Search Results - "Willing, Alison"

Treatment with shCCL20-CCR6 nanodendriplexes and human mesenchymal stem cell therapy improves pathology in mice with repeated traumatic brain injury by Mayilsamy, Karthick, Markoutsa, Eleni, Das, Mahasweta, Chopade, Pratik, Puro, Durga, Kumar, Akanksha, Gulick, Danielle, Willing, Alison E., Mohapatra, Shyam S, Mohapatra, Subhra

“…Traumatic brain injury (TBI) is a devastating neurological disorder, although the underlying pathophysiology is poorly understood. TBI causes blood–brain…”
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Potential of mesenchymal stem cells alone, or in combination, to treat traumatic brain injury by Willing, Alison E., Das, Mahasweta, Howell, Mark, Mohapatra, Shyam S., Mohapatra, Subhra

“…Traumatic brain injury (TBI) causes death and disability in the United States and around the world. The traumatic insult causes the mechanical injury of the…”
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Pioglitazone treatment prior to transplantation improves the efficacy of human mesenchymal stem cells after traumatic brain injury in rats by Das, Mahasweta, Mayilsamy, Karthick, Tang, Xiaolan, Han, Jung Yeon, Foran, Elspeth, Willing, Alison E., Mohapatra, Shyam S., Mohapatra, Subhra

“…Traumatic brain injury is a leading cause of death and disability around the world. So far, drugs are not available to repair brain damage. Human mesenchymal…”
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Cell-Free Extracellular Vesicles Derived from Human Bone Marrow Endothelial Progenitor Cells as Potential Therapeutics for Microvascular Endothelium Restoration in ALS by Garbuzova-Davis, Svitlana, Willing, Alison E., Ehrhart, Jared, Wang, Lianchun, Sanberg, Paul R., Borlongan, Cesario V.

“…Repairing the damaged blood-CNS-barrier in amyotrophic lateral sclerosis (ALS) is necessary to prevent entry of detrimental blood-borne factors contributing to…”
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Human umbilical cord blood treatment in a mouse model of ALS: optimization of cell dose by Garbuzova-Davis, Svitlana, Sanberg, Cyndy Davis, Kuzmin-Nichols, Nicole, Willing, Alison E, Gemma, Carmelina, Bickford, Paula C, Miller, Christina, Rossi, Robert, Sanberg, Paul R

“…Amyotrophic Lateral Sclerosis (ALS) is a multicausal disease characterized by motor neuron degeneration in the spinal cord and brain. Cell therapy may be a…”
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A Transient Decrease in Spleen Size Following Stroke Corresponds to Splenocyte Release into Systemic Circulation by Seifert, Hilary A., Hall, Aaron A., Chapman, Cortney B., Collier, Lisa A., Willing, Alison E., Pennypacker, Keith R.

“…The splenic response to stroke is a proinflammatory reaction to ischemic injury resulting in expanded neurodegeneration. Splenectomy reduces neural injury in…”
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Discrete mitochondrial aberrations in the spinal cord of sporadic ALS patients by Delic, Vedad, Kurien, Crupa, Cruz, Josean, Zivkovic, Sandra, Barretta, Jennifer, Thomson, Avery, Hennessey, Daniel, Joseph, Jaheem, Ehrhart, Jared, Willing, Alison E., Bradshaw, Patrick, Garbuzova‐Davis, Svitlana

“…Amyotrophic lateral sclerosis (ALS) is an adult onset neurodegenerative disease characterized by progressive motor neuron degeneration in the brain and spinal…”
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Pro-Inflammatory Interferon Gamma Signaling is Directly Associated with Stroke Induced Neurodegeneration by Seifert, Hilary A., Collier, Lisa A., Chapman, Cortney B., Benkovic, Stanley A., Willing, Alison E., Pennypacker, Keith R.

“…The delayed immune response to stroke is responsible for the increased neural injury that continues to occur after the initial ischemic event. This delayed…”
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Amyotrophic lateral sclerosis: A neurovascular disease by Garbuzova-Davis, Svitlana, Rodrigues, Maria C.O, Hernandez-Ontiveros, Diana G, Louis, Michael K, Willing, Alison E, Borlongan, Cesario V, Sanberg, Paul R

“…Abstract Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative disease with a complicated pathogenesis. Compelling evidence indicates impairment of…”
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The spleen contributes to stroke-induced neurodegeneration by Ajmo Jr, Craig T., Vernon, Dionne O. L., Collier, Lisa, Hall, Aaron A., Garbuzova-Davis, Svitlana, Willing, Alison, Pennypacker, Keith R.

