Published in The Journal of biological chemistry (14-06-2002)“…The intermediate filament network in simple glandular epithelial cells predominantly consists of heterotypic complexes of cytokeratin 8 (K8) and cytokeratin 18…”
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The Covalent Binding Reaction of Complement Component C3
Published in The Journal of immunology (1950) (15-07-1998)“…The covalent binding of C3 to target molecules on the surfaces of pathogens is crucial in most complement-mediated activities. When C3 is activated, the acyl…”
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Maternal undernutrition during the preimplantation period of rat development causes blastocyst abnormalities and programming of postnatal hypertension
Published in Development (Cambridge) (01-10-2000)“…Epidemiological studies have indicated that susceptibility of human adults to hypertension and cardiovascular disease may result from intrauterine growth…”
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Characterization of complexes formed between TSG-6 and inter-alpha-inhibitor that act as intermediates in the covalent transfer of heavy chains onto hyaluronan
Published in The Journal of biological chemistry (08-07-2005)“…The high molecular mass glycosaminoglycan hyaluronan (HA) can become modified by the covalent attachment of heavy chains (HCs) derived from the serum protein…”
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Order within a mosaic distribution of mitochondrial c-type cytochrome biogenesis systems
Published in The FEBS journal (01-05-2008)“…Mitochondrial cytochromes c and c₁ are present in all eukaryotes that use oxygen as the terminal electron acceptor in the respiratory chain. Maturation of…”
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Lymphoid/Neuronal Cell Surface OX2 Glycoprotein Recognizes a Novel Receptor on Macrophages Implicated in the Control of Their Function
Published in Immunity (Cambridge, Mass.) (01-08-2000)“…The OX2 membrane glycoprotein (CD200) is expressed on a broad range of tissues including lymphoid cells, neurons, and endothelium. We report the…”
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Cellular and molecular studies of Marfan syndrome mutations identify co-operative protein folding in the cbEGF12–13 region of fibrillin-1
Published in Human molecular genetics (15-04-2007)“…Human fibrillin-1 is an extra-cellular matrix glycoprotein with a modular organisation that includes 43 calcium-binding epidermal growth factor-like (cbEGF)…”
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Domain organization of the extracellular region of CD45
Published in Protein engineering (01-10-1999)“…CD45 is a large, heavily glycosylated, transmembrane protein phosphotyrosine phosphatase found on all nucleated cells of haematopoietic origin. In lymphocytes,…”
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Isolation and Characterization of a New Member of the Scavenger Receptor Superfamily, Glycoprotein-340 (gp-340), as a Lung Surfactant Protein-D Binding Molecule
Published in The Journal of biological chemistry (23-05-1997)“…We have purified a previously unknown glycoprotein (designated gp-340) from human bronchioalveolar lung washings from a patient with alveolar proteinosis…”
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The Catalytically Active Serine Protease Domain of Human Complement Factor I
Published in Biochemistry (Easton) (26-04-2005)“…Factor I (fI) is a major regulator of complement. As a protease it has very restricted specificity, cleaving only C3b or C4b in the presence of a cofactor such…”
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PCP-A1, a defensin-like brassica pollen coat protein that binds the S locus glycoprotein, is the product of gametophytic gene expression
Published in The Plant cell (01-08-1998)“…Self-incompatibility (SI) in Brassica species is controlled by a single polymorphic locus (S) with multiple specificities. Two stigmatically expressed genes…”
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Ficolin-MASPs in complement and coagulation pathways
Published in Molecular immunology (01-09-2007)Get full text
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Gamma III-crystallin is the primary target of glycation in the bovine lens incubated under physiological conditions
Published in Biochemical journal (15-09-2003)“…Several mechanisms have been proposed for the way in which glucose and its metabolites cause cataract, retinopathy and other complications of diabetes, the…”
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A new macrophage differentiation antigen which is a member of the scavenger receptor superfamily
Published in European journal of immunology (01-09-1993)“…The antibodies Ki-M8, Ber-Mac3, GHI/61 and SM4 define a human macrophage-associated antigen with a relative molecular mass of 130,000 which we designate M130…”
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