“…Stroke, a cerebrovascular injury, is the leading cause of disability and third leading cause of death in the world. Recent reports indicate that inhibiting the…”
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Infusion of human umbilical cord blood cells in a rat model of stroke dose-dependently rescues behavioral deficits and reduces infarct volume by VENDRAME, Martina, CASSADY, Jordan, NEWCOMB, Jennifer, BUTLER, Tanya, PENNYPACKER, Keith R, ZIGOVA, Tanja, SANBERG, Cyndy Davis, SANBERG, Paul R, WILLING, Alison E

“…Intravenously delivered human umbilical cord blood cells (HUCBC) have been previously shown to improve functional recovery of stroked rats. To extend these…”
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Advancing Stem Cell Therapy for Repair of Damaged Lung Microvasculature in Amyotrophic Lateral Sclerosis by Garbuzova-Davis, Svitlana, Shell, Robert, Mustafa, Hilmi, Hailu, Surafuale, Willing, Alison E., Sanberg, Paul R., Borlongan, Cesario V.

“…Amyotrophic lateral sclerosis (ALS) is a fatal disease of motor neuron degeneration in the brain and spinal cord. Progressive paralysis of the diaphragm and…”
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Apolipoprotein A1 Enhances Endothelial Cell Survival in an In Vitro Model of ALS by Garbuzova-Davis, Svitlana, Willing, Alison E, Borlongan, Cesario V

“…Altered lipoprotein metabolism is considered a pathogenic component of amyotrophic lateral sclerosis (ALS). Apolipoprotein A1 (ApoA1), a major high-density…”
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Peripheral injection of human umbilical cord blood stimulates neurogenesis in the aged rat brain by Bachstetter, Adam D, Pabon, Mibel M, Cole, Michael J, Hudson, Charles E, Sanberg, Paul R, Willing, Alison E, Bickford, Paula C, Gemma, Carmelina

“…Neurogenesis continues to occur throughout life but dramatically decreases with increasing age. This decrease is mostly related to a decline in proliferative…”
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Cord blood rescues stroke-induced changes in splenocyte phenotype and function by Vendrame, Martina, Gemma, Carmelina, Pennypacker, Keith R., Bickford, Paula C., Davis Sanberg, Cyndy, Sanberg, Paul R., Willing, Alison E.

“…The neuroprotective mechanism of human umbilical cord blood cells (HUCBC) in the rat middle cerebral artery occlusion (MCAO) stroke model remains uncertain…”
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The spleen contributes to stroke induced neurodegeneration through interferon gamma signaling by Seifert, Hilary A., Leonardo, Christopher C., Hall, Aaron A., Rowe, Derrick D., Collier, Lisa A., Benkovic, Stanley A., Willing, Alison E., Pennypacker, Keith R.

“…Delayed neuronal death associated with stroke has been increasingly linked to the immune response to the injury. Splenectomy prior to middle cerebral artery…”
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Experimental Models: Help or Hindrance by WILLING, Alison E

“…Although many potential therapeutics have improved motor and cognitive function in animal models of experimental stroke, very few have been found to have…”
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Blockade of adrenoreceptors inhibits the splenic response to stroke by Ajmo, Craig T., Collier, Lisa A., Leonardo, Christopher C., Hall, Aaron A., Green, Suzanne M., Womble, Tracy A., Cuevas, Javier, Willing, Alison E., Pennypacker, Keith R.

“…Recent studies have highlighted the involvement of the peripheral immune system in delayed cellular degeneration after stroke. In the permanent middle cerebral…”
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Leukemia inhibitor factor promotes functional recovery and oligodendrocyte survival in rat models of focal ischemia by Rowe, Derrick D., Collier, Lisa A., Seifert, Hilary A., Chapman, Cortney B., Leonardo, Christopher C., Willing, Alison E., Pennypacker, Keith R.

“…Human umbilical cord blood (HUCB) cells have shown efficacy in rodent models of focal ischemia and in vitro systems that recapitulate stroke conditions. One…”
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Brazilian Jiu Jitsu Training for US Service Members and Veterans with Symptoms of PTSD by Willing, Alison E, Girling, Sue Ann, Deichert, Ryan, Wood-Deichert, Rebecca, Gonzalez, Jason, Hernandez, Diego, Foran, Elspeth, Sanberg, Paul R, Kip, Kevin E

“…Abstract Introduction The United States has been actively involved in major armed conflicts over the last 15 years. As a result, a significant proportion of…”
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